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Nonsteroidal anti-inflammatory agents

Other names: NSAIDs

What are Nonsteroidal anti-inflammatory agents

Nonsteroidal anti-inflammatory agents (usually abbreviated to NSAIDs) are a group of medicines that have anti-inflammatory (reduce inflammation), analgesic (relieve pain) and antipyretic (lower temperature) effects.

Although different NSAIDs have different structures, they all work by blocking cyclo-oxygenase (COX) enzymes. There are two main types of COX enzymes: COX-1 and COX-2. Both types produce produce prostaglandins; however, the main function of COX-1 enzymes is to produce baseline levels of prostaglandins that activate platelets and protect the lining of the gastrointestinal tract, whereas COX-2 enzymes are responsible for releasing prostaglandins after infection or injury. Prostaglandins have a number of different effects, one of which is to regulate inflammation.

Most NSAIDs inhibit both enzymes, although a few are available that mainly inhibit COX-2. The pain-relieving and anti-inflammatory effects of NSAIDs are mainly due to inhibition of COX-2, and their unwanted side effects are largely due to inhibition of COX-1.

List of Nonsteroidal anti-inflammatory agents:

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Drug Name DownUp( View by: Brand | Generic ) Reviews Ratings DownUp
ketoprofen systemic (Pro, More...)
21 reviews
   
9.2
fenoprofen systemic (Pro, More...)
2 reviews
   
8.7
tolmetin systemic (Pro, More...)
2 reviews
   
8.5
sulindac systemic (Pro, More...)
17 reviews
   
8.1
indomethacin systemic (Pro, More...)
133 reviews
   
8.0
diclofenac / misoprostol systemic (Pro, More...)
41 reviews
   
7.9
piroxicam systemic (Pro, More...)
22 reviews
   
7.9
diclofenac systemic (Pro, More...)
357 reviews
   
7.7
esomeprazole / naproxen systemic (Pro, More...)
22 reviews
   
7.5
etodolac systemic (Pro, More...)
54 reviews
   
7.5
ibuprofen systemic (Pro, More...)
98 reviews
   
7.4
ketorolac systemic (Pro, More...)
215 reviews
   
7.3
flurbiprofen systemic (Pro, More...)
8 reviews
   
7.2
meloxicam systemic (Pro, More...)
298 reviews
   
7.0
naproxen systemic (Pro, More...)
383 reviews
   
7.0
nabumetone systemic (Pro, More...)
50 reviews
   
6.4
oxaprozin systemic (Pro, More...)
7 reviews
   
6.4
mefenamic acid systemic (Pro, More...)
37 reviews
   
6.3
famotidine / ibuprofen systemic (Pro, More...)
12 reviews
   
6.1
bromfenac systemic (More...)
0 reviews
   
0.0
lansoprazole / naproxen systemic (More...)
0 reviews
   
0.0
meclofenamate systemic (Pro, More...)
0 reviews
   
0.0
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