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Vistaril Side Effects

Generic Name: hydroxyzine

Note: This document contains side effect information about hydroxyzine. Some of the dosage forms listed on this page may not apply to the brand name Vistaril.

For the Consumer

Applies to hydroxyzine: oral capsule, oral suspension, oral syrup, oral tablet

Other dosage forms:

Along with its needed effects, hydroxyzine (the active ingredient contained in Vistaril) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking hydroxyzine:

Incidence not known
  • Chest pain or discomfort
  • cough
  • difficulty with swallowing
  • dizziness
  • fainting
  • fast heartbeat
  • hives, itching, or skin rash
  • irregular or slow heart rate
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • shortness of breath
  • tightness in the chest
  • unusual tiredness or weakness

Get emergency help immediately if any of the following symptoms of overdose occur while taking hydroxyzine:

Symptoms of overdose
  • Decreased awareness or responsiveness
  • drowsiness
  • nausea
  • seizures
  • severe sleepiness
  • vomiting

Some side effects of hydroxyzine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Rare
  • Shakiness in the legs, arms, hands, or feet
  • trembling or shaking of the hands or feet
Incidence not known
  • Dry mouth
  • headache
  • seeing, hearing, or feeling things that are not there

For Healthcare Professionals

Applies to hydroxyzine: compounding powder, intramuscular solution, oral capsule, oral suspension, oral syrup, oral tablet

Nervous system

Very common (10% or more): Drowsiness/somnolence
Common (1% to 10%): Headache
Uncommon (0.1% to 1%): Dizziness, attention disturbance
Rare (less than 0.1%): Tremor, convulsions
Frequency not reported: Psychomotor impairment, paresthesia, extrapyramidal effects, seizure, coma, ataxia, slurred speech, bitter taste in mouth, faintness, vertigo
Postmarketing reports: Sedation, dyskinesia/involuntary motor activity[Ref]

Gastrointestinal

Common (1% to 10%): Dry mouth
Uncommon (0.1% to 1%): Constipation, nausea
Frequency not reported: Increased gastric reflux, diarrhea, epigastric pain, increased GI peristalsis
Postmarketing reports: Vomiting[Ref]

Other

Common (1% to 10%): Fatigue
Uncommon (0.1% to 1%): Asthenia
Frequency not reported: Lassitude, weakness, tinnitus, labyrinthitis, chills
Postmarketing reports: Malaise, pyrexia[Ref]

Psychiatric

Uncommon (0.1% to 1%): Insomnia
Frequency not reported: Sleep disturbances, depression, increased anxiety, nightmares, irritability
Postmarketing reports: Agitation, confusion, disorientation, hallucinations[Ref]

Cardiovascular

Frequency not reported: Palpitations, flushing, chest tightness
Postmarketing reports: QT interval prolongation, Torsade de Pointes and other ventricular arrhythmias, tachycardia, hypotension[Ref]

Dermatologic

Frequency not reported: Hair loss, eczema
Postmarketing reports: Pruritus, rash (erythematous, maculo-papular), urticaria, dermatitis, angioneurotic edema, increased sweating, fixed drug eruption, acute generalized exanthematous pustulosis, erythema multiforme, Stevens-Johnson syndrome[Ref]

Genitourinary

Frequency not reported: Dysuria
Postmarketing reports: Urinary retention[Ref]

Endocrine

Frequency not reported: Priapism, impotence, early menses[Ref]

Hematologic

Frequency not reported: Blood disorders (agranulocytosis, leucopenia, hemolytic anemia, thrombocytopenia)[Ref]

Hepatic

Frequency not reported: Liver dysfunction
Postmarketing reports: Abnormal liver function tests[Ref]

Metabolic

Frequency not reported: Prophyria, anorexia[Ref]

Hypersensitivity

Frequency not reported: Angioedema
Postmarketing reports: Allergic reaction, hypersensitivity reaction, anaphylactic shock[Ref]

Musculoskeletal

Frequency not reported: Myalgia[Ref]

Ocular

Postmarketing reports: Accommodation disorder, blurred vision[Ref]

Respiratory

Frequency not reported: Thickened respiratory tract secretions, wheezing, nasal stuffiness, throat dryness
Postmarketing reports: Bronchospasm[Ref]

References

1. "Product Information. Vistaril (hydroxyzine)." Pfizer US Pharmaceuticals, New York, NY.

Some side effects of Vistaril may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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