Generic name: diazepam 5mg in 100uL
Dosage form: nasal spray
Medically reviewed by Drugs.com. Last updated on Jan 13, 2020.
Instructions Prior to Dosing
Prior to treatment, healthcare professionals should instruct the individual administering VALTOCO on how to identify seizure clusters and use the product appropriately [see Dosage and Administration (2.3) and Patient Counseling Information (17)].
The recommended dose of VALTOCO nasal spray is 0.2 mg/kg or 0.3 mg/kg, depending on the patient's age and weight. See Table 1 for specific recommendations.
The following table provides the acceptable weight ranges for each dose and age category, such that patients will receive between 90% and 180% of the calculated recommended dose.
|Dose Based on Age and Weight||Administration|
|6 to 11 Years of Age
|12 Years of Age and Older
|Dose (mg)||Number of Nasal Spray Devices||Number of Sprays|
|Weight (kg)||Weight (kg)|
|10 to 18||14 to 27||5||One 5 mg device||One spray in one nostril|
|19 to 37||28 to 50||10||One 10 mg device||One spray in one nostril|
|38 to 55||51 to 75||15||Two 7.5 mg devices||One spray in each nostril|
|56 to 74||76 and up||20||Two 10 mg devices||One spray in each nostril|
Second Dose (if needed): A second dose, when required, may be administered after at least 4 hours after the initial dose. If the second dose is to be administered, use a new blister pack of VALTOCO.
Important Administration Instructions
VALTOCO is for intranasal use only.
No device assembly is required. VALTOCO is a ready-to-use nasal spray device. VALTOCO nasal spray delivers its entire contents upon activation. Do not prime or attempt to use for more than one administration per device.
Patients and caregivers should be counseled to read carefully the "Instructions for Use" for complete directions on how to properly administer VALTOCO.
More about Valtoco (diazepam)
- Side Effects
- During Pregnancy or Breastfeeding
- Drug Interactions
- En Español
- Drug class: benzodiazepine anticonvulsants
- FDA Alerts (1)
- FDA Approval History