Valtoco Dosage

Generic name: diazepam 5mg in 0.1mL
Dosage form: nasal spray
Drug class: Benzodiazepine anticonvulsants

Medically reviewed by Drugs.com. Last updated on May 6, 2025.

Instructions Prior to Dosing

Prior to treatment, healthcare professionals should instruct the individual administering VALTOCO on how to identify seizure clusters and use the product appropriately.

Dosing Information

The recommended dose of VALTOCO nasal spray is 0.2 mg/kg to 0.5 mg/kg, depending on the patient's age and weight. See Table 1 and Table 2 for specific recommendations.

Table 1: Recommended Dose Based on Age
Age (Years)	Recommended Dose
2 through 5	0.5 mg/kg
6 through 11	0.3 mg/kg
12 and older	0.2 mg/kg

Table 2: Recommended Dosage and Administration for Adults and Pediatric Patients 2 Years of Age and Older
Dose Based on Age and Weight				Administration
2 to 5 Years of Age (0.5 mg/kg)	6 to 11 Years of Age (0.3 mg/kg)	12 Years of Age and Older (0.2 mg/kg)	Dose (mg)	Number of Nasal Spray Devices	Number of Sprays
Weight (kg)
6 to 11	10 to 18	14 to 27	5	One 5 mg device	One spray in one nostril
12 to 22	19 to 37	28 to 50	10	One 10 mg device	One spray in one nostril
23 to 33	38 to 55	51 to 75	15	Two 7.5 mg devices	One spray in each nostril
	56 to 74	76 and up	20	Two 10 mg devices	One spray in each nostril

Second Dose (if needed): A second dose, when required, may be administered after at least 4 hours after the initial dose. If the second dose is to be administered, use a new blister pack of VALTOCO.

Maximum Dosage and Treatment Frequency: Do not use more than 2 doses of VALTOCO to treat a single episode.

Do not use VALTOCO to treat more than one episode every five days or more than five episodes per month.

Important Administration Instructions

VALTOCO is for intranasal use only.

No device assembly is required. VALTOCO nasal spray delivers its entire contents upon activation. Do not prime or attempt to use for more than one administration per device.

Patients and caregivers should be counseled to read carefully the "Instructions for Use" for complete directions on how to properly administer VALTOCO.