Meprobamate Pregnancy and Breastfeeding Warnings
Medically reviewed by Drugs.com. Last updated on Jun 22, 2021.
Meprobamate is also known as: Equanil, MB-TAB, Miltown
Meprobamate Pregnancy Warnings
An increased risk of congenital malformations during the first trimester of pregnancy has been suggested. This drug passes the placental barrier and is present in the umbilical cord blood at or near maternal plasma levels.
Use should be avoided especially during the first trimester
Risk Summary: An increased risk of congenital malformations has been associated with minor tranquilizers including this drug.
Comments: Women of childbearing potential should be advised of risks.
Meprobamate Breastfeeding Warnings
Use is not recommended
Excreted into human milk: Yes
Comment: Monitor infant for sedation, especially if mother is concurrently taking other drugs that may cause sedation.
Breast milk concentrations of this drug have been found to be up to 4 times those in maternal plasma. While it may not be a reason to discontinue breastfeeding, other agents may be preferred due to limited information available with this drug.
See also
References for pregnancy information
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- "Product Information. Meprobamate (meprobamate)." Alembic Pharmaceuticals (2016):
References for breastfeeding information
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- United States National Library of Medicine "Toxnet. Toxicology Data Network. http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT" (2013):
- "Product Information. Meprobamate (meprobamate)." Alembic Pharmaceuticals (2016):
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.