User Reviews for Nefazodone to treat Anxiety
Nefazodone has an average rating of 9.3 out of 10 from a total of 38 reviews for the off-label treatment of Anxiety. 92% of reviewers reported a positive experience, while 5% reported a negative experience.
Reviews for Nefazodone
"Been taking Serzone / Nefazadone since 1996 for panic , anxiety disorder. I have tried every other antidepressant on the market and NOTHING else worked ! I tried several anti-depressants Now after battling cancer and losing my girlfriend to cancer , my mother to cancer and my best friend to a massive heart attack - Here I am again 10 months later suffering due to lack of my med. Try this pill, that pill , this pill , that pill - NOTHING IS WORKING !! I NEED MY NEFAZADONE BACK !! PLEASE BRING THIS DRUG BACK TO MARKET !! WE ARE SUFFERING HERE"
"Contact the FDA drug shortage site, email address is available online. Ask them to find another company willing to manufacture this medication. They have the contacts, knowledge and know who to contact , plus it is their job! This is a medically necessary medication"
"I am a physician. I have been on this medication for over 20 years. Nothing else worked and during the shortage I was struggling significantly. This medication not only saved my career, but also my life. Unique and highly effective, nefazodone needs to stay on the market."
"I was on Nefazodone for 26 years after trying several other antidepressants that had side effects. It had no side effects and made me feel like myself again. Now that it been unavailable for almost a year I have had to go off of it while starting Trazodone. I have been off of Nefazodone for a month and on Trazodone for 2 months. I am anxious, depressed, scared and cry everyday. I am hoping the Trazodone will start working since it is the closest thing to Nefazodone. I have been going up in 25 mg increments since starting it. I don't want to have to try something else. I am outraged at Teva. Apparently they don't care about us. I believe that Nefazodone is or was used by so few people that it wasn't worth their while to make it. Back in April I tried calling, writing Teva and the FDA and got nowhere. I am praying it will be made again, but I don't know how difficult it would be to transition back."
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"As of 12/20/21 nefazodone is out of shortage and again available. I was finally able to fill my prescription on 12/27/21. This medication has been so helpful for me. I tried many others and this seems to be the only one that along with controlling the depression also keeps my anxiety in check. I have been on this for over 20 years."
"This drug changed my whole life. Suffering from anxiety depression, it did not feel or look like depression; nevertheless it was. Mostly this expressed in anxiety, especially new events or chores, not to mention jobs or large changes. Within 4 weeks, the Psychiatrist asked me if it was helping; I wasn't sure, but, within 8, I told him, "I feel like...me!" That was 20 YEARS ago. It still works and, no, that is not an illusion. I have tried to gently go off several times under doctor's care, and always return to my unsettled state of fear. I have had a successful career and personal life, am healthy and content. Nefazodone save me."
"A close friend of mine and I have been on nefazadone 50mg for 20+ years. It has been a life saver.we cannot tolerate any other anti depressant or anti anxiety medication. Now we are experiencing a shortage of the 50’s. Wondering if we can group together to let Teva know that we depend on this drug. I called Teva to find out the availability but all the representative would say is there is an ingredient that has been difficult to obtain to make nefazadone . She would not give me anymore information. Wondering if we group together and let Teva know how important and necessary this drug is to us. Don’t know how to get this going. Please help."
Serzone (nefazodone) "I have been using Serzone and the generic versions for over 15 years now. When the brand was pulled from the market, I tried Wellbutron, Celexa and Prozac. All three had horrible side effects and I finally found a doctor who would prescribe me the generic of Serzone again. This medication keeps me on an even keel, keeps the anxious thoughts from overwhelming me and helps me sleep at night. My liver panels are always perfect and my only side effect is that I have to take it right before I go to bed as it makes me sleepy."
"Teva NEEDS to get its act together and get this drug back on the market! I have taken this off-label for OCD for 12 years and it is the *only* thing that works for me. My psych put me on Trazodone after I ran out of Nefazodone and it is not even close to the same thing. I'm close to quitting my job because my condition is degenerating so badly. Before Nefazodone I tried every SSRI and tricyclic in the book and nothing worked. My psych made sure I understood the (tiny) risk when he put me on Nefazodone. Teva, please please PLEASE fix this, real people are suffering!"
"After trying several antidepressants and anti anxiety meds my psychiatrist gave me Nefazadone. It saved my life! I went from having almost daily panic attacks to none. Severe depression to mild at times. I got my life back and was able to function! This was 20 years ago and still doing well. This is a unique medication and usually works when others fail. My only side effect was some visual effects for about 3 months. There has been a shortage recently but now it’s back and I am so grateful! If your dr. is concerned about liver problems do not be discouraged! Unfortunately this drug got a bad rap from its brand name serzone years ago. It is no more dangerous than many other antidepressants and medications on the market including Tylenol. Hope this helps someone like it did me."
"Very Important to contact Teva and the FDA drug shortage department. Web addresses are listed online. EMAIL THEM, share your experience with this medication and ask them for their help. And continue to ask for them their help! An email can be forwarded to the right people. And yes, also continue to call, too! Everyone needs to help us get this resolved. Stay persistent!"
"I have depression and OCD. Nefazodone (Serzone) changed my life. The chains of OCD and depression fell off within 2 months of starting this medicine. This medication was an answer to prayer. I have been off and on SSRIs but they did not help much. Paxil was the only medication that helped my OCD but the side effects were bad. I have not experienced any sexual side effects, weight gain, or fatigue with Nefazodone. Its been a wonder drug for me."
"I had debilitating anxiety and was prescribed Nefazodone. I have experienced no side affects as far as I can tell and almost perfect relief. I'm back to normal. I only need 100 mg a day. When I'm very stressed I sometimes have to take another 50 mg."
"This medication literally saved my life. It is unlike all other antidepressants. The other antidepressants I tried, and there were many of them, actually increased my anxiety. I would wake up with fear, terrible fear each morning after another sleepless night and it just got worse from there. This r/x might not work for you, we do not share the same body chemistry, but I assure you, if it does, you'll want to live again."
"I’ve been taking Nefazodone for 15 years. It’s the best medication for anxiety and depression without side effects. So happy to have it back. If anyone is having difficulty finding a pharmacy that carries it or need support then join on Facebook Nefazodone Shortage Survivors and Support."
"I have been on serzone/Nefazadone for 23 years. My psychiatrist had told me about it, that it could cause liver problems but so could many other drugs and meds in same class. Thought it got a bad wrap from few law suits. Advised labs yearly to have peace of mind. Never had any liver problems. This medicine saved my life. I had depression and daily panic attacks. Could not hardly function. No life. I was at the point of giving up. So many medications did not work. I’m still amazed how well this medicine worked for me. I was told by psychiatrist it was one of the best medications he has ever prescribed and it was a shame that other drs shy away from it. Hope this helps someone who is struggling and I hope this medicine will help you like it did me."
"I took nefazodone for over 20 years before it became unavailable. I was then put on a combination of effexor and zyprexa in the hopes that it would mimic the efficacy of just nefazodone. It hasn't even come close to helping me feel as good as nefazodone did. I have an appointment in just a few weeks to talk to my medical provider who will hopefully put me back on nefazodone. I LOVE THIS MEDICATION!"
"I took nefazadone for 18 years. Somewhere along the way it stopped working because when I came off the medication I had no withdrawal symptoms. I recently emailed teva and they replied they have no idea when it will be released. Teva was offered to make the drug in the USA and they DECLINED! Teva does not care about patients at all. I was lucky and had no withdrawal. I can't imagine what everyone else is going through. Nefazadone worked amazing when I first started taking it. I actually think from taking it soon it corrected what was wrong in my brain. I will continue to fight for everyone by constantly emailing Teva, the FDA and whoever else I can get to listen to me. I'm concerned that if they bring nefazadone back that this shortage will happen again. Teva restructured the company and shut down several manufacturing plants. I did alot of research."
"I've been taking this medicine since I stopped drinking - 12 years ago! It was the ONLY medicine that ever worked for my panic attacks and depression. I had no idea at the time that they were related. I had been an alcoholic for about 15 years, and had almost given up. A lady at work told me about it - totally by chance, and so I tried it. It worked so well after a few weeks I was able to get outside and function again, and I was able to get off the alcohol. I take it only in the morning and just after eating around lunchtime. If I take it too late in the day, it keeps me awake half the night. My speech has become a little hesitant over the last few years - a rare side effect. But it's manageable and worth the trade-off."
"I have been on this drug for 23 years. Had tried everything else but my depression and anxiety were so terrible I ended up in the mental ward from trying to hurt myself. I Have been to every drug store to get it but now no one has it. Please bring it back or replace it with something Teva. There are many of us that need this!!!!"
"I have taken 500 mg of Nefazodone and Xanax at night for anxiety and insomnia for 25 years. I think it was quite helpful. I have been wanting to take a vacation from it to see if it was still needed, but found the withdrawal unpleasant. It is currently unavailable in the U.S. so I thought, no time like the present to titrate off of it. I’ve been reducing the dose by 175 mg every few weeks. My only withdrawal symptom has been insomnia this time. I am excited to see if it’s no longer needed."
"I have been on this medication for 18 years, and thankful that I found it. It was the only medication I found that would reduce job related stress/anxiety enough to let me sleep decently and not affect sexual function. The only reason I rated this a 7 instead of 10 is because I have developed some tolerance to it (I am at max dose of 600mg). I have had to also take large doses of SAM-E as well, but it does still work. It is still available from at least 1 pharmaceutical company."
"I have been on Nefazodone since 1997 after trying many other medications with terrible results. I have been told it is currently not being produced. Is this a temporary shortage? I do not believe I can exist without it!"
"Nefazadone was a miracle drug for my depression/anxiety. When TEVA stopped production, I switched to trazadone which was not anywhere near as good. I contacted Teva today (4/4/22) and they have started production again !!!!! I immediately made an appointment with my MD to get an Rx for it again !!!!! Unfortunately, it doesn't come in the 200 mg pill strength, though, so I'll probably have to pay more."
Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.
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"Twenty year user. Nefazodone is a miracle drug for me. As others have said, taking nothing was far better than all the other options I tried. I had a 9 month back supply, which is now down to 4 1/2 months. Contacted TEVA, who told me the same thing they told everyone else. One note: TEVA is the one who made the active ingredient. Saying they can't get it is disingenuous. I will have to start tapering soon. I've read quitting the last 25 - 50 mg's is the worst part. I hope to need no substitutes. Bad days ahead, I'm sure."