What is midazolam?
Midazolam is a benzodiazepine (ben-zoe-dye-AZE-eh-peen) that is used to help you relax before having a minor surgery, dental work, or other medical procedure.
Midazolam may also be used for purposes not listed in this medication guide.
Midazolam can slow or stop your breathing, especially if you have recently used an opioid medication or alcohol. Midazolam is given in a hospital, dentist office, or other clinic setting where your vital signs can be watched closely.
Before taking this medicine
You should not use midazolam if you are allergic to it, or if you have:
untreated or uncontrolled open-angle glaucoma; or
an allergy to cherries.
Tell your doctor if you have ever had:
breathing problems; or
congestive heart failure.
Tell your doctor if you are pregnant or breastfeeding.
How should I take midazolam?
Midazolam is usually given as a single dose just before your surgery or procedure.
Midazolam can slow or stop your breathing, especially if you have recently used an opioid medication or alcohol. Midazolam should be used only in a hospital, dentist office, or other clinic setting where any serious side effects can be quickly treated.
After you take midazolam, you will be watched closely to make sure the medicine is working and does not cause harmful side effects.
Your breathing, blood pressure, oxygen levels, and other vital signs will be watched closely while you are in surgery.
What happens if I miss a dose?
In a medical setting you are not likely to miss a dose.
What happens if I overdose?
In a medical setting an overdose would be treated quickly.
What should I avoid after taking midazolam?
Do not drink alcohol shortly after taking midazolam. midazolam can increase the effects of alcohol, which could be dangerous.
Grapefruit may interact with midazolam and cause side effects. Avoid consuming grapefruit products for a short time after taking midazolam.
You may feel drowsy for 24 to 48 hours after the injection. Avoid driving or hazardous activity until the effects of midazolam have worn off completely. Dizziness or drowsiness can cause falls, accidents, or severe injuries.
Midazolam side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Midazolam can slow or stop your breathing, especially if you have recently used an opioid medication, alcohol, or other drugs that can slow your breathing. Your caregivers will watch you for symptoms such as weak or shallow breathing.
Tell your medical caregivers right away if you have:
cough, wheezing, trouble breathing;
a light-headed feeling, like you might pass out;
confusion, agitation, hallucinations, unusual thoughts or behavior.
Drowsiness or dizziness may last longer in older adults. Use caution to avoid falling or accidental injury.
Common side effects of midazolam may include:
amnesia or forgetfulness after your procedure;
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect midazolam?
Shortly after you are treated with midazolam, using other drugs that make you sleepy or slow your breathing can cause dangerous side effects or death. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.
More about midazolam
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- Midazolam nasal
- Midazolam (Advanced Reading)
- Midazolam Injection (Advanced Reading)
- Midazolam Nasal (Advanced Reading)
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Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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