Medications for GERD
Other names: Acid reflux; Esophageal Reflux; Gastroesophageal Reflux Disease; Heartburn; Pyrosis; Reflux
See also: sub-topics
Drugs used to treat GERD
The following list of medications are in some way related to or used in the treatment of this condition.
Drug name | Rating | Reviews | Activity ? | Rx/OTC | Pregnancy | CSA | Alcohol |
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omeprazole | 4.8 | 251 reviews | Rx/OTC | ||||
Generic name: omeprazole systemic Brand names: Prilosec, Prilosec OTC Drug class: proton pump inhibitors For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph, Prescribing Information |
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pantoprazole | 4.5 | 247 reviews | Rx | ||||
Generic name: pantoprazole systemic Brand names: Protonix, Protonix IV Drug class: proton pump inhibitors For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph, Prescribing Information |
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Nexium | 5.5 | 152 reviews | Rx | ||||
Generic name: esomeprazole systemic Drug class: proton pump inhibitors For consumers: dosage, interactions, side effects For professionals: Prescribing Information |
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Protonix | 6.5 | 50 reviews | Rx | ||||
Generic name: pantoprazole systemic Drug class: proton pump inhibitors For consumers: dosage, interactions, side effects For professionals: Prescribing Information |
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famotidine | 3.8 | 88 reviews | Rx/OTC | ||||
Generic name: famotidine systemic Brand names: Pepcid, Pepcid AC, Acid Controller Maximum Strength, Acid Controller Original Strength, Acid Reducer Maximum Strength, Heartburn Relief, Pepcid AC Chewable Tablets, Heartburn Relief Maximum Strength, Pepcid Oral Suspension …show all Drug class: H2 antagonists For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph, Prescribing Information |
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Prilosec | 6.7 | 37 reviews | Rx | ||||
Generic name: omeprazole systemic Drug class: proton pump inhibitors For consumers: dosage, interactions, side effects For professionals: Prescribing Information |
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Dexilant | 6.2 | 162 reviews | Rx | ||||
Generic name: dexlansoprazole systemic Drug class: proton pump inhibitors For consumers: dosage, interactions, side effects For professionals: Prescribing Information |
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Aciphex | 9.3 | 36 reviews | Rx | ||||
Generic name: rabeprazole systemic Drug class: proton pump inhibitors For consumers: dosage, interactions, side effects For professionals: Prescribing Information |
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Prilosec OTC | 8.5 | 14 reviews | OTC | ||||
Generic name: omeprazole systemic Drug class: proton pump inhibitors For consumers: dosage, interactions, side effects |
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lansoprazole | 6.6 | 93 reviews | Rx/OTC | ||||
Generic name: lansoprazole systemic Brand names: Prevacid, Prevacid SoluTab, Prevacid OTC Drug class: proton pump inhibitors For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph, Prescribing Information |
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Prevacid | 7.8 | 44 reviews | Rx | ||||
Generic name: lansoprazole systemic Drug class: proton pump inhibitors For consumers: dosage, interactions, side effects For professionals: Prescribing Information |
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esomeprazole | 5.5 | 184 reviews | Rx/OTC | ||||
Generic name: esomeprazole systemic Brand names: Nexium, Nexium 24HR, Nexium IV Drug class: proton pump inhibitors For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph, Prescribing Information |
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Pepcid | 6.8 | 4 reviews | Rx | ||||
Generic name: famotidine systemic Drug class: H2 antagonists For consumers: dosage, interactions, side effects For professionals: Prescribing Information |
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rabeprazole | 8.1 | 52 reviews | Rx | ||||
Generic name: rabeprazole systemic Brand names: Aciphex, Aciphex Sprinkle Drug class: proton pump inhibitors For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph, Prescribing Information |
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sucralfate | 6.4 | 84 reviews | Rx | ||||
Generic name: sucralfate systemic Brand name: Carafate Drug class: miscellaneous GI agents For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph, Prescribing Information |
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Pepcid AC | Rate | Add review | OTC | ||||
Generic name: famotidine systemic Drug class: H2 antagonists For consumers: dosage, interactions, side effects |
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Carafate | 6.4 | 23 reviews | Rx | ||||
Generic name: sucralfate systemic Drug class: miscellaneous GI agents For consumers: dosage, interactions, side effects For professionals: Prescribing Information |
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Nexium 24HR | 9.7 | 4 reviews | OTC | ||||
Generic name: esomeprazole systemic Drug class: proton pump inhibitors For consumers: dosage, interactions, side effects |
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Protonix IV | 9.0 | 1 review | Rx | ||||
Generic name: pantoprazole systemic Drug class: proton pump inhibitors For consumers: dosage, interactions, side effects |
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Acid Controller Maximum Strength | Rate | Add review | OTC | ||||
Generic name: famotidine systemic Drug class: H2 antagonists For consumers: dosage, interactions, side effects For professionals: Prescribing Information |
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Acid Controller Original Strength | Rate | Add review | OTC | ||||
Generic name: famotidine systemic Drug class: H2 antagonists For consumers: dosage, interactions, side effects For professionals: Prescribing Information |
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Acid Reducer Maximum Strength | Rate | Add review | Rx/OTC | ||||
Generic name: famotidine systemic Drug class: H2 antagonists For consumers: dosage, interactions, side effects For professionals: Prescribing Information |
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Heartburn Relief | Rate | Add review | OTC | ||||
Generic name: famotidine systemic Drug class: H2 antagonists For consumers: dosage, interactions, side effects |
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Pepcid AC Chewable Tablets | 10 | 1 review | OTC | ||||
Generic name: famotidine systemic Drug class: H2 antagonists For consumers: dosage, interactions, side effects |
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cimetidine | 7.5 | 8 reviews | Rx/OTC | ||||
Generic name: cimetidine systemic Brand name: Tagamet HB Drug class: H2 antagonists For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph, Prescribing Information |
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Topics under GERD
- Barrett's Esophagus (16 drugs)
- Laryngopharyngeal Reflux (6 drugs)
Alternative treatments for GERD
The following products are considered to be alternative treatments or natural remedies for GERD. Their efficacy may not have been scientifically tested to the same degree as the drugs listed in the table above. However there may be historical, cultural or anecdotal evidence linking their use to the treatment of GERD.
Learn more about GERD
- Gastroesophageal Reflux Disease (GERD or heartburn)
- Gastrointestinal Disorders
- Low Salicylate Diet
- Stomach / Heartburn Medications and Alcohol Interactions
Care guides
- Barrett Esophagus
- GERD (Gastroesophageal Reflux Disease)
- GERD (Gastroesophageal Reflux Disease) in Children
- GERD Care Notes
Symptoms and treatments
Medicine.com guides (external)
Legend
Rating | For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective). |
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Activity | Activity is based on recent site visitor activity relative to other medications in the list. |
Rx | Prescription only. |
OTC | Over-the-counter. |
Rx/OTC | Prescription or Over-the-counter. |
Off-label | This medication may not be approved by the FDA for the treatment of this condition. |
EUA | An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives. |
Pregnancy Category | |
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A | Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters). |
B | Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women. |
C | Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks. |
D | There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks. |
X | Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits. |
N | FDA has not classified the drug. |
Controlled Substances Act (CSA) Schedule | |
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M | The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication. |
U | CSA Schedule is unknown. |
N | Is not subject to the Controlled Substances Act. |
1 | Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision. |
2 | Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
3 | Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence. |
4 | Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
5 | Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4. |
Alcohol | |
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X | Interacts with Alcohol. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.