BuSpar Side Effects
Generic name: buspirone
Medically reviewed by Drugs.com. Last updated on May 22, 2023.
Note: This document contains side effect information about buspirone. Some dosage forms listed on this page may not apply to the brand name BuSpar.
Applies to buspirone: oral tablet.
Serious side effects of BuSpar
Along with its needed effects, buspirone (the active ingredient contained in BuSpar) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking buspirone:
- Chest pain
- fast or pounding heartbeat
- mental depression
- muscle weakness
- numbness, tingling, pain, or weakness in the hands or feet
- skin rash or hives
- sore throat
- stiffness of the arms or legs
- uncontrolled movements of the body
Get emergency help immediately if any of the following symptoms of overdose occur while taking buspirone:
Symptoms of overdose
- Dizziness or lightheadedness especially when getting up from a sitting or lying position suddenly
- drowsiness (severe)
- loss of consciousness
- nausea or vomiting
- stomach upset
- very small pupils of the eyes
Other side effects of BuSpar
Some side effects of buspirone may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
- Restlessness, nervousness, or unusual excitement
Less common or rare
- Blurred vision
- clamminess or sweating
- decreased concentration
- dryness of the mouth
- muscle pain, spasms, cramps, or stiffness
- ringing in the ears
- trouble with sleeping, nightmares, or vivid dreams
- unusual tiredness or weakness
For Healthcare Professionals
Applies to buspirone: compounding powder, oral tablet.
Very common (10% or more): Dizziness (12%), drowsiness (10%)
Common (1% to 10%): Lightheadedness, decreased concentration, numbness, paresthesia, incoordination, headache, tremor, syncope, seizures
Rare (less than 0.1%): Cerebrovascular accident
Very rare (less than 0.01%): Serotonin syndrome, amnesia, cogwheel rigidity, dystonia/dystonic reactions, dyskinesias (acute and tardive), ataxias, parkinsonism, akathisia, restless leg syndrome
Postmarketing reports: Vertigo, extrapyramidal symptoms, transient difficulty with recall[Ref]
Uncommon (0.1% to 1%): Hypotension, hypertension
Common (1% to 10%): Rash, sweating/clamminess
Uncommon (0.1% to 1%): Pruritus, flushing, easy bruising, hair loss, dry skin, facial edema, blisters
Rare (less than 0.1%): Acne, thinning of nails, ecchymosis, urticaria[Ref]
Common (1% to 10%): Nausea, dry mouth, abdominal/gastric distress, diarrhea, constipation, vomiting
Uncommon (0.1% to 1%): Flatulence, anorexia, increased appetite, salivation, irritable colon, rectal bleeding
Rare (less than 0.1%): Burning of the tongue[Ref]
Common (1% to 10%): Musculoskeletal aches/pains
Uncommon (0.1% to 1%): Muscle cramps, muscle spasms, rigid/stiff muscles, arthralgias
Rare (less than 0.1%): Muscle weakness[Ref]
Common (1% to 10%): Blurred vision
Uncommon (0.1% to 1%): Eye redness and itching, conjunctivitis, eye pain, eye pressure, photophobia
Very rare (less than 0.01%): Visual changes (including tunnel vision)[Ref]
Common (1% to 10%): Fatigue, weakness, tinnitus, sore throat
Uncommon (0.1% to 1%): Altered taste, altered smell, inner ear abnormality, edema, fever, roaring sensation in the head, malaise
Rare (less than 0.1%): Alcohol abuse, loss of voice, hiccoughs[Ref]
Common (1% to 10%): Insomnia, nervousness, excitement, anger/hostility, confusion, depression, dream disturbances, attention disturbance, sleep disorder
Uncommon (0.1% to 1%): Depersonalization, dysphoria, noise intolerance, euphoria, akathisia, fearfulness, loss of interest, dissociative reaction, hallucinations, involuntary movements, slowed reaction time, suicidal ideation, decreased or increased libido
Rare (less than 0.1%): Claustrophobia, cold intolerance, stupor, slurred speech, psychosis, delayed ejaculation, impotence
Very rare (less than 0.01%): Depersonalization
Postmarketing reports: Emotional lability, restlessness[Ref]
Common (1% to 10%): Nasal congestion, pharyngolaryngeal pain
Uncommon (0.1% to 1%): Hyperventilation, shortness of breath, chest congestion
Rare (less than 0.1%): Epistaxis[Ref]
Uncommon (0.1% to 1%): Urinary frequency, urinary hesitancy, menstrual irregularity and spotting, dysuria
Very rare (less than 0.01%): Urinary retention[Ref]
Uncommon (0.1% to 1%): Increases in hepatic aminotransferases (SGOT, SGPT)[Ref]
Rare (less than 0.1%): Galactorrhea, thyroid abnormality[Ref]
More about BuSpar (buspirone)
- Check interactions
- Compare alternatives
- Reviews (624)
- Drug images
- Dosage information
- Patient tips
- During pregnancy
- Support group
- Drug class: miscellaneous anxiolytics, sedatives and hypnotics
Related treatment guides
1. Product Information. Buspar (buspirone). Bristol-Myers Squibb. 2002.
2. Cerner Multum, Inc. UK Summary of Product Characteristics.
3. Cerner Multum, Inc. Australian Product Information.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.