Comparing Diazepam vs Midazolam
| Diazepam | Midazolam |
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| Diazepam | Midazolam |
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Prescription only
Diazepam may be used occasionally to relieve anxiety and prolonged seizures; however, it is addictive and withdrawal symptoms can be severe. Prescribed for Anxiety, Back Pain, Alcohol Withdrawal... View more |
Prescription only
Prescribed for Light Sedation, ICU Agitation, Light Anesthesia, Seizures, Status Epilepticus. midazolam may also be used for purposes not listed in this medication guide. |
Related suggestions Light Sedation
Light Anesthesia
ICU Agitation
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| More about Diazepam | More about Midazolam | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Diazepam has an average rating of 8.5 out of 10 from a total of 861 ratings on Drugs.com. 82% of reviewers reported a positive effect, while 9% reported a negative effect. |
Midazolam has an average rating of 4.4 out of 10 from a total of 144 ratings on Drugs.com. 36% of reviewers reported a positive effect, while 59% reported a negative effect. |
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| Drug Class | |||||||||||||||||
| Side Effects | |||||||||||||||||
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See also: diazepam side effects in more detail. |
See also: midazolam side effects in more detail. |
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| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all diazepam prices |
View all midazolam prices |
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| Dosage Forms Available | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Diastat, Diastat AcuDial, Diastat Pediatric, Diazepam Intensol, Libervant, Valium, Valtoco | Nayzilam, Seizalam | ||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
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70 hours |
4 hours |
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| CSA Schedule ** View glossary of terms | |||||||||||||||||
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Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
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| Pregnancy Category | |||||||||||||||||
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Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 524 drugs are known to interact with diazepam:
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A total of 568 drugs are known to interact with midazolam:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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November 15, 1963 |
October 15, 1998 |
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| WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.