Prilosec OTC Interactions
There are 243 drugs known to interact with Prilosec OTC (omeprazole), along with 3 disease interactions. Of the total drug interactions, 25 are major, 170 are moderate, and 48 are minor.
- View all 243 medications that may interact with Prilosec OTC
- View Prilosec OTC disease interactions (3)
Most frequently checked interactions
View interaction reports for Prilosec OTC (omeprazole) and the medicines listed below.
- amlodipine
- amlodipine
- aspirin
- aspirin
- atorvastatin
- atorvastatin
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- gabapentin
- gabapentin
- hydrochlorothiazide
- ibuprofen
- ibuprofen
- levothyroxine
- levothyroxine
- lisinopril
- lisinopril
- metformin
- metformin
- prednisone
- prednisone
- trazodone
- trazodone
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
- Vitamin D3 (cholecalciferol)
- Zyrtec (cetirizine)
- Zyrtec (cetirizine)
Prilosec OTC disease interactions
There are 3 disease interactions with Prilosec OTC (omeprazole) which include:
Report options
More about Prilosec OTC (omeprazole)
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- Compare alternatives
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- Reviews (21)
- Side effects
- Dosage information
- During pregnancy
- Drug class: proton pump inhibitors
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Pepcid
Pepcid is used to treat ulcers in the stomach and for conditions where the stomach produces too ...
Prilosec
Prilosec (omeprazole) is used to treat symptoms of GERD and other conditions caused by excess ...
Rabeprazole
Rabeprazole is used for barrett's esophagus, duodenal ulcer, duodenal ulcer prophylaxis, erosive ...
Ranitidine
Ranitidine is used to treat and prevent ulcers in the stomach and intestines. Includes ranitidine ...
Lansoprazole
Lansoprazole is used to treat stomach and intestinal ulcers, erosive esophagitis and ...
Esomeprazole
Esomeprazole is used for barrett's esophagus, duodenal ulcer prophylaxis, erosive esophagitis ...
Pantoprazole
Pantoprazole is a proton pump inhibitor used to treat GERD, erosive esophagitis, and ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.