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Meprobamate Pregnancy and Breastfeeding Warnings

Meprobamate is also known as: Equanil, MB-TAB, Miltown

Meprobamate Pregnancy Warnings

An increased risk of congenital malformations during the first trimester of pregnancy has been suggested. This drug passes the placental barrier and is present in the umbilical cord blood at or near maternal plasma levels.

Use should be avoided especially during the first trimester Risk Summary: An increased risk of congenital malformations has been associated with minor tranquilizers including this drug. Comments: Women of childbearing potential should be advised of risks.

See references

Meprobamate Breastfeeding Warnings

Use is not recommended Excreted into human milk: Yes Comment: Monitor infant for sedation, especially if mother is concurrently taking other drugs that may cause sedation.

Breast milk concentrations of this drug have been found to be up to 4 times those in maternal plasma. While it may not be a reason to discontinue breastfeeding, other agents may be preferred due to limited information available with this drug.

See references

References for pregnancy information

  1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  2. "Product Information. Meprobamate (meprobamate)." Alembic Pharmaceuticals, Bridgewater, NJ.

References for breastfeeding information

  1. United States National Library of Medicine "Toxnet. Toxicology Data Network. Available from: URL: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT." ([cited 2013 -]):
  2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  3. "Product Information. Meprobamate (meprobamate)." Alembic Pharmaceuticals, Bridgewater, NJ.

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