Hydroxyzine Interactions
There are 581 drugs known to interact with hydroxyzine, along with 9 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 93 are major, 484 are moderate, and 4 are minor.
- View all 581 medications that may interact with hydroxyzine
- View hydroxyzine alcohol/food interactions (1)
- View hydroxyzine disease interactions (9)
Most frequently checked interactions
View interaction reports for hydroxyzine and the medicines listed below.
- Abilify (aripiprazole)
- Adderall (amphetamine / dextroamphetamine)
- Adderall XR (amphetamine / dextroamphetamine)
- Ambien (zolpidem)
- Benadryl (diphenhydramine)
- BuSpar (buspirone)
- Cymbalta (duloxetine)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flexeril (cyclobenzaprine)
- Flonase (fluticasone nasal)
- Klonopin (clonazepam)
- Lamictal (lamotrigine)
- Lexapro (escitalopram)
- Lyrica (pregabalin)
- Metoprolol Succinate ER (metoprolol)
- Prozac (fluoxetine)
- Seroquel (quetiapine)
- Singulair (montelukast)
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D2 (ergocalciferol)
- Vitamin D3 (cholecalciferol)
- Vyvanse (lisdexamfetamine)
- Wellbutrin (bupropion)
- Wellbutrin XL (bupropion)
- Xanax (alprazolam)
- Zofran (ondansetron)
- Zoloft (sertraline)
- Zyrtec (cetirizine)
Hydroxyzine alcohol/food interactions
There is 1 alcohol/food interaction with hydroxyzine.
Hydroxyzine disease interactions
There are 9 disease interactions with hydroxyzine which include:
- depression
- QT prolongation
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- glaucoma
- liver disease
- renal/liver disease
More about hydroxyzine
- hydroxyzine consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (1,407)
- Drug images
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Support group
- Drug class: antihistamines
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Xolair
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Alprazolam
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Duloxetine
Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor antidepressant used to ...
Ondansetron
Ondansetron is used to prevent nausea and vomiting caused by surgery, chemotherapy, or radiation by ...
Escitalopram
Escitalopram is an SSRI antidepressant used to treat major depressive disorder in adults and teens ...
Cyclobenzaprine
Cyclobenzaprine is a muscle relaxant and works by blocking pain sensations. Includes ...
Meloxicam
Meloxicam is a nonsteroidal anti-inflammatory drug used to treat pain or inflammation caused by ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.