Feldene Alternatives Compared
| Feldene | Methotrexate | Hydroxychloroquine |
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| Feldene (piroxicam) | Methotrexate | Hydroxychloroquine |
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Prescription only
Prescribed for Rheumatoid Arthritis, Pain, Osteoarthritis, Frozen Shoulder, Temporomandibular Joint Disorder. Feldene may also be used for purposes not listed in this medication guide. |
Prescription only
Methotrexate may be considered for the treatment of psoriasis or rheumatoid arthritis if other treatments have failed. It may also be used in certain cancers. Side effects can be severe and... View more |
Prescription only
Prescribed for Rheumatoid Arthritis, Lupus, Lichen Planopilaris, Lyme Disease - Arthritis, Dermatomyositis, Malaria, Malaria Prevention, Sjogren's Syndrome, Undifferentiated Connective Tissue... View more |
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| More about Feldene (piroxicam) | More about Methotrexate | More about Hydroxychloroquine | ||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||
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Feldene has an average rating of 7.9 out of 10 from a total of 13 ratings on Drugs.com. 55% of reviewers reported a positive effect, while 0% reported a negative effect. |
Methotrexate has an average rating of 6.6 out of 10 from a total of 334 ratings on Drugs.com. 54% of reviewers reported a positive effect, while 23% reported a negative effect. |
Hydroxychloroquine has an average rating of 6.5 out of 10 from a total of 354 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 27% reported a negative effect. |
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| Drug Class | ||||||||||||||||||
| Side Effects | ||||||||||||||||||
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See also: Feldene side effects in more detail. |
See also: methotrexate side effects in more detail. |
See also: hydroxychloroquine side effects in more detail. |
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| Generic Availability | ||||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all methotrexate prices |
View all hydroxychloroquine prices |
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| Dosage Forms Available | ||||||||||||||||||
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| Brand Names | ||||||||||||||||||
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N/A |
Jylamvo, Methotrexate LPF Sodium, Otrexup, Rasuvo, Trexall, Xatmep | Plaquenil, Sovuna | ||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||
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70.5 hours |
15 hours |
N/A |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category N
Not classified
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||
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A total of 388 drugs are known to interact with Feldene:
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A total of 695 drugs are known to interact with methotrexate:
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A total of 466 drugs are known to interact with hydroxychloroquine:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||
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| Disease Interactions | ||||||||||||||||||
| First Approval Date | ||||||||||||||||||
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April 06, 1982 |
December 07, 1953 |
N/A |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||
| Patient resources | ||||||||||||||||||
| Professional Resources | ||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.