Vitamin B6 Side Effects
Generic name: pyridoxine
Medically reviewed by Drugs.com. Last updated on Apr 25, 2025.
Note: This document provides detailed information about Vitamin B6 Side Effects associated with pyridoxine. Some dosage forms listed on this page may not apply specifically to the brand name Vitamin B6.
Applies to pyridoxine: capsule, powder, solution, tablet, tablet extended release.
Serious side effects of Vitamin B6
Along with its needed effects, pyridoxine (the active ingredient contained in Vitamin B6) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor as soon as possible if any of the following side effects occur while taking pyridoxine:
With large doses
- Clumsiness
- numbness of hands or feet
For healthcare professionals
Applies to pyridoxine: compounding powder, injectable solution, oral capsule, oral tablet.
Nervous system adverse events
- Frequency not reported: Paresthesia, somnolence[Ref]
The profound sensory loss following treatment with high doses of parenteral pyridoxine may not be reversible.[Ref]
Metabolic
- Frequency not reported: Low serum folic acid levels[Ref]
See also:
Levetiracetam
Levetiracetam systemic is used for bipolar disorder, epilepsy, hyperekplexia, neuralgia, new daily ...
Diazepam
Diazepam is used to treat anxiety disorders, alcohol withdrawal symptoms, or muscle spasms. Learn ...
Reblozyl
Reblozyl is used to treat anemia in adults with beta-thalassemia or myelodysplastic syndromes ...
Dexamethasone
Dexamethasone is used to treat inflammatory conditions such as allergies, skin conditions ...
Zofran
Zofran (ondansetron) is used to prevent nausea and vomiting caused by surgery or cancer medicines ...
Olanzapine
Olanzapine (brand name Zyprexa) is an atypical antipsychotic that may be used to treat adults and ...
Pregabalin
Pregabalin may be used to treat certain types of pain and used in combination with other ...
Lorazepam
Lorazepam is in a group of drugs called benzodiazepines and is used to treat anxiety disorders ...
Clonazepam
Clonazepam is used to treat seizures and panic disorder. Learn about side effects, interactions and ...
Lamotrigine
Lamotrigine systemic is used for anxiety, bipolar disorder, borderline personality disorder ...
References
1. (2018) "Product Information. Pyridoxine Hydrochloride (pyridoxine)." APP (Abraxis Pharmaceutical Products)
More about Vitamin B6 (pyridoxine)
- Check interactions
- Compare alternatives
- Reviews (3)
- Dosage information
- During pregnancy
- Drug class: vitamins
- En español
Patient resources
Other brands
Professional resources
Related treatment guides
Further information
Vitamin B6 side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.