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Anxiety Medications

The medications listed below are related to or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
Xanax 8.4 561 reviews for Xanax to treat Anxiety Rx D 4 X
Generic name:
alprazolam systemic
Drug class:
benzodiazepines
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
clonazepam Off-label 8.4 825 reviews for clonazepam to treat Anxiety Rx D 4 X
Generic name:
clonazepam systemic
Drug class:
benzodiazepines, benzodiazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
alprazolam 8.5 867 reviews for alprazolam to treat Anxiety Rx D 4 X
Generic name:
alprazolam systemic
Brand names:
Xanax, Alprazolam Intensol
Drug class:
benzodiazepines
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
buspirone 6.0 1130 reviews for buspirone to treat Anxiety Rx B N X
Generic name:
buspirone systemic
Brand name:
BuSpar
Drug class:
miscellaneous anxiolytics, sedatives and hypnotics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
hydroxyzine 5.6 937 reviews for hydroxyzine to treat Anxiety Rx N N X
Generic name:
hydroxyzine systemic
Brand name:
Vistaril
Drug class:
miscellaneous anxiolytics, sedatives and hypnotics, antihistamines
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
lorazepam 8.0 686 reviews for lorazepam to treat Anxiety Rx D 4 X
Generic name:
lorazepam systemic
Brand names:
Ativan, Lorazepam Intensol, Loreev XR
Drug class:
benzodiazepines, miscellaneous antiemetics, benzodiazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Ativan 8.0 342 reviews for Ativan to treat Anxiety Rx D 4 X
Generic name:
lorazepam systemic
Drug class:
benzodiazepines, miscellaneous antiemetics, benzodiazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Lexapro 7.5 974 reviews for Lexapro to treat Anxiety Rx C N X
Generic name:
escitalopram systemic
Drug class:
selective serotonin reuptake inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
BuSpar 6.0 551 reviews for BuSpar to treat Anxiety Rx B N X
Generic name:
buspirone systemic
Drug class:
miscellaneous anxiolytics, sedatives and hypnotics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
escitalopram 7.4 1619 reviews for escitalopram to treat Anxiety Rx C N X
Generic name:
escitalopram systemic
Brand name:
Lexapro
Drug class:
selective serotonin reuptake inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
gabapentin Off-label 7.9 492 reviews for gabapentin to treat Anxiety Rx C N X
Generic name:
gabapentin systemic
Drug class:
gamma-aminobutyric acid analogs
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
diazepam 8.3 496 reviews for diazepam to treat Anxiety Rx D 4 X
Generic name:
diazepam systemic
Brand names:
Valium, Diazepam Intensol
Drug class:
benzodiazepines, benzodiazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
propranolol Off-label 7.3 387 reviews for propranolol to treat Anxiety Rx C N X
Generic name:
propranolol systemic
Drug class:
non-cardioselective beta blockers, group II antiarrhythmics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
Valium 8.6 208 reviews for Valium to treat Anxiety Rx D 4 X
Generic name:
diazepam systemic
Drug class:
benzodiazepines, benzodiazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
bupropion Off-label 6.0 183 reviews for bupropion to treat Anxiety Rx C N X
Generic name:
bupropion systemic
Drug class:
miscellaneous antidepressants, smoking cessation agents
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
Cymbalta 6.4 309 reviews for Cymbalta to treat Anxiety Rx C N X
Generic name:
duloxetine systemic
Drug class:
serotonin-norepinephrine reuptake inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Vistaril 5.5 197 reviews for Vistaril to treat Anxiety Rx N N X
Generic name:
hydroxyzine systemic
Drug class:
miscellaneous anxiolytics, sedatives and hypnotics, antihistamines
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
trazodone Off-label 6.6 138 reviews for trazodone to treat Anxiety Rx C N X
Generic name:
trazodone systemic
Drug class:
phenylpiperazine antidepressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
Effexor XR 7.0 243 reviews for Effexor XR to treat Anxiety Rx C N X
Generic name:
venlafaxine systemic
Drug class:
serotonin-norepinephrine reuptake inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
duloxetine 6.4 413 reviews for duloxetine to treat Anxiety Rx C N X
Generic name:
duloxetine systemic
Brand name:
Cymbalta
Drug class:
serotonin-norepinephrine reuptake inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
clonidine Off-label 7.1 97 reviews for clonidine to treat Anxiety Rx C N X
Generic name:
clonidine systemic
Drug class:
antiadrenergic agents, centrally acting
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
mirtazapine Off-label 6.7 558 reviews for mirtazapine to treat Anxiety Rx C N X
Generic name:
mirtazapine systemic
Drug class:
tetracyclic antidepressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
Paxil 7.3 274 reviews for Paxil to treat Anxiety Rx D N X
Generic name:
paroxetine systemic
Drug class:
selective serotonin reuptake inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
venlafaxine 6.6 425 reviews for venlafaxine to treat Anxiety Rx C N X
Generic name:
venlafaxine systemic
Brand name:
Effexor XR
Drug class:
serotonin-norepinephrine reuptake inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
paroxetine 7.2 383 reviews for paroxetine to treat Anxiety Rx D N X
Generic name:
paroxetine systemic
Brand names:
Paxil, Paxil CR
Drug class:
selective serotonin reuptake inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Alprazolam Intensol 8.0 8 reviews for Alprazolam Intensol to treat Anxiety Rx D 4 X
Generic name:
alprazolam systemic
Drug class:
benzodiazepines
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
lamotrigine Off-label 7.3 123 reviews for lamotrigine to treat Anxiety Rx C N X
Generic name:
lamotrigine systemic
Drug class:
triazine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
tramadol Off-label 9.3 116 reviews for tramadol to treat Anxiety Rx C 4 X
Generic name:
tramadol systemic
Drug class:
Opioids (narcotic analgesics)
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
Tranxene 9.6 18 reviews for Tranxene to treat Anxiety Rx N 4 X
Generic name:
clorazepate systemic
Drug class:
benzodiazepines
For consumers:
dosage, interactions, side effects
atenolol Off-label 7.9 54 reviews for atenolol to treat Anxiety Rx D N X
Generic name:
atenolol systemic
Drug class:
cardioselective beta blockers
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
risperidone Off-label 5.3 73 reviews for risperidone to treat Anxiety Rx C N X
Generic name:
risperidone systemic
Drug class:
atypical antipsychotics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
clorazepate 9.2 52 reviews for clorazepate to treat Anxiety Rx N 4 X
Generic name:
clorazepate systemic
Brand names:
Tranxene, Tranxene T-Tab
Drug class:
benzodiazepines
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Lorazepam Intensol 9.2 5 reviews for Lorazepam Intensol to treat Anxiety Rx D 4 X
Generic name:
lorazepam systemic
Drug class:
benzodiazepines, miscellaneous antiemetics, benzodiazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
amitriptyline / perphenazine 9.6 8 reviews for amitriptyline / perphenazine to treat Anxiety Rx N N X
Generic name:
amitriptyline / perphenazine systemic
Drug class:
psychotherapeutic combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
desvenlafaxine Off-label 7.2 194 reviews for desvenlafaxine to treat Anxiety Rx C N X
Generic name:
desvenlafaxine systemic
Drug class:
serotonin-norepinephrine reuptake inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
Diazepam Intensol 10 3 reviews for Diazepam Intensol to treat Anxiety Rx D 4 X
Generic name:
diazepam systemic
Drug class:
benzodiazepines, benzodiazepine anticonvulsants
For consumers:
dosage, interactions, side effects
doxepin 7.0 46 reviews for doxepin to treat Anxiety Rx N N X
Generic name:
doxepin systemic
Drug class:
miscellaneous anxiolytics, sedatives and hypnotics, tricyclic antidepressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
oxazepam 8.3 61 reviews for oxazepam to treat Anxiety Rx N 4 X
Generic name:
oxazepam systemic
Drug class:
benzodiazepines
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Paxil CR 7.8 16 reviews for Paxil CR to treat Anxiety Rx D N X
Generic name:
paroxetine systemic
Drug class:
selective serotonin reuptake inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
prochlorperazine 2.2 88 reviews for prochlorperazine to treat Anxiety Rx/OTC N N X
Generic name:
prochlorperazine systemic
Brand name:
Compro
Drug class:
phenothiazine antiemetics, phenothiazine antipsychotics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
amitriptyline / chlordiazepoxide 9.8 4 reviews for amitriptyline / chlordiazepoxide to treat Anxiety Rx N 4 X
Generic name:
amitriptyline / chlordiazepoxide systemic
Drug class:
psychotherapeutic combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
chlordiazepoxide 7.7 37 reviews for chlordiazepoxide to treat Anxiety Rx N 4 X
Generic name:
chlordiazepoxide systemic
Drug class:
benzodiazepines
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Loreev XR 9.8 4 reviews for Loreev XR to treat Anxiety Rx D 4 X
Generic name:
lorazepam systemic
Drug class:
benzodiazepines
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
meprobamate 8.5 14 reviews for meprobamate to treat Anxiety Rx N 4 X
Generic name:
meprobamate systemic
Drug class:
miscellaneous anxiolytics, sedatives and hypnotics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
nefazodone Off-label 9.3 42 reviews for nefazodone to treat Anxiety Rx C N X
Generic name:
nefazodone systemic
Drug class:
phenylpiperazine antidepressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
oxcarbazepine Off-label 6.3 40 reviews for oxcarbazepine to treat Anxiety Rx C N X
Generic name:
oxcarbazepine systemic
Drug class:
dibenzazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
phenytoin Off-label 9.5 8 reviews for phenytoin to treat Anxiety Rx D N X
Generic name:
phenytoin systemic
Drug class:
hydantoin anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
trifluoperazine 7.7 11 reviews for trifluoperazine to treat Anxiety Rx N N X
Generic name:
trifluoperazine systemic
Drug class:
phenothiazine antipsychotics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
vilazodone Off-label 6.2 70 reviews for vilazodone to treat Anxiety Rx C N X
Generic name:
vilazodone systemic
Drug class:
miscellaneous antidepressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
cannabidiol 8.0 3 reviews for cannabidiol to treat Anxiety Rx N X
Generic name:
cannabidiol systemic
Drug class:
miscellaneous anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Natural Product Monographs
Compro Rate Add review Rx/OTC N N X
Generic name:
prochlorperazine systemic
Drug class:
phenothiazine antiemetics, phenothiazine antipsychotics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
nadolol Off-label 8.0 3 reviews for nadolol to treat Anxiety Rx C N X
Generic name:
nadolol systemic
Drug class:
non-cardioselective beta blockers
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
Tranxene T-Tab 10 3 reviews for Tranxene T-Tab to treat Anxiety Rx N 4 X
Generic name:
clorazepate systemic
Drug class:
benzodiazepines
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information

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Frequently asked questions

View more FAQ

Topics under Anxiety

Alternative treatments for Anxiety

The following products are considered to be alternative treatments or natural remedies for Anxiety. Their efficacy may not have been scientifically tested to the same degree as the drugs listed in the table above. However, there may be historical, cultural or anecdotal evidence linking their use to the treatment of Anxiety.

Learn more about Anxiety

Care guides

Medicine.com guides (external)

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

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