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User Reviews for Venlafaxine to treat Anxiety

Also known as: Effexor, Effexor XR

Venlafaxine has an average rating of 6.5 out of 10 from a total of 375 ratings for the treatment of Anxiety. 58% of reviewers reported a positive experience, while 28% reported a negative experience.

Venlafaxine rating summary

6.5/10 average rating

375 ratings from 396 user reviews.

Compare all 141 medications used in the treatment of Anxiety.

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12%
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Reviews for Venlafaxine

Sarah · January 28, 2021

Effexor XR (venlafaxine): “I have severe anxiety and regular depression from time to time. I’ve taken Lexapro, Prozac, and Zoloft. They eventually quit working for me. I had so much anxiety after work that I would like to have an alcoholic drink and sometimes a cigarette to calm my nerves. The problem with this is because alcohol makes anxiety worse if you drink more than two drinks. So it was an endless cycle. I was also getting to the point where I couldn’t get off the couch and had no motivation to do anything, Taking a shower was hard for me. I was sleeping a lot!!! Start out on theEffexor XR 37.5mg dose for about a week or two before moving up to 75 mg. At first it made me feel really weird, my mind would race and I was having a hard time sleeping. I stuck it out! I am now taking 75 mg and I’m so much better! I get up at 6:00 am when I used to sleep until 9:00. I go to the gym 3 days a week, I get dressed up and now I have a part time job. Effexor has literally changed my life!!”

10 / 10
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ks · Taken for 6 months to 1 year · August 23, 2020

Effexor XR (venlafaxine): “If you are reading these reviews and having anxiety about taking a medicine I get it. The best advice I can offer is go into with a mindset that this is going to help you. In the scariest time of my life when I had panic disorder, was having trouble eating and sleeping Effexor saved me. I took Lexapro terrified to take it and had horrible reactions. This drug makes me feel like myself minus panicking. I didn't feel like it kicked in until about 3 months. The only thing is it does make you feel a like more "flat" but I was a little over emotional so it helped with this. I've been on this for almost a year and would recommend trying it.”

8 / 10
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Sara Jane · Taken for 1 to 6 months · March 14, 2020

Effexor XR (venlafaxine): “Effexor is helping me calm down and it’s helping my relationship with my boyfriend. I got put on it for my agitation, irritability , anxiety, social anxiety. I no longer am snappy and argumentative. I know people say it’s hard to withdraw off but it’s saving my life and I plan to stay on it for a long time. Thumbs up”

10 / 10
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Cleveland · March 2, 2021

Effexor XR (venlafaxine): “I’ve had depression anxiety my whole life and I’m diagnosed major depression and generalized anxiety disorder. I tried all the other antidepressants didn’t really know if they worked or not, new Dr. slowly tapered me up on Effexor. That was about a year ago... The side effects weren’t terrible some nausea and insomnia for like a week and then after that the side effects were gone. I feel so much better honestly and I’m not just saying that because the Lexapro and Cymbalta I never knew if they were working or not. This helps with my anxiety a lot and rumination and also this is the first winter I’ve enjoyed in at least a decade. Also I have an eight-year-old four-year-old and three-month-old all girls and virtual schooling is still on, so it definitely helps me be more patient And takes the edge off so I don’t yell and scream in a fit of exasperation. I was also afraid of getting postpartum but I honestly haven’t felt any of that thank the Lord.”

9 / 10
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Panic guy · March 22, 2021

Effexor XR (venlafaxine): “Since my middle east deployment I've dealt with panic attacks. It got to the point I was severely agoraphobia, not even able to leave my home to drive to the gas station a mile away. VA SSRIs never worked. After being drug to the local ER due to severe brain fogginess, ER physician suggested norepinephrine might be the issue, not the serotonin. Dr also took it and said to give Effexor XR a go. 3 weeks later I believe he may be right. I no longer am focusing on every little beat my heart makes. I can drive again. I can go places. I'm not perfect yet but major improvements have happened. Fogginess is still there a tad bit but not nearly as horrible as it was 3 weeks ago. It's not even fully in my system yet. If you have taken all the SSRIs there are with no results, try this. It works. I've heard withdrawals are real bad but I'm not worried about that right now. It just feels good to feel a bit more normal again. Praise God. P.S. I'm still able to "perform" with the wife. Another huge relief.”

9 / 10
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aimeejuniper · February 25, 2020

Effexor XR (venlafaxine): “I'm a 27 y/o female, good health but have GAD and MDD. I began taking Effexor XR when I began having panic attacks while driving. I began with 37.5mg for 4 weeks, then upped to 75mg after that. After 3 months, I began to sweat in my sleep despite not feeling overheated. I began to suffer from sexual dysfunction, lost my libido and had difficulty reaching an orgasm (neither had been an issue previously). My appetite increased and I gained 25lbs in 1 year. I also noticed I felt very "flat" emotionally. I wrote this because I feel like positive reviews are lacking. Effexor absolutely improved my anxiety. The side effects were unpleasant but not severe. Stopping this medication suddenly can cause withdrawal symptoms, so when I switched to a new one, I slowly tapered off it by opening the capsule and counting the granules, reducing them by about 4 per day. I did not suffer from any "brain zaps" or any withdrawal symptoms.”

8 / 10
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Ypiscis · Taken for less than 1 month · May 31, 2018

Effexor XR (venlafaxine): “Hello everyone. Ok I posted May 19 and this is my update. So I stopped sertraline and started taking Effexor 75 mg capsules. The Doctor advise to stop sertraline slowly so the first week I took Effexor 75 mg and half of sertraline which is 50 mg. The second week I took Effexor 75 mg and setraline 25 mg. And now just Effexor . And now just 75 mg of Effexor (venlafaxine ) . I feel so much better . My anxiety has almost stopped and I remind my self to take deep breaths . I'm sleeping better and I’m pushing my self lot more. I refuse to sleep during the day and all that is helping me. I’m posting this because I know how it feels to feel helpless. So everyone keep pushing through this. Keep your head up, keep praying and keep positive. Love you all and good luck!!!!”

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Frequently asked questions

Mitra_ · August 9, 2014

Effexor XR (venlafaxine): “Have suffered from bouts of severe anxiety over the last few years that would leave me bedridden, suicidal, unable to work or eat. Tried Zoloft, Celexa, Lexapro, Cymbalta, Luvox and honestly thought nothing would ever work for me. All made me worse. Psych doctor wanted to try Effexor XR but I was worried about the withdrawing from it - after trying everything else I finally agreed. Has taken a month to feel a difference. I'm enjoying things again, not chewed up by horrible anxiety, I'm actually HAPPY?! 1st month on it was so challenging - very low, anxious, exhausted, nauseous. But now no side effects. I feel like a light's gone on. Like I am getting my life back. I could sob with relief. Truly believed I'd never get better, but here I am.”

8 / 10
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Anonymous · Taken for 1 to 2 years · September 4, 2014

Effexor XR (venlafaxine): “Have been on Effexor xr 75mg for about 1 year now for anxiety & panic attacks. I had a constant odd pain in my stomach (like butterflys and hunger). I would sweat uncontrollably & get dizzy & faint if I was put in a situation I wasn't comfortable with. I went to a Dr. who diagnosed me with anxiety and put me onto Effexor. The first 3 days were hell, every bad review I read on Google I could relate to, I even ended up going to the ER one night as I felt so nauseous and felt like I was losing control and could not stop freaking out. The Dr told me to stick to it, and promised it would get better. I'm so glad I did. I feel that this medication has saved me. I can almost live a normal life again.”

9 / 10
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THISCHANGEDMYLIFEFORTHEBETTER · July 27, 2017

Effexor XR (venlafaxine): “First off, I want to say I never take the time to write reviews however I do end up myself reading everyone else's so I hope this helps someone! I'm 22 Female, and for about 4 years suffered from anxiety. First it started off as panic anxiety then with failure of trying medications Prozac, Zoloft, and lexapro, my head was just so much worse. I could feel the chemical imbalance I began getting daily depression and anxiety to the point I'd worry 24/7. It ruined relationships & made me seem crazy. I finally got on Effexor last month. CHANGED MY LIFE. I feel NORMAL again. Happy, no anxiety, energetic. Only side effects were yawning, vivid dreams, & at first jaw pain. I highly suggest this with panic/daily anxiety/depression mix! My fears are gone”

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Happy in Canada · Taken for 10 years or more · March 10, 2014

Effexor XR (venlafaxine): “I have been on Effexor for the past 10 years - I started having panic attacks as a child although I didn't know at the time what was going on - when I was 17 the doctor prescribed Valium that I took periodically when my anxiety got really bad - finally when I was 40 the doctor suggested I go on a very low dosage of Effexor (37.5mg) because he was sure I had generalized anxiety disorder - what a difference this has made in my life - felt"weird" the first few weeks but now I have very little anxiety and really no side effects except maybe lower libido. I had no idea how much anxiety I had been living with all my life.”

9 / 10
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ATTORNEYSA · Taken for 1 to 6 months · July 29, 2019

Effexor XR (venlafaxine): “I have been on Effexor for just over a month and I can say that I'm rather surprised. I am a 25 year old male, who has been on antidepressants for almost 12 years (unfortunately I was diagnosed with depression and a social anxiety disorder at a very young age). Prior to being prescribed Effexor - I was on zoloft for a few years. Zoloft worked, but as time went on, started to loose it's effectiveness. With Effexor I have more energy and feel that I can get through the day. I hope this medicine continues to work for anyone suffering <3”

8 / 10
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STEEL · Taken for 1 to 6 months · April 17, 2019

Effexor XR (venlafaxine): “I owe a great thank you to Effexor. My cons are vivid dreaming and minor sleep difficulties. But the pros for myself, outweigh the bad. For the first time in 10+ years my anxious thoughts and sweats are almost nonexistent. I enjoy the taste of food again. And I feel like I have more purpose, I don’t walk around with the “I’m just here, useless” cloud over me. I will continue to fight to feel right, Effexor has definitely gave me my footing.”

9 / 10
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Jon Sullivan · Taken for 1 to 6 months · September 6, 2016

Effexor XR (venlafaxine): “I told myself I'd come back and write a review if I liked Effexor, because people tend to only write reviews if they don't like it, and that's scary for someone who is trying to figure out whether to try it or not. This was the first medication I've tried to treat my chronic GAD. Before Effexor, I was living in a state of constant panic and anxiety. It was really awful, and I felt like I couldn't continue much longer without completely breaking down. I'm now 3 months in, and it has helped so much. I am still myself and I have anxious thoughts, but there is no longer that sense of panic and overwhelming fear. I feel like I did pre-anxiety and its wonderful. Everyone reacts differently, but have hope! Medication can work!”

9 / 10
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0521j0929d · January 26, 2015

Effexor XR (venlafaxine): “I have been on Effexor XR for about a year, after switching from Paxil. It is a scary thing to read all these reviews, and question about whether you should or should not take it. I personally started for anxiety, and it has helped tremendously. To me having panic attacks is not a fun task, yes are there side effects but everything you put into your body does. Please try what your doctor recommends before you read all the reviews.”

10 / 10
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K · Taken for 2 to 5 years · April 19, 2020

Effexor XR (venlafaxine): “I knew my IBS was directly affected by my anxiety and depression, so I went to a doctor to be put on meds to help with that. Effexor worked wonders! I was able to put back on the 40lbs. I had lost from being sick ALL the time. And zero panic attacks. It's not as good at helping my depression, but it is noticeably better still. The only issue I have with it is that it absolutely WRECKS my stomach if I miss even a single dose, so I have to be really careful about that. But I mean, it's made my life so much more liveable that I consider that a small issue.”

9 / 10
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momof4minions · August 22, 2017

Effexor XR (venlafaxine): “I started Effexor XR (generic version) about 3 weeks ago. I will admit, the bottle sat on my counter for a week before I took my first one, because the negative reviews terrified me. I finally took one and I am so glad I did! I have been on practically every anxiety/ depression med there is and had kind of lost hope with them working. I have also tried several different natural methods and they helped a little bit, but not nearly enough. I struggle mainly with anxiety and have for about 15 years now. By day 3, I had already noticed a difference. It's been 3 weeks & not only is my anxiety significantly better, I no longer have swollen joints or numbness in my hands & feet, I'm so much happier & way less stressed. Life changing!!”

10 / 10
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Anonymous · Taken for 1 to 2 years · February 12, 2020

Effexor XR (venlafaxine): “I’ve tried many different drugs for anxiety and depression, the last being Lexapro which did nothing to help me. Gave Effexor a try and I’ve noticed a big difference. I’m able to go out in public more without getting anxious, I rarely get depressed, and my mood has improved tremendously. No side effects. Just be careful to take it every single day and don’t miss a dose; my nurse practitioner said people feel terrible if they do”

10 / 10
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SSKirby · Taken for 1 to 6 months · March 13, 2014

Effexor XR (venlafaxine): “I have been on Effexor XR 75mg for two months now, after previously being on Zoloft and Celexa. The two other medications were not effective for my anxiety and depression, and they tended to make me either tired or foggy regardless of the time of day that I took them. I expected the tiredness to wear off, but the foggy feeling never did. My doctor prescribed Effexor XR, and it has been very effective for both my depression and anxiety symptoms. I am not 100% perfect, and I still have anxiety, but in the appropriate moments. The moments of unreasonable anxiety attacks are fewer and far between since starting the medicine. I had no negative side effects, and I take it every morning at 9am.”

9 / 10
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Downout · Taken for less than 1 month · August 8, 2014

Effexor XR (venlafaxine): “I have suffered with major depression my whole adult life. Have been on several types of antidepressants all of which left me feeling like a zombie. The first time I took Effexor I noticed a major swing in my moods it has been a total saviour for me. Two weeks ago I was in bad shape, today a week of Effexor I feel on top of the world . This medication with the help of family friends and councilor had without a doubt totally turned my life around now everything in my life is happy and positive. Without this medication my future would've been bleak to say the least.”

10 / 10
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Atexun · May 7, 2015

Effexor XR (venlafaxine): “Started on 37.5mg for a month. First two days were only side effects - I was a little jumpy, couldn't keep legs still, and had insomnia. That went away in 48 hours. Then it shifted to making me sleepy and fairly relaxed. However, I still had breakthrough anxiety crying and didn't feel much change in depression. Decided to up the dose and have been at 75mg for a while now. No side effects. This dose has obliterated my anxiety and helped with depression. All I feel is calm and relaxed. I am more outgoing and happy. Only thing I noticed, like so many others, is that it is tough to miss a dose. But, don't let that dissuade you from trying it. It really has been a miracle for me.”

10 / 10
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Sonjatx1 · Taken for 1 to 6 months · May 1, 2015

Effexor XR (venlafaxine): “I have had anxiety and depression for years. Was on all different types of medicines. Even got so badly depressed and anxious that I was bedridden for almost 1 year. I got switched to Effexor and in a few days felt great! I cannot believe I spent all these years in darkness! This is the best medicine ever for me! I am not depressed and zero anxiety! I just wish I would have been on it earlier.”

10 / 10
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Stixie K · October 14, 2016

Effexor XR (venlafaxine): “I cannot describe how life changing this medication has been for me. I've been suffering from anxiety/depression, specifically social anxiety and low self esteem, my whole life. It was at a point where I thought it was normal to be negative, pessimistic, anxious and depressed all the time. I tried EVERYTHING including therapy, exercise, diet and an array of medicines and nothing worked. I nearly developed an addiction to Xanax just trying to combat the anxiety. Prozac, lexapro, Concerta, stratera; Nothing worked. Finally got introduced to Effexor XR. Started on 75mg for 2 months, I wasn't that satisfied. I got put on 150mg for 2 months then. CANNOT BELIEVE THE DIFFERENCE. I'm happy, confident and positive. AMAZING. Long may it last.”

10 / 10
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starsoul50 · Taken for less than 1 month · August 27, 2014

Effexor XR (venlafaxine): “I've suffered severe anxiety/panic attacks my entire life. I've had Xanax, Valium, Prozac and Edronax over the cause of my years. I finally changed doctor, came off everything, to start where I'm at now. I began on 37.5mg over two weeks ago and noticed a difference straight away. Now on 75mg and getting better every single day. My panic attacks could cause me to pass out, so this is a huge leap in health for me. For those concerned about coming off Xanax, it's so worth the effort. I now feel like I'm getting my life back and I'm truly grateful.”

9 / 10
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Pisces90 · Taken for 1 to 6 months · March 19, 2013

Effexor XR (venlafaxine): “Effexor Saved Me After Many Failed Medicines. Current Med Combo- Effexor 75 mg, Lamictal 200 mg, Abilify 5 mg It saved me from wasting anymore time locked up in my house 24/7 and avoiding conversations, knocks at the door, people, telephone calls, and anything else involving socializing. I FINALLY LEAVE MY HOUSE. WILLINGLY and REGULARLY. Daily. I NO LONGER FEAR APPLYING FOR JOBS. I NO LONGER FEAR THE POSSIBILITY OF HAVING A JOB because I would have to deal with people. I am willing and eager to go out with friends, family, acquaintances, meet new people. SIDE EFFECTS- Only Nightmares, which eventually become less and less and then go away after 2 months. Maybe a little unpleasant at first. Definitely bearable. It's not bad for everyone.”

10 / 10
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This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.