Midazolam Alternatives Compared
| Midazolam | Diazepam | Valium |
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| Midazolam | Diazepam | Valium diazepam |
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Prescribed for Light Sedation, ICU Agitation, Light Anesthesia, Seizures, Status Epilepticus. midazolam may also be used for purposes not listed in this medication guide. |
Diazepam may be used occasionally to relieve anxiety and prolonged seizures; however, it is addictive and withdrawal symptoms can be severe. Prescribed for Anxiety, Endoscopy or Radiology... View more |
Valium may be used occasionally to relieve anxiety and some other conditions such as acute muscle spasms and alcohol withdrawal. However, it is addictive and withdrawal symptoms can be severe... View more |
Choose a suggestion below Seizures (Convulsions)
Light Sedation
Light Anesthesia
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| More about Midazolam | More about Diazepam | More about Valium (diazepam) | ||||||||||||||||||||||||
| Generic Status | ||||||||||||||||||||||||||
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Prescription only |
Prescription only |
Prescription only |
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| Ratings & Reviews | ||||||||||||||||||||||||||
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Midazolam has an average rating of 4.2 out of 10 from a total of 123 ratings on Drugs.com. 34% of reviewers reported a positive effect, while 60% reported a negative effect. |
Diazepam has an average rating of 8.4 out of 10 from a total of 765 ratings on Drugs.com. 82% of reviewers reported a positive effect, while 10% reported a negative effect. |
Valium has an average rating of 8.7 out of 10 from a total of 300 ratings on Drugs.com. 86% of reviewers reported a positive effect, while 7% reported a negative effect. |
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| Drug Class | ||||||||||||||||||||||||||
| Side Effects | ||||||||||||||||||||||||||
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Commonly reported side effects include: apnea, bradypnea. See the full midazolam side effects document. |
Commonly reported side effects include: drowsiness, hypotonia. See the full diazepam side effects document. |
Common side effects include: hypotonia. See the full Valium side effects document. |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all midazolam prices |
View all diazepam prices |
View all Valium prices and generic prices |
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| Dosage Form(s) Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Nayzilam, Seizalam | Diastat, Diastat AcuDial, Diastat Pediatric, Diazepam Intensol, Valium, Valtoco | Other diazepam brands include: Diastat, Diastat AcuDial, Diastat Pediatric, Diazepam Intensol, Valtoco | ||||||||||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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4 hours |
70 hours |
70 hours |
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| CSA Schedule** View glossary of terms | ||||||||||||||||||||||||||
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Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category D
Positive evidence of risk
See the full Pregnancy Warnings document. |
Category D
Positive evidence of risk
See the full Pregnancy Warnings document. |
Category D
Positive evidence of risk
See the full Pregnancy Warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 500 drugs are known to interact with midazolam:
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A total of 488 drugs are known to interact with diazepam:
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A total of 488 drugs are known to interact with Valium:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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October 15, 1998 |
November 15, 1963 |
November 15, 1963 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
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| Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.