Comparing Clonazepam vs Diazepam

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Clonazepam	Diazepam	Enter another drug to compare

Clonazepam

Diazepam

Prescription only

Clonazepam may reduce seizure frequency in specific seizure disorders and can be used short-term for panic disorder, to relieve anxiety, or to sedate. When used long-term it can cause dependence and... View more

Prescription only

Diazepam may be used occasionally to relieve anxiety and prolonged seizures; however, it is addictive and withdrawal symptoms can be severe. Prescribed for Anxiety, Back Pain, Hyperekplexia... View more

More about Clonazepam

More about Diazepam

Ratings & Reviews

Clonazepam has an average rating of 8.2 out of 10 from a total of 2186 ratings on Drugs.com. 78% of reviewers reported a positive effect, while 12% reported a negative effect.

Diazepam has an average rating of 8.4 out of 10 from a total of 893 ratings on Drugs.com. 81% of reviewers reported a positive effect, while 9% reported a negative effect.

View all 2186 reviews

View all 893 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

Anxiety (7.1%)
Drowsiness (6.7%)
Withdrawal (6.5%)
Insomnia (4.7%)
Tiredness (3.2%)
Depression (3.2%)
Panic attacks (3.1%)

View all Clonazepam side effects

Anxiety (8.0%)
Drowsiness (5.5%)
Withdrawal (4.4%)
Addiction (3.0%)
Muscle spasms (3.0%)
Panic attacks (2.8%)
Tremors (2.6%)

View all Diazepam side effects

Drug Class

Generic Availability

Lower cost generic

Pricing and Coupons * Prices are without insurance

Quantity	10 tablet
Strength	0.5 mg
Per unit^*	$1.04 - $1.22
Cost^*	$10.36 - $12.19

View all Clonazepam prices

Quantity	4 tablet
Strength	5 mg
Per unit^*	$2.56
Cost^*	$10.22

View all Diazepam prices

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Dosage Forms

Oral tablet
Oral tablet, disintegrating

Injectable solution
Oral concentrate
Oral solution
Oral tablet
Rectal kit

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

40 hours

70 hours

CSA Schedule ¹ View glossary of CSA terms

Some potential for abuse

Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.

Some potential for abuse

Pregnancy Category

Category D Positive evidence of risk

See the full pregnancy warnings document.

Category D Positive evidence of risk

See the full pregnancy warnings document.

Drug Interactions

A total of 533 drugs are known to interact with Clonazepam:

30 major drug interactions (155 brand and generic names)
470 moderate drug interactions (1742 brand and generic names)
33 minor drug interactions (210 brand and generic names)

A total of 526 drugs are known to interact with Diazepam:

32 major drug interactions (166 brand and generic names)
448 moderate drug interactions (1666 brand and generic names)
46 minor drug interactions (386 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Using clonazePAM together with alcohol can increase nervous system side effects such as dizziness... View more

Grapefruit and grapefruit juice may interact with diazePAM and lead to potentially dangerous side... View more

Disease Interactions

First Approval Date

June 04, 1975

November 15, 1963

WADA Class View classifications

N/A

More Information

Patient Resources

Clonazepam uses

Diazepam uses

Professional Resources

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Clonazepam vs Diazepam

See also:

Xanax

Prozac

Botox

Ativan

Paroxetine

Lorazepam

Zoloft

Venlafaxine

Buspirone

Alprazolam

Further information

Comparing Clonazepam vs Diazepam

See also:

Further information

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