Generic name: midazolam (injection) (mi DAZ oh lam)
Dosage forms: injectable solution (0.5 mg/mL preservative-free-D5%; 1 mg/mL; 1 mg/mL preservative-free; 1 mg/mL preservative-free-D5%; 1 mg/mL-NaCl 0.8%; 1 mg/mL-NaCl 0.9%; 2 mg/mL-NaCl 0.9%; 200 mg/200 mL-D5%; 5 mg/mL; 5 mg/mL preservative-free); intravenous solution (0.5 mg/mL-NaCl 0.9%; 1 mg/mL preservative-free; 1 mg/mL-NaCl 0.9%; 2 mg/mL-NaCl 0.9%; 200 mg/200 mL-D5%)
Drug class: Benzodiazepines
What is midazolam?
Midazolam is a benzodiazepine (ben-zoe-dye-AZE-eh-peen) that is used to help you relax before having a minor surgery, dental work, or other medical procedure. Midazolam injection is also used to sedate a patient who needs a ventilator.
Midazolam injection may also be used for purposes not listed in this medication guide.
Midazolam can slow or stop your breathing, especially if you have recently used an opioid medication, alcohol, or other drugs that can slow your breathing.
Before taking this medicine
You should not be treated with midazolam if you are allergic to it, or if you have:
Tell your doctor if you've ever had:
kidney failure; or
congestive heart failure.
Tell your doctor if you are pregnant or breastfeeding.
Midazolam may harm an unborn baby, and generally should not be used during pregnancy.
Sedatives used during surgery may affect brain development in a young child or unborn baby (when used in the mother), which may lead to learning or behavior problems later in life. Long surgeries or repeated procedures pose the highest risks.
It may still be necessary to use a sedative for a life-threatening condition, medical emergency, or surgery to correct a birth defect. Your doctor can inform you about all medicines given during a surgery or procedure.
How is midazolam injection given?
Midazolam is injected into a muscle or vein by a healthcare provider.
Your breathing, blood pressure, oxygen levels, and other vital signs will be watched closely.
Midazolam injection is for a single use, or for continuous infusion in a person on a ventilator. Ongoing use of midazolam may be habit-forming or cause withdrawal symptoms when you stop using the medicine.
What happens if I miss a dose?
In a medical setting you are not likely to miss a dose.
What happens if I overdose?
In a medical setting an overdose would be treated quickly.
What should I avoid after receiving midazolam?
Avoid drinking alcohol within the first 1 or 2 days after you receive midazolam injection.
Avoid driving or hazardous activity until the effects of midazolam have worn off completely, or until 24 hours after injection (whichever comes first). Dizziness or drowsiness can cause falls, accidents, or severe injuries.
Midazolam side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Midazolam can slow or stop your breathing, especially if you have recently used an opioid medication, alcohol, or other drugs that can slow your breathing. Your medical caregivers will watch you for symptoms such as weak or shallow breathing.
Tell your medical caregivers right away if you have:
confusion, agitation; or
tremors, uncontrolled muscle movements.
Drowsiness or dizziness may last longer in older adults. Use caution to avoid falling or accidental injury. You may need help getting out of bed for at least the first 8 hours.
Common side effects may include:
pain, redness, or a hard lump where the medicine was injected.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect midazolam?
Shortly after you are treated with midazolam, using other drugs that make you sleep or slow your breathing can cause dangerous side effects or death. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.
Tell your doctor about all your other medicines, especially:
antibiotic or antifungal medicine;
heart or blood pressure medicine; or
HIV or AIDS medication.
More about midazolam
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- Compare Alternatives
- Pricing & Coupons
- 114 Reviews
- Drug class: benzodiazepines
- Drug Information
- Midazolam nasal
- Midazolam (Advanced Reading)
- Midazolam Injection (Advanced Reading)
- Midazolam Nasal (Advanced Reading)
Related treatment guides
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Copyright 1996-2021 Cerner Multum, Inc. Version: 4.01.