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Meprobamate Dosage

Applies to the following strength(s): 400 mg ; 200 mg ; 600 mg

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Anxiety

1200 to 1600 mg orally divided in 3 or 4 doses
Maximum dose: 2400 mg per day

Comments:
-The lowest effective dose should be used in order to limit oversedation.
-The effectiveness beyond 4 months has not been assessed.

Uses: Management of anxiety disorders or for the short-term relief of anxiety symptoms.

Usual Pediatric Dose for Anxiety

Age: 6 to 12 years:
200 to 600 mg orally divided in 2 or 3 doses

Age: 13 years or older:
1200 to 1600 mg orally divided in 3 or 4 doses
Maximum dose: 2400 mg per day

Comments:
-The lowest effective dose should be used in order to limit oversedation.
-The effectiveness beyond 4 months has not been assessed.

Uses: Management of anxiety disorders or for the short-term relief of anxiety symptoms

Renal Dose Adjustments

Use with caution

Liver Dose Adjustments

Use with caution

Dose Adjustments

Elderly: Use with cation; dose selection should be cautious starting at the low end of the dosing range.

Abrupt discontinuation should be avoided; reduce dose gradually over a period of 1 to 2 weeks; alternatively, a long-acting barbiturate may be substituted, then gradually withdrawn.

Precautions

Safety and efficacy have not been established in patients younger than 6 years.

Consult WARNINGS section for additional precautions.

US Controlled Substance: Schedule IV

Dialysis

Data not available

Other Comments

Administration advice:
-Take orally 3 to 4 times a day

General:
-Careful supervision of dose and amounts prescribed is necessary since this drug is known to produce physical and psychological dependence.
-Abrupt discontinuation, especially after prolonged use, should be avoided; onset of withdrawal symptoms is usually within 12 to 48 hours and symptoms usually cease within the next 12 to 48 hours.
-Continued need should be regularly reassessed.

Monitoring:
-Monitor for over sedation
-Monitor for abuse

Patient advice:
-Patients should be advised that this drug may impair their ability to perform hazardous tasks including driving.
-Patients should be aware that this drug has been known to be abused producing physical and psychological dependence when used at higher than recommended doses; withdrawal reactions are possible and patients should discuss discontinuation with their healthcare provider.
-Patients should be informed that their tolerance for alcohol and other CNS depressants will be diminished; concurrent use is generally not recommended, but should be discussed with their healthcare provider.

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