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User Reviews for Duloxetine to treat Anxiety

Also known as: Cymbalta, Irenka

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

Duloxetine Rating Summary

User Ratings
10
   
24%(64)
9
   
25%(66)
8
   
15%(39)
7
   
3%(6)
6
   
4%(10)
5
   
4%(10)
4
   
5%(11)
3
   
3%(8)
2
   
4%(9)
1
   
18%(47)
6.8/10 Average Rating
270 Ratings with 246 User Reviews

What next? Compare all 160 medications used in the treatment of Anxiety.

Reviews for Duloxetine

Cymbalta (duloxetine): "This medication really did work, and helped me with my anxiety, it increased my appetite, I was talkative, but... It turned me into a complete douche bag, I would scream at people and completely lose it after something insignificant happened, I was in a dark place and always on the edge."

   
4.0

Ken (taken for less than 1 month) June 21, 2019

3 users found this comment helpful.
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"I'm 20 and her anxiety since I was a kid. I developed agoraphobia, IBS and a panic disorder due to my anxiety and was in a really bad place. I'm 5 weeks in taking duloxetine and started leaving the house again and going back to education. I had side effects for the first 2 days but they were only mild. I feel great! I've tried so many other antidepressants and this is definitely the most effective!! 10/10"

   
10

Daisyyyy (taken for 1 to 6 months) June 20, 2019

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Cymbalta (duloxetine): "NOTHING is worth the suffering you will endure trying to come off this medication. Do not take this drug unless it is your last resort."

   
1.0

chloejo (taken for 1 to 6 months) June 10, 2019

8 users found this comment helpful.
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Cymbalta (duloxetine): "Cymbalta did not help me. I was on it for about 6 months and it literally did nothing. It worked for my mom, but not for me. I have tried it twice in my life and neither time did it help."

   
2.0

Khaleesi (taken for 6 months to 1 year) June 10, 2019

2 users found this comment helpful.
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Cymbalta (duloxetine): "Remember this, everyone is different. Find the right medicine for you. I went on Cymbalta 7 years ago after I had an autoimmune disease and suffered from depression & anxiety. It was great. I went off of it for 3.5 years. Now, married with two kids, my life was what I wanted, yet I was miserable--so much anxiety, mood swings, snapping at my husband and kids, no interest in fun activities. I couldn't stand myself. I decided to give Cymbalta a try again (generic version). Initial side effects lasted a week. SO tired, brain fog, no appetite, headache. By day 7, all gone. I can't believe how fast it's working for me. My anxiety is gone. I am calm and easy going. I feel like the best version of myself. I'm laughing with my kids and husband and don't overreact. I actually am looking forward to doing activities and I have been enjoying them. I have been more productive at work and oddly more organized. I've tried other medicine and it's shut me down like a zombie."

   
10

JDMAM June 10, 2019

15 users found this comment helpful.
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Cymbalta (duloxetine): "I was diagnosed with major depression at quite a young age. I started off with Prozac, which didn’t work for me, then Lexapro which made my skin crawl, then onto Viibryd, which I only took for a month because it was so expensive. Now I am on Cymbalta (day 2). I work as a CNA at a retirement home 6pm-6am. The doctor told me to take it on “my mornings” which is about 4 pm. My first night was awful. My blood pressure was 189/110 and heart rate was 172. I felt like my head was swimming and I was getting tongue tied even on simple words. I felt weak and hot and had diarrhea. I am also a smoker so I imagine that could’ve played a role with my elevated heart rate. But this is some strong stuff. I’m going to stick it out at least long enough to finish the bottle, and see if some of these side effects subside. High hopes!"

   
5.0

Sam (taken for less than 1 month) May 31, 2019

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"I was suffering from extreme anxiety, brought on by a bad reaction to an antibiotic. It lasted a year until I started taking duloxetine. Things improved almost immediately. I had some insomnia for a few days. Things continued to improve. Now, after two months my anxiety is gone, and I feel like my old self again. I have no side effects I am aware of, and am sleeping very well. I was afraid to take it due to many negative reviews. I am sure these bad reviews are valid, as every individual reacts differently. My advice would be to try it, but be very careful. If it seems to work great, if not consult with your doctor and if advised stop. My experience has been great, others have been terrible, so step carefully. It is giving me my life back."

   
10

John (taken for 1 to 6 months) May 21, 2019

6 users found this comment helpful.
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Cymbalta (duloxetine): "I got bad /severe serotonin syndrome from cymbalta 60 and tramadol 50. Everyone thought this was strange as both are low doses . Recently tried cymbalta a few months ago as mono therapy , after a month I got mild seritonin syndrome , confirmed by my psychiatrist , I had delerium, nausea, delusions , sweating and diarrhea , could this both times be from my huge caffeine in take I’ve had for years , as caffeine and cymbalta are both cyp1a2 substrates ? My son had severe reactions to multiple 2d6 substrates and gene testing confirmed he is a normal metaboliser. Was just too much meds hurting his 2d6 enzyme . Thoughts on my caffeine abuse with my cymbalta nasty reactions ? ?????"

   
1.0

Lee May 11, 2019

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Cymbalta (duloxetine): "After being diagnosed with depression as a result of chronic neck pain, my doctor prescribed 30mg of Cymbalta. The Cymbalta helped with the depression, but it also erased my ability to feel... anything. As I turned into an emotional zombie, my wife grew tired of being with an emotionless spouse and threatened to leave, with our children. Through pure luck and a misunderstanding, my wife called the police, believing I was preparing to take my own life. The police took me to a hospital for evaluation. During the interview, the doctor learned about my use of Cymbalta and took me off it, immediately. I got my emotions back AND my family back. I will never touch the stuff, again."

   
1.0

Chronically Pained (taken for 2 to 5 years) April 21, 2019

11 users found this comment helpful.
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Cymbalta (duloxetine): "I started on 30 mgs a day and stopped on the 5th day. I felt so nauseous and intestinally challenged. The drug also caused my heart to go into afib / aflutter with moderate tachycardia. As soon as I told the Doctor what was happening he had me stop immediately. Now I am waiting to see a cardiologist to assess the arrhythmia situation. I know the literature says that my side affects are rare, but it happened to me."

   
1.0

Bryan (taken for less than 1 month) April 9, 2019

14 users found this comment helpful.
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Cymbalta (duloxetine): "Cymbalta saved my life, I went from a severe agoraphobic with stomach pain, heart palpitations, hyperventilation and insane blood pressure issues on a daily basis to my fully functional self again. I was extremely dissociative before taking this drug and never left my bed because my panic disorder was so debilitating. After about a week on cymbalta, I was up and moving around in the world. Several months later, I'm now in college with a new job and excelling. I've had 2 panic attacks in the last 6 months. My only complaint is that it makes me very tired, but this is easily remedied by taking it in the evening instead of the morning."

   
9.0

Georgia (taken for 6 months to 1 year) March 25, 2019

20 users found this comment helpful.
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"I take 20mg of duloxetine because I’m super sensitive to any SSRI or SNRI, everybody’s different I felt quite nauseous and dizzy for the first 2/3 days and now it’s been 2 weeks now and I feel like my old self. I suffer with PTSD and I used to have crippling panic attacks where I got to I couldn't leave the house at all. Now I can get on a bus and do my normal things, still with anxiety but I am a lot better than I was and hopefully one day I won’t need this med to aid me. This is the first med I’ve kept taken as well with minimal side effects."

   
9.0

H March 24, 2019

5 users found this comment helpful.
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Cymbalta (duloxetine): "Cymbalta worked to saved my life after perimenopause made my already existent depression increase tenfold. My depression was so dark I felt like I was being held down in a dark abyss. If I didn't seek medical help, I honestly believe I would have taken my own life. 60mg of Cymbalta daily and I could get out of bed, live my life, and function as a loving single parent who could provide for her family. Now, ten years later I will discuss the increasing anxiety I am feeling. Will my Cymbalta dosage increase. I don't know. But I do know for those 10 years I was not just surviving I was living. Thanks to Cymbalta"

   
10

Missy (taken for 10 years or more) March 17, 2019

35 users found this comment helpful.
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Cymbalta (duloxetine): "I have tried cymbalta on 2 different occasions with worsening conditions. It is like all the other SSRI drugs. This medication caused me to become stiff and rigid. I have suffered from racing thoughts most of my life. My doctor finally put me back on benzodiazepines and I am like a new person. Myself again."

   
2.0

Jax103 (taken for 1 to 6 months) February 23, 2019

10 users found this comment helpful.
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Cymbalta (duloxetine): "I have been doing 30mg of cymbalta for the past four years and it was working so we'll.. recently I have had increased stress which is not helping my anxiety. I am starting 60g dosage tonight. I think my body has just gotten tolerant of the 30mg and I need in increase."

   
8.0

Muffin (taken for 2 to 5 years) February 14, 2019

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Cymbalta (duloxetine): "I've had GAD pretty much all my life but developed increasing depression and withdrawal from social activities. Finally I bit the bullet and told my doctor. He started me on duloxetine, 30 mg with the warnings about weight gain and sexual dysfunction and commented we could increase to 60 mg in three or four weeks if needed. Never needed the increase - 30mg is perfect. I have gained 4 or 5 pounds. I did notice the sexual dysfunction (loss of interest and difficulty "finishing" at first so I would hold my meds a day or two before bath and treat night which worked fine. Pretty much back to normal in that regard. The best thing is I can get more than one or two errands completed now. I call my pills "do lots of things" now!"

   
9.0

Pursuit (taken for 6 months to 1 year) February 11, 2019

16 users found this comment helpful.
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"I took my first dose last night and I woke up freaking out in a panic attack, dizzy, ears ringing, dry mouth, nausea, diarrhea. It was terrible! I will not be continuing this medication."

   
1.0

Hello123 (taken for less than 1 month) January 16, 2019

6 users found this comment helpful.
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"Duloxetine/cymbalta- I used this for about 8 years. It was to help me with my anxiety, depression and racing thoughts- I have to say, it worked amazing, but if I missed even a day I could feel the effects. It helped me so much that I eventually wanted to get off of it. I weaned myself off of this slowly. And had a great outcome. I've read so many posts about how awful getting off this drug can be so I was super scared to even attempt it.. but I knew I didn’t want to depend on it forever. I never got sick or had horrible withdrawals. I want everyone to know that even though some people had a bad experience with it, Not all of us did! It worked great for me while I needed it and when I was done and didn’t want it anymore I got off it just fine!"

   
9.0

MoniP January 12, 2019

16 users found this comment helpful.
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Cymbalta (duloxetine): "Don’t let the negative comments on here scare you. The truth is, Cymbalta works beautifully for some people and some people hate it. But that’s true with ANY antidepressant! Cymbalta saved me from extreme, constant anxiety and panic attacks. But I have tried other drugs-Zoloft, Lexapro, Paxil, Prozac,etc. Figured out I cannot take ANY SSRI. They cause my anxiety to go through the roof! Cymbalta is a SNRI. Works differently. I could not only tolerate it- it saved me. So, no- the medication shouldn’t be banned. It works wonders for some of us. If it didn’t work for you, accept it and try something else. But don’t scare other people away from trying something that could change their life in a positive way. They affect everyone differently, they all have side effects that differ for everyone and they are all difficult to quit taking."

   
10

Boomer (taken for 5 to 10 years) January 6, 2019

111 users found this comment helpful.
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"I have taken the drug Duloxetine for about 12 days. I do feel much better as far as the depression and anxiety. However, I am having bouts of diarrhea from about day 4 to the present. I do take other drugs which may cause the discomfort. The best part is that I don't have an overwhelming desire to eat. So I believe I have lost some weight with Duloxetine. Some other good news with the Duloxetine is that I am sleeping better and feeling much calmer. I hope this drug will work for me."

   
6.0

anitathom57 (taken for less than 1 month) January 2, 2019

9 users found this comment helpful.
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Cymbalta (duloxetine): "I've be on this medication for almost 12mths now (60mg) previously being on lexapro. I have had weight gain, but really can't blame this all on the meds. My symptoms of anxiety depression and OCD are very much under control and I didn't experience any serious side effects, only the occasional dizziness and some fatigue. I found duloxetine more effective than lexapro for me."

   
9.0

7rudy (taken for 6 months to 1 year) January 2, 2019

24 users found this comment helpful.
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Cymbalta (duloxetine): "One 30 MG dose caused me to have a panic attack. I reported the side effects to my doctor. Discontinued use. Scary, horrible feeling."

   
1.0

PL (taken for less than 1 month) December 29, 2018

13 users found this comment helpful.
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"Was only on this for a short time. The initial side effects were the worst. Extreme nausea, random bursts of anxiety (more unpredictable than usual), random suicidal thoughts, and very dopey and out of it. Later after the initial side effects faded I was more focused and interested in caring for myself so that was good, but I was far more prone to manic episodes from my depression (especially when socializing), and also saw an increase of symptoms of my Autism. After an average fight with my dad I had an extreme reaction to the stress (far worse than it should have been) including numbness of extremeties, hyperventilating, and a lot of panic. Called my doctor that night and told her I needed to wean off immediately as if I hadn't taken a Ativan I don't know what would have happened."

   
1.0

FrenchToastBabey (taken for 1 to 6 months) December 23, 2018

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"One word... WITHDRAWAL!! This has been said elsewhere, but having taken Duloxetine for only 3 months (to find it was still giving me very bad runs, headaches, brain fog etc) I took 10 weeks to come off. As soon as I hit zero all hell broke loose. Anxiety like I never knew existed, seizures (and 4 trips to the ER), along with period of suicidal depression and the usual (nausea, fog etc). I have been off them for 3 weeks and still not better. Any surprise that hundreds of people got a payout for what wasn't known about the side effects? Eli Lilly - you are complete and utter .."

   
1.0

Marcel (taken for 1 to 6 months) November 29, 2018

7 users found this comment helpful.
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Cymbalta (duloxetine): "I had a large but benign brain tumor removed a year and a half ago. After my recovery, I had depression and anxiety which I had never really had before. After dealing with it over a year, I started generic Cymbalta 3 months ago. First 2 months 30 mg a day. Some initial insomnia, 1 day of upset stomach, loss of appetite (lost 8 lbs) for about 3 weeks. Helped immediately with depression, anxiety issues took about 5 weeks. After 2 months, Dr put me on 60 mg a day which I've taken for 4 weeks now. Anxiety is so much better, feel it coming on now and then but it doesn't last. I've put the weight back on but nothing extra. Sleeping 6-7 hours a night, about average for me. This drug overall has really helped me, I take nothing else with it. I'm sorry to hear it effects some people so negatively, but please try to stay on this until your body can get used to the side effects. This drug has greatly improved my life."

   
9.0

g0ldon November 16, 2018

42 users found this comment helpful.
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