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Feldene

Generic Name: piroxicam (peer OX i kam)
Brand Name: Feldene

Medically reviewed by Drugs.com on Aug 13, 2019 – Written by Cerner Multum

What is Feldene?

Feldene is a nonsteroidal anti-inflammatory drug (NSAID).

Feldene is used to treat pain or inflammation caused by osteoarthritis or rheumatoid arthritis.

Feldene may also be used for purposes not listed in this medication guide.

Important Information

Feldene can increase your risk of fatal heart attack or stroke. Do not use Feldene just before or after heart bypass surgery (coronary artery bypass graft, or CABG). This medicine may also cause stomach or intestinal bleeding, which can be fatal.

Before taking this medicine

You should not use Feldene if you are allergic to it, or if you have ever had an asthma attack or severe allergic reaction after taking aspirin or an NSAID.

Feldene can increase your risk of fatal heart attack or stroke, even if you don't have any risk factors. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG).

Feldene may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using this medicine, especially in older adults.

Tell your doctor if you have ever had:

  • heart disease, high blood pressure, or if you smoke;

  • a heart attack, stroke, or blood clot;

  • a stomach ulcer or stomach bleeding (especially while using an NSAID);

  • asthma; or

  • liver or kidney disease.

Taking Feldene during the last 3 months of pregnancy may harm the unborn baby. Tell your doctor if you are pregnant.

Ovulation (release of an egg from your ovary) could be delayed while you are taking Feldene. This effect is usually not permanent. You should not take this medicine while you are trying to get pregnant.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

Feldene is not approved for use by anyone younger than 18 years old.

How should I take Feldene?

Follow all directions on your prescription label and read all medication guides. Your doctor may occasionally change your dose. Use the lowest dose that is effective in treating your condition.

It may take up to 2 weeks before your symptoms improve. Keep using the medicine as directed and tell your doctor if your symptoms do not improve.

If you use Feldene long-term, you may need frequent medical tests.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include nausea, vomiting, stomach pain, black or bloody stools, or coughing up blood.

What should I avoid while taking Feldene?

Avoid drinking alcohol. It may increase your risk of stomach bleeding.

Avoid taking aspirin while you are taking Feldene.

Ask a doctor or pharmacist before using other medicines for pain, fever, swelling, or cold/flu symptoms. They may contain ingredients similar to Feldene (such as aspirin, ibuprofen, ketoprofen, or naproxen).

Feldene side effects

Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Get emergency medical help if you have signs of a heart attack or stroke: chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, leg swelling, feeling short of breath.

Stop using Feldene and call your doctor at once if you have:

  • severe headache, blurred vision, pounding in your neck or ears;

  • heart problems--swelling, rapid weight gain, feeling short of breath;

  • liver problems--loss of appetite, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

  • signs of stomach bleeding--bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;

  • kidney problems--little or no urination, swelling in your feet or ankles, feeling tired or short of breath; or

  • low red blood cells (anemia)--pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet.

Common side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Feldene?

Ask your doctor before using Feldene if you take an antidepressant. Taking certain antidepressants with an NSAID may cause you to bruise or bleed easily.

Tell your doctor about all your other medicines, especially:

  • lithium;

  • methotrexate;

  • a blood thinner or other medication used to prevent blood clots;

  • heart or blood pressure medication, including a diuretic or "water pill"; or

  • steroid medicine (such as prednisone).

This list is not complete. Other drugs may affect Feldene, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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