Tranxene T-Tab Side Effects
Generic name: clorazepate
Medically reviewed by Drugs.com. Last updated on Apr 12, 2022.
Note: This document contains side effect information about clorazepate. Some of the dosage forms listed on this page may not apply to the brand name Tranxene T-Tab.
More frequent side effects include: irritability. See below for a comprehensive list of adverse effects.
For the Consumer
Applies to clorazepate: oral tablet
Oral route (Tablet)
Risks from concomitant use with opioids; abuse, misuse, and addiction; and dependence and withdrawal reactions:Concomitant use of benzodiazepines and opioids may result in profound sedation, respiratory depression, coma, and death. Reserve concomitant prescribing of these drugs in patients for whom alternative treatment options are inadequate. Limit dosages and durations to the minimum required. Follow patients for signs and symptoms of respiratory depression and sedation.The use of benzodiazepines, including clorazepate, exposes users to risks of abuse, misuse, and addiction, which can lead to overdose or death. Abuse and misuse of benzodiazepines commonly involve concomitant use of other medications, alcohol, and/or illicit substances, which is associated with an increased frequency of serious adverse outcomes. Before prescribing clorazepate and throughout out treatment, assess each patient’s risk for abuse, misuse, and addiction.The continued use of benzodiazepines, including clorazepate, may lead to clinically significant physical dependence. The risks of dependence and withdrawal increase with longer treatment duration and higher daily dose. Abrupt discontinuation or rapid dosage reduction of clorazepate after continued use may precipitate acute withdrawal reactions, which can be life-threatening. To reduce the risk of withdrawal reactions, use a gradual taper to discontinue clorazepate or reduce the dosage.
Side effects requiring immediate medical attention
Along with its needed effects, clorazepate (the active ingredient contained in Tranxene T-Tab) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking clorazepate:
- Bladder pain
- bloody or cloudy urine
- difficult, burning, or painful urination
- frequent urge to urinate
- lower back or side pain
- shakiness and unsteady walk
- slurred speech
- trembling or shaking of the hands or feet
- unsteadiness, trembling, or other problems with muscle control or coordination
Get emergency help immediately if any of the following symptoms of overdose occur while taking clorazepate:
Symptoms of overdose
- Change in consciousness
- loss of consciousness
- mood or mental changes
Side effects not requiring immediate medical attention
Some side effects of clorazepate may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
- Blurred vision
- double vision
- dry mouth
- feeling sad or empty
- loss of appetite
- loss of interest or pleasure
- mental confusion
- nausea or vomiting
- passing of gas
- seeing double
- skin rash
- stomach pain, fullness, or discomfort
- trouble with concentrating
- trouble with sleeping
- unusual tiredness or weakness
For Healthcare Professionals
Applies to clorazepate: oral tablet
The most commonly reported side effect was drowsiness.[Ref]
Frequency not reported: Ataxia, dizziness, drowsiness, headache, nervousness, slurred speech[Ref]
Frequency not reported: Dry mouth, various gastrointestinal complaints[Ref]
Frequency not reported: Blurred vision, diplopia[Ref]
Frequency not reported: Transient skin rash[Ref]
Frequency not reported: Fatigue[Ref]
Frequency not reported: Genitourinary complaints[Ref]
Frequency not reported: Abnormal kidney function tests[Ref]
Frequency not reported: Decreased hematocrit[Ref]
Frequency not reported: Decrease in systolic blood pressure[Ref]
More about Tranxene T-Tab (clorazepate)
- Drug interactions
- Dosage information
- During pregnancy or Breastfeeding
- Reviews (2)
- Drug images
- Pricing & coupons
- En español
- Drug class: benzodiazepines
- Other brands
- Tranxene SD
Related treatment guides
1. "Product Information. Tranxene (clorazepate)." Abbott Pharmaceutical, Abbott Park, IL.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.