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Vistaril Side Effects

Generic Name: hydroxyzine

Note: This document contains side effect information about hydroxyzine. Some of the dosage forms listed on this page may not apply to the brand name Vistaril.

For the Consumer

Applies to hydroxyzine: oral capsule, oral suspension, oral syrup, oral tablet

Other dosage forms:

Along with its needed effects, hydroxyzine (the active ingredient contained in Vistaril) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking hydroxyzine:

Incidence Not Known

  • Chest pain or discomfort
  • cough
  • difficulty with swallowing
  • dizziness
  • fainting
  • fast heartbeat
  • hives, itching, or skin rash
  • irregular or slow heart rate
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • shortness of breath
  • tightness in the chest
  • unusual tiredness or weakness

Get emergency help immediately if any of the following symptoms of overdose occur while taking hydroxyzine:

Symptoms of Overdose

Some side effects of hydroxyzine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Rare

  • Shakiness in the legs, arms, hands, or feet
  • trembling or shaking of the hands or feet

Incidence Not Known

  • Dry mouth
  • headache
  • seeing, hearing, or feeling things that are not there

For Healthcare Professionals

Applies to hydroxyzine: compounding powder, intramuscular solution, oral capsule, oral suspension, oral syrup, oral tablet

Nervous system

Very common (10% or more): Drowsiness/somnolence

Common (1% to 10%): Headache

Uncommon (0.1% to 1%): Dizziness, attention disturbance

Rare (less than 0.1%): Tremor, convulsions

Frequency not reported: Psychomotor impairment, paresthesia, extrapyramidal effects, seizure, coma, ataxia, slurred speech, bitter taste in mouth, faintness, vertigo

Postmarketing reports: Sedation, dyskinesia/involuntary motor activity[Ref]

Gastrointestinal

Common (1% to 10%): Dry mouth

Uncommon (0.1% to 1%): Constipation, nausea

Frequency not reported: Increased gastric reflux, diarrhea, epigastric pain, increased GI peristalsis

Postmarketing reports: Vomiting[Ref]

Other

Common (1% to 10%): Fatigue

Uncommon (0.1% to 1%): Asthenia

Frequency not reported: Lassitude, weakness, tinnitus, labyrinthitis, chills

Postmarketing reports: Malaise, pyrexia[Ref]

Psychiatric

Uncommon (0.1% to 1%): Insomnia

Frequency not reported: Sleep disturbances, depression, increased anxiety, nightmares, irritability

Postmarketing reports: Agitation, confusion, disorientation, hallucinations[Ref]

Cardiovascular

Frequency not reported: Palpitations, flushing, chest tightness

Postmarketing reports: QT interval prolongation, Torsade de Pointes and other ventricular arrhythmias, tachycardia, hypotension[Ref]

Dermatologic

Frequency not reported: Hair loss, eczema

Postmarketing reports: Pruritus, rash (erythematous, maculo-papular), urticaria, dermatitis, angioneurotic edema, increased sweating, fixed drug eruption, acute generalized exanthematous pustulosis, erythema multiforme, Stevens-Johnson syndrome[Ref]

Genitourinary

Frequency not reported: Dysuria

Postmarketing reports: Urinary retention[Ref]

Endocrine

Frequency not reported: Priapism, impotence, early menses[Ref]

Hematologic

Frequency not reported: Blood disorders (agranulocytosis, leucopenia, hemolytic anemia, thrombocytopenia)[Ref]

Hepatic

Frequency not reported: Liver dysfunction

Postmarketing reports: Abnormal liver function tests[Ref]

Metabolic

Frequency not reported: Prophyria, anorexia[Ref]

Hypersensitivity

Frequency not reported: Angioedema

Postmarketing reports: Allergic reaction, hypersensitivity reaction, anaphylactic shock[Ref]

Musculoskeletal

Frequency not reported: Myalgia[Ref]

Ocular

Postmarketing reports: Accommodation disorder, blurred vision[Ref]

Respiratory

Frequency not reported: Thickened respiratory tract secretions, wheezing, nasal stuffiness, throat dryness

Postmarketing reports: Bronchospasm[Ref]

References

1. "Product Information. Vistaril (hydroxyzine)." Pfizer US Pharmaceuticals, New York, NY.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

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