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User Reviews for Duloxetine

Also known as: Cymbalta, Irenka

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

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Duloxetine Rating Summary

User Ratings
10
   
25%(56)
9
   
25%(58)
8
   
16%(37)
7
   
3%(6)
6
   
4%(7)
5
   
4%(8)
4
   
5%(10)
3
   
4%(7)
2
   
4%(7)
1
   
16%(37)
6.9/10 Average Rating
233 Ratings with 209 User Reviews

What next? Compare all 177 medications used in the treatment of Anxiety.

Reviews for Duloxetine to treat Anxiety

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Cymbalta (duloxetine): "This medication honestly changed my life. I thought I was fine while taking it, so I went off cold turkey. It was the worst experience of my life. I took my 2 pills after about 9 days off. After an estimated 3 hours, I felt like my normal, happy, non-anxiety self again. I don't recommend it to anyone though. I tried about 4 different medications before Cymbalta was the one that helped me. Good luck!"

   
10

Anonymous (taken for 2 to 5 years) August 13, 2018

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Cymbalta (duloxetine): "About 8 years ago I was going through a major depression and anxiety and bipolar and OCD all wrapped in one. The psychiatrists I had been seeing tried using the old school drugs Zoloft etc. Nothing was helping so I checked myself into an inpatient program. Then the miracle happened. The in house Psychiatrist put me on CYMBALTA. He explained that it differed from the older medicines in that it affects two parts of the brain. I experienced very little side effects and within a couple weeks I was feeling like my old self. It truly is a miracle med in my opinion."

   
10

Comeback Kid (taken for 5 to 10 years) August 6, 2018

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Cymbalta (duloxetine): "I had several side effects including nausea, fatigue, sweating, nightmares, elevated blood pressure, and constipation."

   
1.0

Brie (taken for 2 to 5 years) August 2, 2018

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"Only on for 4 days but had severe insomnia."

   
1.0

Flossy (taken for less than 1 month) July 24, 2018

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Cymbalta (duloxetine): "Dealing with severe anxiety and OCD my whole life, I decided to try medication when I turned 20. While my first few days on Cymbalta (10mg) were torturous, probably party due to mental reservations about taking a pill every day (I experienced vomiting, headaches, dizzy spells, nausea, inability to sleep, and complete loss of appetite), I'm SO glad I stuck with the drug. Now I am on 80mg, and without sounding completely corny, I feel like I'm finally the person I'm meant to be. Since starting the pill I've started rock climbing, learned to drive, and just become a much happier, friendlier, and more confident person. My friends and family have all noticed a huge shift in my personality and I'm so thrilled I went on cymbalta."

   
10

LJ (taken for 6 months to 1 year) July 16, 2018

7 users found this comment helpful.
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Cymbalta (duloxetine): "I've had 2 occasions on anidepressants. 2010 on cymbalta 60mg for GAD. Weaned off after a year. Last Friday bad anxiety after drinking. Dr gave me .25mg xanax 3x a day & 30mg Duloxetine 1x a day. Dr said I could start with 60 but I felt that was to high to start. I've only taken 1 dose of the xanax Friday. On Sat the 30mg Duloxetine. Xanax helped 4-5 hr & tapered off I'm told quicker cuz I smoke cigs. Sat feeling anxiety in waves so took 30mg Duloxetine @ 2:30 PM. I had a slight dry mouth & some slight dizziness by 8:30 PM. But I actually feel pretty good. At tolerable anxiety level. Is it possible that 1 dose of Cymbalta actually made my anxiety start to dissipate already? Or maybe my body just eventually kicks out the anxiety like it has in the past & I don't need meds. Did I jump the gun taking that 1 dose of Duloxetine? I wish I knew because I don't know what to do now with the meds. I really hate taking them if I don't really need them"

   
5.0

Loupags July 15, 2018

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Cymbalta (duloxetine): "I've taken duloxetine for a few weeks. Sometimes I have feelings, like my head is light, as if I had no thoughts there. Then sometimes I have a million thoughts which scares me...has someone similar feelings? I take low dose, only 15mg."

zuzana (taken for less than 1 month) June 24, 2018

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Cymbalta (duloxetine): "I take Cymbalta 10 days. First week was good, bud today I feel worse. I had something like panic attack...has someone the same experience? Will it get better?"

Bobulocka (taken for less than 1 month) May 29, 2018

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"Started duloxetine for anxiety and panic attacks. Never helped with my off balance feeling, perhaps helped with panic somewhat. Started to slowly lower it after months of it and realizing it wasn't helping. I wouldn't recommend ever starting this medication simply because of the withdrawal. I didn't think it would be that bad. The floor moves under my feet, the floor drops out from under me, my heart gets electrocuted and sinks into the floor, my chest gets electrocuted and goes up into my head. My brain moves around. I get so dizzy I can barely walk. The anticipation of all of this when I walk causes extreme anxiety and panic. Would not recommend a drug with norepinephrine if you do not have depression. Try a SSRI."

   
1.0

Anonymous (taken for 1 to 6 months) May 19, 2018

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Cymbalta (duloxetine): "This drug was absolutely amazing when it worked for me. I started to notice resolution of my severe anxiety symptoms within a week with little to no side effects. Before I used this medication I was living in a constant state of anxiety where I would feel off balance most of the day and constantly fear that I was about to pass out. My chest would be tight most of the day and I would get sharp, shooting pains all over my chest area and I would feel like every day I was going to die and even more so when I would try to go to bed at night; I was certain that I wasn't going to wake up the next day. Also, I would feel like everything around me was sped up and I would get shortness of breath frequently through out the day as well as panic attacks and somehow I managed to function for two years in this living nightmare before I went and got help for myself."

   
10

mark May 13, 2018

12 users found this comment helpful.
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"This medication has been life changing for me. No side effects to mention apart from a bit of a tremor. Have been taking it about 3 to 4 weeks now. It cured my insomnia from day 1 and after a week or so I noticed a massive reduction in anxiety. Fingers crossed that continues. As an added bonus it really helped with pain from fibromyalgia and arthritis enabling me to cut dosage of my pain medication"

   
10

Jo (taken for less than 1 month) May 2, 2018

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Cymbalta (duloxetine): "Three to four years ago my terrific wife thought my behavior was changing (mostly impatient) while I was taking EFFEXOR so my Dr had me try Cybalta & my mood improved according to my wife. I also have mild-moderate depression and this drug also took care of that as well as my anxiety (occasional panic attacks--really scary). Now none!! Now the not-so-good-news. I believe the drug is attributable to increased ED, lower libido, tiredness, occasional brain 'zaps' (1-2 times/month on average usually at night when I first try to go to sleep, they last a few seconds but frightening nevertheless), Overall I recommend but realizing some of these situations could occur."

   
8.0

jimmyg (taken for 2 to 5 years) April 29, 2018

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Cymbalta (duloxetine): "Since my retirement life has taken a few major turns. Deaths in the family, reduced income, children with problems, greater interaction with my bipolar wife and aging finally brought me to a point of high anxiety. Ativan too much so doc started 20mg cymbalta. Still at 20mg, and any side effects were too mild to identify. I started calling it my "don't give a poop medicine" because I found I could deal with my wife's constant 'need' by just not caring. Just finished my taxes and any thoughts I had of discontinuing soon were wiped. Reading through these comments, I have seen the cluster of minor side effects that I was not associating with cymbalta. Afternoon fatigue, spaciness, headache that responds to water, unusual constipation and dream/wake state coupled with extended drowsiness after a normal nights sleep can be attributed to cymbalta. I was beginning to get anxious. Thank you all for sharing your experiences. I assure you that at least one person has benefitted and is grateful."

   
9.0

PapaDan April 18, 2018

17 users found this comment helpful.
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Cymbalta (duloxetine): "After my first dose of the generic version of Cymbalta yesterday evening for major anxiety and minor depression. I was surprised to feel a difference within a few hours. My mood lifted and I had more energy. I still felt slightly anxious. Initial side effects: quite bad insomnia, slight jitteriness, slight diarrhea, very slight confusion at times and nausea for the first 12 hours after taking it. After 2 weeks, I now have zero side effects and have changed to taking it in the mornings. It is a miracle drug for my depression! The constant dark feeling of sadness has lifted completely. It has also helped my anxiety quite a lot, however I still have periods of anxiousness. I am definitely going to stay on this medication as it has drastically improved the quality of my life."

   
10

stillholdingon (taken for less than 1 month) April 9, 2018

13 users found this comment helpful.
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Cymbalta (duloxetine): "This medication helped me so much! I battled severe depression in high school due to chronic illness and about a year and a half later developed a severe anxiety disorder. I started off on other meds (i.e. Lexapro, Zoloft, etc.) with little help. I've been taking duloxetine now for ten years and it makes a world of difference for me! Every medication reacts VERY differently in each individual and its a process of trial and error, but I'm very thankful for this medication. Are there side effects? Sure, like with any medication. My worst ones are always being hot and dry mouth (comes and goes). I've found ways to deal with those though and it doesn't take away the fact that my anxiety is helped tremendously and my depression nearly disappeared. I will battle anxiety for my whole life, I'm sure, so please don't think any drug is a magic, cure-all pill! BUT I can conscientiously recognize an anxiety attack and use my coping skills, whereas before, I felt completely out of control."

   
9.0

Luvpaws1990 April 5, 2018

8 users found this comment helpful.
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"This is for Sciencebitch: I'm going thru the same problems with generic brands switching since I was doing FINE on Teva. Have u found a generic thats as good as Teva?"

   
4.0

Jennjak (taken for 1 to 2 years) March 19, 2018

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Cymbalta (duloxetine): "Horrific drug that should be banned, the withdrawal was insane, even for the short time I was on it, thankfully I met thousands of others in a FB support group now with almost 15000 members on how to get off this poison safely and properly, via opening capsules and bead counting ( yes it's that bad to get off of) and a extremely slow taper..."

   
1.0

Tony (taken for 1 to 6 months) March 4, 2018

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Cymbalta (duloxetine): "I'm 46 and over all generally healthy. I have suffered with anxiety and PMDD for about 6 years. After trying many SSRI medications and taking a low dose of Xanax on a regular basis, Cymbalta has totally changed my life for the better. The mild side effects are far better than what I use to go through. I went from 20mg to 30mg and this works for me."

   
8.0

Lynn March 3, 2018

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Cymbalta (duloxetine): "My husband had Coronary artery bypass grafting (CABG) 2 years ago and 2 months after he developed severe anxiety. At first he was given Ativan to help him. He was then given Celexa and it sent him for a loop--SEVERE anxiety, so that didn't work. He decided he would just use Ativan during the day and Xanax to help him sleep. I finally convinced him that he needs a long term treatment. He is almost through his second week of Cymbalta. It is making him very tired, almost exhaustion and he feels like he is in a fog. He is still having his spells, but I don't think they are as severe. I keep encouraging him to give it more time. I hope this works, I want my outgoing, funny, and energetic husband back."

   
5.0

Grandma T (taken for less than 1 month) March 2, 2018

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Cymbalta (duloxetine): "I had substance abuse 7 years ago and suddenly developed anxiety disorder. I was put on many meds then on cymbalta 60mg and within 3 months everything was back to normal and my doc weaned me of another 3 months. I lived the best years of my life from 2012 traveling working got married have a daughter everything with 0 anxiety until last month. I started feeling like am losing my mind along with intense fear and then I realised my anxiety came back Same doc put me back on 30mg of cymbalta in the morning along with 2.5mg zyprexa at night for 1 month 10 days into the treatment felt normal again I couldn't be much happier went back to the old me BUT unfortunately the last 3 days anxiety came back very high. I talked to my doc today and he told me to keep the dosages like they are and to wait a little...so is it possible that the drug stopped working or its just my body is readjusting?? Did anyone have similar experience where the medication worked the first 10 days and then anxiety came back?"

   
7.0

Mcmo11 February 26, 2018

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Cymbalta (duloxetine): "I've been on Cymbalta for just less than a month. It has been a life saver for me. I have C-PTSD, brain trauma, anxiety, depression and borderline personality disorder. I've taken more meds than I can even remember. Cymbalta us working great and no side effects. I can go out in public now without anxiety attacks and I'm not sitting on the couch afraid to move. Good med for me. I take other meds also and was taken off of Klonopin. I know have more energy and happiness."

   
10

Anonymous January 8, 2018

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Cymbalta (duloxetine): "Cymbalta worked great for me and I'm blessed that it did. I had read many reviews of those unable to take it for various reasons and that scared me but my Dr. suggested I try it and I'm so glad I did. For 16 months I had zero anxiety and I went through hell for part of that time. Things were going so well I decided to get off of it because taking it had negatively impacted my BP. I went from 60mg to 30mg for 30 days and then started 20mg. During the time I was on 20mg I had my first anxiety attack in 16 months! I'm back on 60mg and hoping once a few weeks pass of being back on maintenance dose that the anxiety will go away again! Wish I had never tried to get off of it!"

   
9.0

Hoopita (taken for 1 to 2 years) January 8, 2018

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Cymbalta (duloxetine): "Didnt do much for OCD, Social Phobia, and other anxiety issues."

   
2.0

yearsofocd (taken for 1 to 6 months) January 7, 2018

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Cymbalta (duloxetine): "horrible made me so sick and weight gain of over 30kgs. caused nausea and migraines. Would give a 0 if I could almost ruined my life and made it almost impossible to work and enjoy life"

Aliceeee January 4, 2018

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Cymbalta (duloxetine): "Cymbalta was not a medication for me. Instead of helping me, it made me mean. I took it for a few days but that's all the time I needed to see the horrible side effects."

   
1.0

Clubqueen (taken for less than 1 month) December 26, 2017

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