Venlafaxine Alternatives Compared
Venlafaxine | Vortioxetine | Vraylar (cariprazine) |
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Venlafaxine | Vortioxetine | Vraylar (cariprazine) |
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Prescription only
Venlafaxine is an antidepressant that may also be used for mood disorders and off-label for some other conditions such as hot flashes. It may cause a discontinuation syndrome if abruptly stopped... View more |
Prescription only
Vortioxetine may be used to treat depression in adults. It is different from other antidepressants currently on the market because it directly affects serotonin receptors as well as inhibits... View more |
Prescription only
Vraylar is an atypical antipsychotic that is effective for the treatment of schizophrenia and bipolar disorder. Vraylar is usually well-tolerated and less likely than some other antipsychotics to... View more |
Related suggestions Major Depressive Disorder
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More about Venlafaxine | More about Vortioxetine | More about Vraylar (cariprazine) | |
Ratings & Reviews | |||
Venlafaxine has an average rating of 6.5 out of 10 from a total of 2777 ratings on Drugs.com. 54% of reviewers reported a positive effect, while 27% reported a negative effect. |
Vortioxetine has an average rating of 6.1 out of 10 from a total of 1546 ratings on Drugs.com. 48% of reviewers reported a positive effect, while 32% reported a negative effect. |
Vraylar has an average rating of 6.0 out of 10 from a total of 509 ratings on Drugs.com. 49% of reviewers reported a positive effect, while 34% reported a negative effect. |
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Drug Class | |||
Side Effects | |||
Generic Availability | |||
Lower cost generic |
N/A |
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Pricing and Coupons * Prices are without insurance | |||
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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Dosage Forms Available | |||
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N/A |
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Brand Names | |||
Effexor, Effexor XR | Trintellix |
N/A |
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Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||
4 hours |
66 hours |
504 hours |
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CSA Schedule ** View glossary of terms | |||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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Drug Interactions | |||
A total of 695 drugs are known to interact with Venlafaxine:
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A total of 352 drugs are known to interact with Vortioxetine:
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A total of 571 drugs are known to interact with Vraylar:
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Alcohol/Food/Lifestyle Interactions | |||
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Disease Interactions | |||
First Approval Date | |||
December 28, 1993 |
September 30, 2013 |
September 17, 2015 |
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WADA Class View World Anti-Doping Agency classifications. | |||
N/A |
N/A |
N/A |
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More Information | |||
Patient resources | |||
Professional Resources | |||
Related Treatment Guide | |||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.