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Pantoprazole Pregnancy and Breastfeeding Warnings

Pantoprazole is also known as: Protonix, Protonix IV

Pantoprazole Pregnancy Warnings

Pantoprazole has been assigned to pregnancy category B by the FDA. Animal data have failed to reveal evidence of fetal harm after rats or rabbits were given doses 88 and 40 times the recommended human dose (based on body surface area), respectively. There are no data from controlled human studies. Pantoprazole should only be used during pregnancy when need has been clearly established.

See references

Pantoprazole Breastfeeding Warnings

Pantoprazole and its metabolites are excreted in the milk of rats. Pantoprazole has been detected in human milk in a study of a single nursing mother following a single 40 mg oral dose. Since many drugs are excreted in human milk, the manufacturer recommends that due to the potential for serious adverse reactions in nursing infants, a decision should be made to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.

See references

References for pregnancy information

  1. "Product Information. Protonix (pantoprazole)" Wyeth-Ayerst Laboratories, Philadelphia, PA.

References for breastfeeding information

  1. Adamek RJ, Bethke TD "Cure of Helicobacter pylori infection and healing of duodenal ulcer: comparison of pantoprazole-based one-week modified triple therapy versus two-week dual therapy. The International Pantoprazole HP Study Group." Am J Gastroenterol 93 (1998): 1919-24
  2. "Product Information. Protonix (pantoprazole)" Wyeth-Ayerst Laboratories, Philadelphia, PA.

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