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Oxazepam Side Effects

For the Consumer

Applies to oxazepam: oral capsule, oral tablet

Along with its needed effects, oxazepam may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking oxazepam:

Rare
  • Abdominal or stomach pain
  • black, tarry stools
  • chest pain
  • chills
  • clay-colored stools
  • cough
  • dark urine
  • dizziness
  • fainting
  • fever with or without chills
  • headache
  • itching or rash
  • light-colored stools
  • loss of appetite
  • nausea and vomiting
  • painful or difficult urination
  • shakiness and unsteady walk
  • shakiness in the legs, arms, hands, or feet
  • slurred speech
  • sore throat
  • sores, ulcers, or white spots on the lips or in the mouth
  • swelling
  • swollen glands
  • trouble breathing
  • unpleasant breath odor
  • unsteadiness, trembling, or other problems with muscle control or coordination
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • vomiting of blood
  • yellow eyes or skin
Incidence not known
  • Being forgetful
  • confusion about identity, place, and time
  • cough or hoarseness
  • decreased awareness or responsiveness
  • false or unusual sense of well-being
  • general feeling of tiredness or weakness
  • hallucinations
  • loss of bladder control
  • loss of memory
  • lower back or side pain
  • nightmares
  • pale skin
  • problems with memory
  • severe sleepiness
  • trouble sleeping
  • unusual excitement, nervousness, restlessness, or irritability

Get emergency help immediately if any of the following symptoms of overdose occur while taking oxazepam:

Symptoms of overdose
  • Blurred vision
  • change in consciousness
  • confusion
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • drowsiness
  • loss of consciousness
  • loss of strength or energy
  • muscle pain or weakness
  • sweating
  • unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
  • unusual weak feeling

Some side effects of oxazepam may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Rare
  • Decreased interest in sexual intercourse
  • feeling of constant movement of self or surroundings
  • inability to have or keep an erection
  • increased in sexual ability, desire, drive, or performance
  • increased interest in sexual intercourse
  • loss in sexual ability, desire, drive, or performance
  • rash with flat lesions or small raised lesions on the skin
  • sensation of spinning
Incidence not known
  • Double vision
  • menstrual changes
  • seeing double

For Healthcare Professionals

Applies to oxazepam: oral capsule, oral tablet

Nervous system

Rare (less than 0.1%): Slurred speech, tremor, ataxia
Frequency not reported: Drowsiness, amnesia, anterograde amnesia, reduced alertness, dizziness, light-headedness, vertigo, headache, syncope, dysarthria, changes in EEG pattern, stupor, memory impairment[Ref]

Other

Rare (less than 0.1%): Edema
Frequency not reported: Fever, fatigue[Ref]

Genitourinary

Rare (less than 0.1%): Altered libido
Frequency not reported: Incontinence, urinary retention, menstrual irregularities[Ref]

Hepatic

Rare (less than 0.1%): Jaundice, hepatic impairment
Frequency not reported: Increased liver enzymes[Ref]

Hematologic

Rare (less than 0.1%): Leukopenia
Frequency not reported: Blood dyscrasias (including agranulocytosis)[Ref]

Hypersensitivity

Frequency not reported: Hypersensitivity[Ref]

Cardiovascular

Frequency not reported: Hypotension[Ref]

Dermatologic

Rare (less than 0.1%): Minor diffuse skin rashes (morbilliform, urticarial and maculopapular)[Ref]

Gastrointestinal

Rare (less than 0.1%):Nausea
Frequency not reported: Salivation changes, gastrointestinal disorders[Ref]

General

The most commonly reported side effects were drowsiness, headache, and fatigue.[Ref]

Musculoskeletal

Frequency not reported: Muscle weakness[Ref]

Ocular

Frequency not reported: Blurred vision, diplopia[Ref]

Psychiatric

Rare (less than 0.1%): Lethargy
Frequency not reported: Disorientation, nightmares, mild excitatory effects with stimulation of affect, numbed emotions, restlessness, agitation, irritability, delusions, rages, psychoses, inappropriate behavior, behavioral adverse effects (including paradoxical aggressive outbursts), excitement, hallucinations, uncovering of depression with suicidal tendencies, withdrawal symptoms (including persistent tinnitus, involuntary movements, paresthesia, perceptual changes, confusion, convulsions, muscle cramps, abdominal cramps, vomiting), aggression, euphoria[Ref]

References

1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

2. Cerner Multum, Inc. "Australian Product Information." O 0

3. "Product Information. Serax (oxazepam)." Wyeth-Ayerst Laboratories, Philadelphia, PA.

Some side effects of oxazepam may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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