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Medications for Epilepsy

The medications listed below are related to or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
Keppra 5.5 107 reviews for Keppra to treat Epilepsy Rx C N X
Generic name:
levetiracetam systemic
Drug class:
pyrrolidine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
levetiracetam 5.6 162 reviews for levetiracetam to treat Epilepsy Rx C N X
Generic name:
levetiracetam systemic
Brand names:
Keppra, Keppra XR, Elepsia XR, Roweepra, Roweepra XR, Spritam
Drug class:
pyrrolidine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
lamotrigine 6.3 75 reviews for lamotrigine to treat Epilepsy Rx C N X
Generic name:
lamotrigine systemic
Brand names:
Lamictal, Lamictal XR, Lamictal CD, Lamictal ODT, Subvenite
Drug class:
triazine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
carbamazepine 6.5 77 reviews for carbamazepine to treat Epilepsy Rx D N X
Generic name:
carbamazepine systemic
Brand names:
Tegretol, Carbatrol, Tegretol XR, Epitol
Drug class:
dibenzazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
gabapentin 7.2 18 reviews for gabapentin to treat Epilepsy Rx C N X
Generic name:
gabapentin systemic
Brand name:
Neurontin
Drug class:
gamma-aminobutyric acid analogs
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Depakote 6.4 59 reviews for Depakote to treat Epilepsy Rx D N X
Generic name:
divalproex sodium systemic
Drug class:
fatty acid derivative anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Dilantin 7.7 30 reviews for Dilantin to treat Epilepsy Rx D N X
Generic name:
phenytoin systemic
Drug class:
hydantoin anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Tegretol 6.4 34 reviews for Tegretol to treat Epilepsy Rx D N X
Generic name:
carbamazepine systemic
Drug class:
dibenzazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Lamictal 5.5 19 reviews for Lamictal to treat Epilepsy Rx C N X
Generic name:
lamotrigine systemic
Drug class:
triazine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
divalproex sodium 6.5 86 reviews for divalproex sodium to treat Epilepsy Rx D N X
Generic name:
divalproex sodium systemic
Brand names:
Depakote, Depakote ER, Depakote Sprinkles
Drug class:
fatty acid derivative anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Neurontin 8.0 5 reviews for Neurontin to treat Epilepsy Rx C N X
Generic name:
gabapentin systemic
Drug class:
gamma-aminobutyric acid analogs
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
clonazepam 9.3 11 reviews for clonazepam to treat Epilepsy Rx D 4 X
Generic name:
clonazepam systemic
Brand name:
Klonopin
Drug class:
benzodiazepines, benzodiazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
phenytoin 7.6 37 reviews for phenytoin to treat Epilepsy Rx D N X
Generic name:
phenytoin systemic
Brand names:
Dilantin, Phenytoin Sodium, Phenytek
Drug class:
hydantoin anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
topiramate 5.0 9 reviews for topiramate to treat Epilepsy Rx D N X
Generic name:
topiramate systemic
Brand names:
Topamax, Trokendi XR, Eprontia, Qudexy XR
Drug class:
carbonic anhydrase inhibitor anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Depakote ER 6.7 21 reviews for Depakote ER to treat Epilepsy Rx D N X
Generic name:
divalproex sodium systemic
Drug class:
fatty acid derivative anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Carbatrol 7.8 8 reviews for Carbatrol to treat Epilepsy Rx D N X
Generic name:
carbamazepine systemic
Drug class:
dibenzazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
clobazam 6.6 27 reviews for clobazam to treat Epilepsy Rx C 4 X
Generic name:
clobazam systemic
Drug class:
benzodiazepines, benzodiazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Lyrica 6.1 9 reviews for Lyrica to treat Epilepsy Rx C 5 X
Generic name:
pregabalin systemic
Drug class:
gamma-aminobutyric acid analogs
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Vimpat 7.3 23 reviews for Vimpat to treat Epilepsy Rx C 5 X
Generic name:
lacosamide systemic
Drug class:
miscellaneous anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Keppra XR 7.0 8 reviews for Keppra XR to treat Epilepsy Rx C N X
Generic name:
levetiracetam systemic
Drug class:
pyrrolidine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Tegretol XR 7.4 11 reviews for Tegretol XR to treat Epilepsy Rx D N X
Generic name:
carbamazepine systemic
Drug class:
dibenzazepine anticonvulsants
For consumers:
dosage, interactions, side effects
oxcarbazepine 5.6 15 reviews for oxcarbazepine to treat Epilepsy Rx C N X
Generic name:
oxcarbazepine systemic
Brand names:
Trileptal, Oxtellar XR
Drug class:
dibenzazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
valproic acid 5.1 8 reviews for valproic acid to treat Epilepsy Rx D N X
Generic name:
valproic acid systemic
Brand name:
Valproate Sodium
Drug class:
fatty acid derivative anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Trileptal 7.5 8 reviews for Trileptal to treat Epilepsy Rx C N X
Generic name:
oxcarbazepine systemic
Drug class:
dibenzazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Topamax 4.5 4 reviews for Topamax to treat Epilepsy Rx D N X
Generic name:
topiramate systemic
Drug class:
carbonic anhydrase inhibitor anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
lacosamide 7.2 27 reviews for lacosamide to treat Epilepsy Rx C 5 X
Generic name:
lacosamide systemic
Brand names:
Vimpat, Motpoly XR
Drug class:
miscellaneous anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
pregabalin 6.1 10 reviews for pregabalin to treat Epilepsy Rx C 5 X
Generic name:
pregabalin systemic
Brand name:
Lyrica
Drug class:
gamma-aminobutyric acid analogs
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Briviact 6.2 42 reviews for Briviact to treat Epilepsy Rx C 5 X
Generic name:
brivaracetam systemic
Drug class:
pyrrolidine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Felbatol 7.8 6 reviews for Felbatol to treat Epilepsy Rx C N X
Generic name:
felbamate systemic
Drug class:
carbamate anticonvulsants
For consumers:
dosage, interactions, side effects
Fycompa 6.0 48 reviews for Fycompa to treat Epilepsy Rx C 3 X
Generic name:
perampanel systemic
Drug class:
AMPA receptor antagonists
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Epitol 5.3 4 reviews for Epitol to treat Epilepsy Rx D N X
Generic name:
carbamazepine systemic
Drug class:
dibenzazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Lamictal XR 10 1 review for Lamictal XR to treat Epilepsy Rx C N X
Generic name:
lamotrigine systemic
Drug class:
triazine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Klonopin 5.0 1 review for Klonopin to treat Epilepsy Rx D 4 X
Generic name:
clonazepam systemic
Drug class:
benzodiazepines, benzodiazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Phenytoin Sodium Rate Add review Rx D N X
Generic name:
phenytoin systemic
Drug class:
hydantoin anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
acetazolamide 9.5 2 reviews for acetazolamide to treat Epilepsy Rx C N
Generic name:
acetazolamide systemic
Drug class:
carbonic anhydrase inhibitors, carbonic anhydrase inhibitor anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Aptiom 7.0 14 reviews for Aptiom to treat Epilepsy Rx C N X
Generic name:
eslicarbazepine systemic
Drug class:
dibenzazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Depakote Sprinkles Rate Add review Rx D N X
Generic name:
divalproex sodium systemic
Drug class:
fatty acid derivative anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Cerebyx Rate Add review Rx D N X
Generic name:
fosphenytoin systemic
Drug class:
hydantoin anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
felbamate 7.6 11 reviews for felbamate to treat Epilepsy Rx C N X
Generic name:
felbamate systemic
Brand name:
Felbatol
Drug class:
carbamate anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Sabril Rate Add review Rx C N X
Generic name:
vigabatrin systemic
Drug class:
gamma-aminobutyric acid analogs
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Trokendi XR 7.0 3 reviews for Trokendi XR to treat Epilepsy Rx D N X
Generic name:
topiramate systemic
Drug class:
carbonic anhydrase inhibitor anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Valproate Sodium 5.0 2 reviews for Valproate Sodium to treat Epilepsy Rx D N X
Generic name:
valproic acid systemic
For consumers:
dosage, interactions, side effects
Lamictal CD Rate Add review Rx C N X
Generic name:
lamotrigine systemic
Drug class:
triazine anticonvulsants
For consumers:
dosage, interactions, side effects
Lamictal ODT Rate Add review Rx C N X
Generic name:
lamotrigine systemic
Drug class:
triazine anticonvulsants
For consumers:
dosage, interactions, side effects
lorazepam Rate Add review Rx D 4 X
Generic name:
lorazepam systemic
Drug class:
benzodiazepines, miscellaneous antiemetics, benzodiazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Oxtellar XR Rate Add review Rx C N X
Generic name:
oxcarbazepine systemic
Drug class:
dibenzazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
primidone 9.3 3 reviews for primidone to treat Epilepsy Rx N N X
Generic name:
primidone systemic
Brand name:
Mysoline
Drug class:
barbiturate anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Subvenite Rate Add review Rx C N X
Generic name:
lamotrigine systemic
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
zonisamide 10 1 review for zonisamide to treat Epilepsy Rx C N X
Generic name:
zonisamide systemic
Drug class:
carbonic anhydrase inhibitor anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
brivaracetam 6.4 47 reviews for brivaracetam to treat Epilepsy Rx C 5 X
Generic name:
brivaracetam systemic
Brand name:
Briviact
Drug class:
pyrrolidine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
diazepam Rate Add review Rx D 4 X
Generic name:
diazepam systemic
Drug class:
benzodiazepines, benzodiazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Elepsia XR Rate Add review Rx C N X
Generic name:
levetiracetam systemic
Drug class:
pyrrolidine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Eprontia Rate Add review Rx D N X
Generic name:
topiramate systemic
Drug class:
carbonic anhydrase inhibitor anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
perampanel 5.9 52 reviews for perampanel to treat Epilepsy Rx C 3 X
Generic name:
perampanel systemic
Brand name:
Fycompa
Drug class:
AMPA receptor antagonists
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
phenobarbital 10 2 reviews for phenobarbital to treat Epilepsy Rx D 4 X
Generic name:
phenobarbital systemic
Drug class:
barbiturates, barbiturate anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Phenytek 10 1 review for Phenytek to treat Epilepsy Rx D N X
Generic name:
phenytoin systemic
Drug class:
hydantoin anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Qudexy XR Rate Add review Rx D N X
Generic name:
topiramate systemic
Drug class:
carbonic anhydrase inhibitor anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Roweepra Rate Add review Rx C N X
Generic name:
levetiracetam systemic
Drug class:
pyrrolidine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Roweepra XR Rate Add review Rx C N X
Generic name:
levetiracetam systemic
Drug class:
pyrrolidine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Spritam 10 1 review for Spritam to treat Epilepsy Rx C N X
Generic name:
levetiracetam systemic
Drug class:
pyrrolidine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
vigabatrin 9.0 1 review for vigabatrin to treat Epilepsy Rx C N X
Generic name:
vigabatrin systemic
Brand names:
Sabril, Vigadrone, Vigpoder
Drug class:
gamma-aminobutyric acid analogs
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
eslicarbazepine 7.1 15 reviews for eslicarbazepine to treat Epilepsy Rx C N X
Generic name:
eslicarbazepine systemic
Brand name:
Aptiom
Drug class:
dibenzazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
ethosuximide Rate Add review Rx N N X
Generic name:
ethosuximide systemic
Drug class:
succinimide anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
fosphenytoin Rate Add review Rx D N X
Generic name:
fosphenytoin systemic
Brand name:
Cerebyx
Drug class:
hydantoin anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Gabitril 9.0 1 review for Gabitril to treat Epilepsy Rx C N X
Generic name:
tiagabine systemic
Drug class:
gamma-aminobutyric acid reuptake inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Motpoly XR Rate Add review Rx C 5 X
Generic name:
lacosamide systemic
Drug class:
miscellaneous anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Mysoline 9.0 2 reviews for Mysoline to treat Epilepsy Rx N N X
Generic name:
primidone systemic
Drug class:
barbiturate anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
tiagabine 9.0 1 review for tiagabine to treat Epilepsy Rx C N X
Generic name:
tiagabine systemic
Brand name:
Gabitril
Drug class:
gamma-aminobutyric acid reuptake inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Vigadrone Rate Add review Rx C N X
Generic name:
vigabatrin systemic
Drug class:
gamma-aminobutyric acid analogs
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
clorazepate Rate Add review Rx N 4 X
Generic name:
clorazepate systemic
Drug class:
benzodiazepines
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
rufinamide Rate Add review Rx C N X
Generic name:
rufinamide systemic
Drug class:
dibenzazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Vigpoder Rate Add review Rx C N X
Generic name:
vigabatrin systemic
Drug class:
gamma-aminobutyric acid analogs
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information

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Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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