Valtoco Dosage

Medically reviewed by Drugs.com. Last updated on Feb 16, 2021.

Generic name: diazepam 5mg in 0.1mL
Dosage form: nasal spray

Instructions Prior to Dosing

Prior to treatment, healthcare professionals should instruct the individual administering VALTOCO on how to identify seizure clusters and use the product appropriately [see Dosage and Administration (2.3) and Patient Counseling Information (17)].

Dosing Information

The recommended dose of VALTOCO nasal spray is 0.2 mg/kg or 0.3 mg/kg, depending on the patient's age and weight. See Table 1 for specific recommendations.

The following table provides the acceptable weight ranges for each dose and age category, such that patients will receive between 90% and 180% of the calculated recommended dose.

Table 1: Recommended Dosage for Adults and Pediatric Patients 6 Years of Age and Older
Dose Based on Age and Weight			Administration
6 to 11 Years of Age (0.3 mg/kg)	12 Years of Age and Older (0.2 mg/kg)	Dose (mg)	Number of Nasal Spray Devices	Number of Sprays
Weight (kg)	Weight (kg)
10 to 18	14 to 27	5	One 5 mg device	One spray in one nostril
19 to 37	28 to 50	10	One 10 mg device	One spray in one nostril
38 to 55	51 to 75	15	Two 7.5 mg devices	One spray in each nostril
56 to 74	76 and up	20	Two 10 mg devices	One spray in each nostril

Second Dose (if needed): A second dose, when required, may be administered after at least 4 hours after the initial dose. If the second dose is to be administered, use a new blister pack of VALTOCO.

Maximum Dosage and Treatment Frequency: Do not use more than 2 doses of VALTOCO to treat a single episode.

It is recommended that VALTOCO be used to treat no more than one episode every five days and no more than five episodes per month.

Important Administration Instructions

VALTOCO is for intranasal use only.

No device assembly is required. VALTOCO is a ready-to-use nasal spray device. VALTOCO nasal spray delivers its entire contents upon activation. Do not prime or attempt to use for more than one administration per device.

Patients and caregivers should be counseled to read carefully the "Instructions for Use" for complete directions on how to properly administer VALTOCO.