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Pantoprazole User Reviews & Ratings

Brand names: Protonix, Protonix IV

Pantoprazole has an average rating of 4.9 out of 10 from a total of 424 reviews on Drugs.com. 36% of reviewers reported a positive experience, while 48% reported a negative experience.

Reviews for Pantoprazole

  • Pumpsi
  • Taken for 1 to 2 years
  • April 8, 2021

For GERD "14 month ago my GI put me on 40mg Pantoprazole for Gerd and Esophagus erosion . My Gerd seemed better, but not resolved, but I continued taking it. Then came Covid 19 1 month later. More and more I felt really sick with bloat, joint pain , severe back pain and extreme tiredness and NO energy , headaches, depression and anxiety. Also blurry vision and brain fog. I thought, it was all due to stress because of Covid . My physical being changed so drastically during this time. Now for the first time I researched the side effects of this drug and the realization set in that these are probably all side effects from this drug! I will not take it any longer and hope that I might start feeling better ! Often I thought that I was on my death bed feeling so awful ! Could these have been all the side effects of this drug ?"

3 / 10
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  • Anonymous
  • April 26, 2021

For GERD "I got acid reflux and the doctor prescribed pantoprazole. The side effects are brain fog, ringing in my ear, weakness, depression and anxiety. The dizziness was so horrible until I passed out and my husband found me on the kitchen floor which is very terrifying. Then, they prescribed Ativan, Sertraline Hydrocloride and I was told to seek help from mental health. I am a health care worker for over more than 10 years and I can say I am a very healthy individual until I had the GERD issue. The Pantoprazole just so awful why they are even out in the market?? I just stopped taking all the medications and do some juicing and a good diet. I am at home now for medical EI. let's see how it goes. Hopes everything goes well and please say a prayer for me to get better!!!"

1 / 10
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305 Report
  • Tyler...
  • Taken for less than 1 month
  • July 19, 2021

For GERD "Started taking this after bad acid reflux, helped, with the acid reflux but started feeling very ill, muscle pains, muscle twitching, headaches, back pain, neck pain my abdominal pains. I dropped weight really fast, dry throat, nausea, didn't feel hungry, panic attacks/anxiety, depression, foggy head/troubles concentrating, troubles sleeping, ringing in my ears, my sugar levels also started to crash a lot two weeks in. My doctor thought it was my diabetes medication, while emergency thought it was all in my head when I expressed concern to this medication being the problem. Also ended up spending a lot of money being told to take other meds for anxiety/sleep, taking trips to the hospital, and being out of work. Would not recommend this medication"

1 / 10
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Frequently asked questions

  • Pjano
  • July 21, 2020

Protonix (pantoprazole) for GERD "I started taking protonix 40mg once daily after they took Zantac off the market. I started having a lot of stomach pain, gas, bloating, and watery diarrhea. It took me a while to figure out it was the protonix. I stopped taking it and replaced it with Pepcid complete once a day. Almost immediately those symptoms went away. I would be very careful taking this drug."

1 / 10
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  • Hotshot
  • Taken for 1 to 6 months
  • October 4, 2020

Protonix (pantoprazole) for GERD "I have GERD. I couldn't eat anything. I was give protonix by the ER. Pain stopped I changed my diet drastically and slowly weaned myself from Protonix. Prior to this I tried Zantac, Nexium and Prilosec however I choose not to take these meds anymore and stick to my diet of low fat, low carb, no salt, no sugar and no fast, frozen or processed foods and I have lost weight and feel great with no pain. I also avoid smoke. when I was first prescribed these medication I didn't like any of them. I don't feel it's a good idea to inhibit the bodies natural processes so I make better food choices"

6 / 10
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Are you taking this medicine?

  • James
  • Taken for less than 1 month
  • July 12, 2021

For GERD "I've been on Pantoprazole for 5 days. It got rid of my GERD. However, the side-effects are bad. I am dizzy and light-headed. I have a poor appetite, anxiety and brain-fog. Water tastes bad. I am bloated, weak and tired. I don't plan to continue taking the drug."

1 / 10
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  • Sunsh...
  • Taken for 1 to 6 months
  • April 22, 2021

For GERD "I was put on pantoprazole almost 2 months now . I first started and it seemed to be working. I just received my COVID vaccine and thought. I was having a bad reaction from the injection . I just out of the blue googled the side effects from pantoprazole and I have almost all of them. Crazy - I've been wondering why I'm so dizzy all the time with nausea, diarrhea, intense anxiety and more acid waking me up + gas and burping . I'm done !! Tired of trying meds ..that don't seem to work."

1 / 10
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  • Anna
  • Taken for less than 1 month
  • December 28, 2020

For GERD "I took this pantoprazole for less than 24 hours and I have to say it was not a good experience. I had heart racing, massive headache, an odd tingling sensation, shortness of breath, excessive fatigue, dry mouth, and anxiety. I’m feeling slightly better this morning, but woke up feeling dehydrated despite drinking my weight in fluids yesterday. I will say I had a reaction to another similar medication to this as well which is why I switched to this one, so I don’t know if my body is just sensitive to these types of meds or what. I will never take these or anything like it again and I’m surprised that they get away with saying reactions are rare when clearly that’s not true. I started taking a probiotic and that has helped so far I think. Just hoping it didn’t do any long term damage."

1 / 10
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  • Eva
  • Taken for less than 1 month
  • July 3, 2020

For Stomach Ulcer "The doctor prescribed this drug to heal my stomach after having nausea and no appetite. After taking this drug I have experience really bad side effects which have affected me so much. Depression and extreme crying, anxiety to the point of having chest pains and tight chest feeling, joint pain, pins and needles, fever, gas and bloating, extreme nausea and no desire to eat, abdominal pain, brain fog, weakness and tired, insomnia, headaches. This has made me go to the ER thinking something serious was wrong with me. Being off of this medication for 2 days and symptoms are subsiding but still present. I was finally able to regain some appetite and eat again. I am sharing my story to let others know of the serious side effects of this medication."

1 / 10
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161 Report
  • Jordan
  • January 6, 2020

For GERD "I told my ENT doctor that in the past year or two I had been losing my voice and had a kind of tired throat. Nothing severe but worrying. A GI doctor did an endoscopy and told me I had esophagitis and prescribed 40mg of Pantoprazole. On the 3rd or 4th day on Panto, I woke up with a burning sensation in my throat and a horrible acidic taste in my mouth. This was the end of November. It is now January 6 and I have been off the drug (including trying Omeprazole for 3 weeks, with no help) for a month and these NEW symptoms have not gone away. I have begged multiple GI doctors for help and none of them will admit this drug did this to me. None of them have given me any advice or recommended anything to help this, nor will they acknowledge the drug could cause this reaction. Life has been an absolute nightmare ever since taking Pantoprazole and I would highly suggest people try other options before trying it."

1 / 10
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  • ESB
  • Taken for less than 1 month
  • February 18, 2020

For GERD "I was prescribed 40 mg of Pantoprazole for GERD, the doctor prescribed me 30 tablets out of the 30 I’ve taken 22 and I’ve been having chest pain, shortness of breath, and very lightheaded(dizzy) like I’m going to pass out. I was just released from the cardiologist and everything was okay. So I decided to research patient reviews on this medicine and I’ve read I’m not the only one with these side effects. I’ve even experienced headaches daily with leg cramping. This medicine isn’t good for me and I wouldn’t want no one else having to get these side effects. I’ve been to the ER twice since taking this medicine. The medicine has me thinking I was having a heart attack, there was several other test ran for them to say everything is normal."

1 / 10
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  • Noodle
  • Taken for 1 to 6 months
  • January 16, 2019

Protonix (pantoprazole) for GERD "I have had acid reflux disease for four years. I tried prilosec. I lost thirty pounds to try to help my reflux, I changed my diet, and I took an extreme amount of rolaids. Nothing worked and I was miserable. Finally got my GP to listen and put me on this stuff after a family member recommendation. It is wonderful. It is like I never had reflux to begin with. It helped me get my life back. My only concern is the side-effects for long term use seem scary. But if I don't treat the reflux, I will end up with barrett's esophagus, which puts me between a rock and a hard place."

10 / 10
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  • Mili
  • Taken for less than 1 month
  • December 29, 2020

For GERD "My GI prescribed this medication for stomach pains and Acid Reflux. Now I have daily stomach pains, neck ache, upper back pain, headache and joint pain. OMG I feel miserable. I can't believe this drug is still being prescribed. Stopped cold turkey after 3 weeks of nightmare. Been off it for 4 days and still not completely better. Wonder how long the side effects will last...?"

1 / 10
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  • Canuck
  • Taken for 1 to 6 months
  • April 28, 2020

For GERD "Was having so much trouble with my stomach so finally started taking this pantoprazole. I had been living on Tums, so was so very happy to find it worked right away. Have had NO side affects whatsoever."

10 / 10
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  • Stone...
  • Taken for less than 1 month
  • July 16, 2021

For GERD "I was prescribed PANTOPRAZOLE (Protonix) by an Emergency Doctor. She said it was safe to take it. Day 1 gave me stomach pain, but it went away. DAY 2 I was fine, DAY 3 I was fine, until DAY 4. I started feeling dizzy. I immediately suspended the pill. I have feel the anxiety that everyone is referring to. Also, it gives you brain fog. I would highly recommend to first do some research before you take this pill. I was taking Nexium before with no side effects, however it works slowly.. I should have stick to it instead of switching to this horrendous pill. As of now, I will be waiting to wipe it off my system. Think again if you need to take this pill, there are other pills that can be less harmful."

1 / 10
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  • Betsy
  • October 18, 2019

For GERD "Got a pain in my stomach and went to the GI Doc. He did an endoscopy. He prescribed Pantoprazole before the procedure to reduce inflammation and it turned out I did not have any inflammation. Post procedure, he advised I keep taking it. Side effects were severe. I stopped taking it. I DID NOT HAVE GERD before this. The question is WHY are GI docs prescribing it with impunity! I now have GERD - a condition that I will have to live with for the rest of my life. THIS DRUG IS POISON!"

1 / 10
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  • Mila
  • October 18, 2019

For GERD "I've been having acid reflux for a couple of months now but it was never bad enough for me to want to take medication for it. My doctor had prescribed me pantoprazole but I never reached for it because I was wary about it and my symptoms were not severe. A week ago, my symptoms worsened slightly and I decided to give it a try. With each day that I took it, my acid reflux got worse and worse as well as my anxiety. I had intense nausea, an awful taste in my mouth, burning and squeezing sensations in my chest, and my throat was constantly tight. I thought that maybe it would get better but my symptoms worsened so much that by the 3rd day, I couldn't tolerate it anymore. I stopped taking the pantoprazole and it's been 3-4 days ever since, and I'm still battling the symptoms the drug worsened. I know this drug may work for some people but it definitely didn't work for me, and I'd recommend to not take it."

1 / 10
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  • Mano
  • April 4, 2020

For Stomach Ulcer "Currently taking pantoprazole 40mg twice daily for a bit over 2 months now, for treatment of a possible ulcer and as prophylaxis while on extensive anti-inflammatory medications for another condition. Works great as far as I can tell, and I can't think of any side negative effects except some very mild stomach upset within ~20 minutes to an hour after taking it. I'm unfortunately very prone to side effects from medications, so I figured I'd write this review to help reassure people who might be seeing all the negative reviews on here."

9 / 10
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113 Report
  • Jelle
  • Taken for less than 1 month
  • April 30, 2021

For GERD "I took 3x20mg tablets over the space of about 10 days. The first thing I started to notice was a pounding heartbeat and constant "hot" headache which progressed to dangerous levels of blood pressure, blurred vision, chest pains, waking in the night having panic attacks, pressure in the left ear and whirring/ringing sounds. Sensitivity to sound as well. I honestly thought I was going to have a heart attack. I'm so glad I found this page but I'm so angry with my doctor for suggesting I take 2x20mg per day knowing I have existing heart problem. I swear if I'd followed her advice I would've ended up in big trouble. It's been a week and I'm still experiencing the side effects."

1 / 10
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  • Roxy
  • Taken for less than 1 month
  • July 28, 2021

For GERD "So I've been taking this machine for about a month now and it was helping me so much I was amazed. But then I started having problems where I thought I was going crazy. Really bad head aches, neck and back pains just pains all over my body. Swelling in my legs and hands, my legs hurt. Ringing in my ears, panic attacks, anxiety. I feel the brain fogginess I just feel weird like something is always wrong . Tonight I finally googled the side effects to this Meds. And I'm seeing all the side effects that I'm having and its mind blowing. I've been to the dr. So many times for each problem they give me different meds for this and that and seeing all this I won't be taking it any longer and will be going back to my dr. Tomorrow thank you everyone for your comments on here its helped me so much. Oh I also have really bad dry throat, and weight gain."

1 / 10
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  • Monolu
  • Taken for less than 1 month
  • February 16, 2020

For GERD "Took pantoprazole 20mg for 10 days for GERD. It did reduce my stomach acid but gave me: constant pain/tightness in the chest and upper back, shortness of breath, overall body aches, feverish and fluey feeling. I stopped it and am looking for an alternative."

3 / 10
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  • Czech...
  • Taken for less than 1 month
  • June 22, 2014

Protonix (pantoprazole) for GERD "After two days on Protonix (for GERD associated with adult-onset asthma) I ended up in the emergency room with extremely high blood pressure, fast, pounding pulse, severe headache, and severe anxiety. "

1 / 10
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177 Report
  • Ms B
  • Taken for less than 1 month
  • May 26, 2020

For GERD "I took this for GERD. I took twice. Horrible stomach ache/ gas. Also made me feel weird. I even started feeling super anxious and depressed.. started crying and feeling hopeless. Also did nothing for my symptoms. Although I wasn’t on them long enough to help. They made my reflux worse!! Horrible medication. Never again!"

1 / 10
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  • Never...
  • Taken for less than 1 month
  • June 15, 2020

For GERD "I have been taking Pantoprazole, 40mg for 25 days. Side effects, (which I hadn't realized were side effects until coming here), headaches like I've never experienced before and they have been almost constant for days. Racing pulse, palpitations, shortness of breath, constipation and now my sleep is being affected. It initially helped with the issues I was having but the headaches alone have been unbearable, like I have almost gone to the hospital unbearable."

2 / 10
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  • Suzette
  • February 8, 2014

Protonix (pantoprazole) for Stomach Ulcer "Had the most excruciating, painful ulcers that would wake me up in the middle of the night, and be so bad that I would double over from the pain. The Dr. gave me Protonix, and I swear after just taking the first pill that first night, the symptoms were gone! The pills were so effective, I only took them for 5 nights in a row, (even though he told me to finish the bottle) and just saved the other pills in case I might need them in the future. So far the pain has only come back once, from eating too much Tabasco sauce one night, but other than that, I've not been woken up with the pain since I've taken the pills. These pills were a God send for me. Extremely effective."

10 / 10
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158 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.