Medically reviewed by Drugs.com. Last updated on Feb 11, 2021.
Generic name: midazolam 5mg in 0.1mL
Dosage form: nasal spray
Instructions Prior to Dosing
NAYZILAM prescribers should consider the following prior to initiation of treatment:
For patients at increased risk of respiratory depression from benzodiazepines, administration of NAYZILAM under healthcare professional supervision should be considered prior to treatment with NAYZILAM; this administration may be performed in the absence of a seizure episode [see Warnings and Precautions (5.4)].
Prior to treatment, the healthcare professional should instruct the individual administering NAYZILAM on how to identify seizure clusters and use the product appropriately [see Patient Counseling Information: Administration Information (17)]. Patients and caregivers should be counseled to read carefully the "Instructions for Use" for complete directions on how to properly administer NAYZILAM.
Administer NAYZILAM by the nasal route only.
Second Dose (if needed): One additional spray (5 mg dose) into the opposite nostril may be administered after 10 minutes if the patient has not responded to the initial dose.
A second dose of NAYZILAM should not be administered if the patient has trouble breathing or if there is excessive sedation that is uncharacteristic of the patient during a seizure cluster episode [see Warnings and Precautions (5.4)].
Maximum Dosage and Treatment Frequency: Do not use more than 2 doses of NAYZILAM to treat a single episode.
It is recommended that NAYZILAM be used to treat no more than one episode every three days and no more than 5 episodes per month [see Drug Abuse and Dependence (9.4)].
More about Nayzilam (midazolam)
- Side Effects
- During Pregnancy or Breastfeeding
- Drug Interactions
- Pricing & Coupons
- En Español
- Drug class: benzodiazepines
- FDA Alerts (4)
- FDA Approval History
- Other brands
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Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.