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Pantoprazole User Reviews & Ratings (Page 2)

Brand names: Protonix, Protonix IV

Pantoprazole has an average rating of 5.0 out of 10 from a total of 435 reviews on Drugs.com. 37% of reviewers reported a positive experience, while 46% reported a negative experience.

Reviews for Pantoprazole

Commonly mentioned side effects
  • Suz...
  • February 8, 2014

Pantoprazole for Stomach Ulcer "Had the most excruciating, painful ulcers that would wake me up in the middle of the night, and be so bad that I would double over from the pain. The doctor gave me Protonix, and I swear after just taking the first pill that first night, the symptoms were gone! The pills were so effective, I only took them for 5 nights in a row, (even though he told me to finish the bottle) and just saved the other pills in case I might need them in the future. So far the pain has only come back once, from eating too much Tabasco sauce one night, but other than that, I've not been woken up with the pain since I've taken the pills. These pills were a godsend for me. Extremely effective."

10 / 10
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172 Report
  • Eli...
  • July 10, 2016

Pantoprazole for Erosive Esophagitis "I just started Protonix 6 days ago. I feel beat up. Does the Propofol used to do the procedure hang on for this many days? If it doesn't, then the Protonix is causing several symptoms. Lethargy, Dizziness, Dry mouth. And last and worst is constant ringing in my ears. It's getting very annoying. Has anyone else experienced this crazy ear side effect?"

2 / 10
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142 Report
  • Bea...
  • Taken for 5 to 10 years
  • October 30, 2018

Pantoprazole for GERD "I've been on Protonix for about 6 years and, to put it simply, it works perfectly for me without any side effects. If I don't take it, I have constant, severe heartburn (I have a hiatal hernia, gastritis, and GERD that resulted from an H. pylori infection that went undetected for what I assume is several years). When I do take it, I can eat literally anything and not get heartburn."

10 / 10
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108 Report

Frequently asked questions

  • Lau...
  • Taken for 10 years or more
  • April 27, 2020

Pantoprazole for Barrett's Esophagus "After starting with OTC drugs for acid reflux for several years, it was necessary for me to begin a prescription drug. I have taken Pantoprazole for over 10 years with no side effects. Works very well."

10 / 10
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83 Report
  • Jil...
  • October 31, 2020

For GERD "Prescriptions for GERD did not work for me. Changing eating habits and choosing healthy foods helped with my GERD. I did a lot of research too about natural remedies. 1 tablespoon of ACV and 1 tablespoon organic raw honey on 8 oz of warm water cured my acid reflux symptoms/GERD. You can increase this to 2 tablespoons. I drink this first thing in the morning and whenever I have heartburn and acid reflux."

3 / 10
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74 Report

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  • Lat...
  • July 4, 2021

For GERD "I have been taking this medication for 3 days. Day 1: severe headache all day. Day 2: anxiety peaked through the roof from a funny feeling, and now Day 3 I am dizzy and feeling sick to my stomach, and of course, anxiety through the roof again because of the weird feeling I have. I did notice stomach pain decreased with eating oatmeal. I think this will be my last day taking medicine. Through this all, I’m still bloated and constantly burping as I was doing prior to taking the meds."

4 / 10
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63 Report
  • rv ...
  • April 16, 2013

Pantoprazole for GERD "I have taken it for about 7 years now. I never had stomach problems but got what they thought was an ulcer. Later endoscopy showed no ulcer, but signs of Barrett's esophagus. I also had hoarse voice, especially in the morning. pH study pointed to GERD. Long story short, no more hoarseness. Subsequent scopes show no signs of esophagus damage. Now for the bad. Very rarely, when I eat fast, I do get choking sensations that I did not ever have before. Also, if I run out of the medicine and/or miss a dose or two, wicked bad heartburn. Never had heartburn before. As long as I stay on it, I am good."

7 / 10
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149 Report
  • Rec...
  • Taken for 6 months to 1 year
  • August 11, 2021

For GERD "25-year-old male, no other medications. I started this medication in February of 2021 for gastritis while my doctor figured out what was really wrong. I have never had a panic attack or suffered from anxiety/depression before. Approximately a month after taking this medication, I began having several panic attacks a day and freaking out over several things that I normally would never think twice about. After 2-3 more months on this med, the anxiety morphed into depression and intrusive thoughts. I had several other side effects that developed, such as weakness and ringing in my ears. After months of trial and error on testing, we finally figured out that my gallbladder was working at 19% and had it removed in June 2021. I talked with my doctor about these meds and how I suspected that it may have been causing all of my issues. My doctor agreed due to PPI causing B-12 and magnesium deficiency. Currently weaning off and hope to be done soon. I’ve already started feeling better in recent weeks."

1 / 10
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61 Report
  • AND...
  • Taken for less than 1 month
  • March 25, 2020

For GERD "I've been prescribed 40 mg of Protonix twice a day for severe acid reflux. Ever since starting on this medicine, it's been a nightmare. I have side effects of severe migraine in the back of my head, neck, and upper back, and joint pain. I'm a 31-year-old male and have never experienced anything like this in my life. The pain is unbearable. I just called to see what they can do for me. I'm waiting for a response, but I'm definitely not taking these anymore. I don't take any other medication, so I'm almost certain it's the medication."

1 / 10
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  • Lpe...
  • Taken for less than 1 month
  • June 9, 2021

For Gastritis/Duodenitis "Can anyone tell me how long the side effects last from this medicine? I took it for 12 days. During the second week, I started waking up crying and feeling depressed every morning. I have more anxiety. I started having stomach pain, and one day I had severe nausea. Also, I was dealing with some loss of appetite, and that’s gotten worse. I also experienced brain fog and extreme exhaustion and fatigue, like I couldn’t keep my eyes open. I think that PPIs can be extremely dangerous for some people. How can a medicine that’s supposed to heal bring so much destruction to your body? Ugh. I want to figure out something natural to take."

1 / 10
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59 Report
  • Jen...
  • Taken for 6 months to 1 year
  • October 7, 2018

Pantoprazole for GERD "I have both IBS and Gastritis. Protonix has been a complete game changer for me. Without it, I have chronic nausea, difficulties tolerating food, vomiting, low energy, and headache. My days were very difficult prior to being prescribed this med. I feel incredibly better."

10 / 10
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90 Report
  • Tee...
  • December 17, 2015

Pantoprazole for GERD "This was the worst medication I have ever taken. I was just prescribed this medication last week. After being on it for only 2 days, I stopped. Headache was unbearable. I thought I was going to have to go to the hospital to get a CAT scan until I realized it was probably the Protonix. Then there was the nausea that came along as well. Five days later, I'm still nauseous, but used ginger to help with that. Overall, I will never use this medicine again."

1 / 10
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120 Report
  • Anu...
  • October 2, 2020

For GERD "Took this stuff for 4 months on my GI's advice. I absolutely felt pathetic while I was on it (stomach cramps, constipation, dizziness, headaches, and more). Finally, the day arrived when the GI said to stop doing it (cold turkey), oh boy! It made my life miserable from that day. My B12 went super low (close to 100), I developed gastritis, and my GI wanted me to do Prilosec now. What an idiot! Started Pepcid now to manage the acid rebound from my initial dosage of 4 months. Never ever going back on this rubbish again."

1 / 10
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64 Report
  • bor...
  • Taken for 2 to 5 years
  • November 14, 2015

Pantoprazole for GERD "Unfortunately I have suffered with very serious GERD for 28 years, and it has been awful. I have tried every prescription medicine out there, and none of them work for me like Protonix does. I feel very close to a normal human being on this medication, but none of the others lived up to Protonix. I received a horrible notice from our health insurance provider this past week, and after December 31, 2015, they will no longer cover this drug. Their only suggestion for me with severe reflux is to try something else. I have tried EVERYTHING else on the market, and nothing works but Protonix. NOTHING! I am so sick with the GERD when I am off this medicine, I am pretty much housebound because I am so sick. For me, it is a miracle drug!"

10 / 10
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115 Report
  • MDa...
  • Taken for less than 1 month
  • June 20, 2019

For GERD "Got prescribed this pantoprazole a month after getting treated for H. pylori. Did nothing at all to control the acid and was still taking Tums to stop the pain. A week after I started taking the drug, I had extreme nausea lasting a day and a half. I felt dizzy and weak. Couldn't eat anything apart from plain crackers and could only stomach water. Nausea only eased when I stopped taking the drug. Be wary of taking this drug, I wish I never took it at all."

1 / 10
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75 Report
  • why...
  • March 31, 2012

Pantoprazole for GERD "Worked at first to bring heartburn/acid reflux under control, however I had to stop taking it because it started causing severe stomach & abdominal pain. Now control through diet & Tums EX. The pain from the Protonix side effect was terrible when it started happening."

1 / 10
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131 Report
  • MsS...
  • Taken for 1 to 6 months
  • May 17, 2020

Pantoprazole for GERD "I took this for about 2 and a half months. Halfway through, I told my Dr it wasn't working. He said I was under stress. Not. Then I developed a hot, itchy rash on my arms and face. They told me to stop taking it and start Nexium. I didn't because, to me, they seem to have the same risk. Being off Protonix is almost as bad as being on it. Terrible acid reflux. I am sleeping sitting up, I can't eat very much, I can hardly wake up and start falling asleep around 7 PM, and I have had a headache off and on for 3 days. Going to an internal medicine specialist next because I’d like to know the reason for the reflux I have had for 1.5 years, not just take a medication."

2 / 10
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70 Report
  • gui...
  • Taken for 1 to 6 months
  • April 19, 2018

Pantoprazole for Barrett's Esophagus "After a short time on Protonix, I began to experience back pain that radiated to the sides of my back in the kidney area. Then blood turned up in my urine. Both symptoms are serious side effects listed and it says you should contact your doctor immediately. My doctor told me that she couldn't say if the drug was the cause. The lesson learned - do your own research and be vigilant."

4 / 10
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78 Report
  • Ter...
  • February 22, 2016

Pantoprazole for GERD "I had heartburn and a history of an ulcer, so my doctor put me on Protonix. When taking it daily, I feel great. However, with the new information about this kind of drug being linked to dementia and also that it can cause one to be addicted to it and cause rebound acid, I decided to stop it. I am on day 4, and now a mild constant burning is in my stomach and often backs up to my chest. I was given them for heartburn, but the doctor wrote gerd and later I developed GERD on days I tried not to take it. So, I am concerned about this all coming back by ten times worse. I am looking into a natural alternative first, as dementia is all around in my family, and my new holistic/medical doctor says this type of drug is dangerous."

4 / 10
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106 Report
  • Sev...
  • Taken for 1 to 2 years
  • September 22, 2014

Pantoprazole for Barrett's Esophagus "I was diagnosed with Barrett's Esophagus six years ago, and regularly used Prilosec for the past 8 years, but I occasionally still had severe heartburn. Like the last post, I too was prescribed a higher and higher dose until I was taking 4-6 pills a day, still getting occasional heartburn. Last year I started taking only 40 mg per day of Pantoprazole, and I seldom (less than once a month when I get careless with food and/or alcohol) have had heartburn at all. I highly recommend asking your doctor about this medication, if you suffer from long-term frequent heartburn and Prilosec no longer seems to work as well."

10 / 10
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111 Report
  • Che...
  • Taken for less than 1 month
  • October 15, 2021

For GERD "Doctor prescribed these to me 7 days ago for GERD. After the 3rd day, I had to go off of them. Every bone in my body hurt. I had heart palpitations late at night, even after taking my dose in the morning. I am already prone to anxiety, and this made my anxiety 100x worse. I would wake up in the middle of the night unable to go back to sleep. I could feel my heart rate elevated. Then the headaches came. I also had random crying spells that were not brought on by anything happening. I had to go off of them. The side effects immediately stopped the day I went off of them. These pills are horrible. I asked my doctor to take me off of them due to the side effects, and she didn't even believe me. She said, 'Well, you have anxiety, so that's all that is. It is not the pills.' It absolutely IS the pills!"

1 / 10
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48 Report
  • ell...
  • Taken for less than 1 month
  • December 13, 2019

For Gastritis/Duodenitis "Do not take this pantoprazole, it is bad for you. Avoid it at all costs, I mean it. I was supposedly diagnosed with gastritis. The doctor gave me pantoprazole. After the first few days, I started feeling throat tightness/lump feeling even after light exercise. Then, gradually worsened, and I felt it all day, every day. Also, had extreme nausea, had to go to the hospital. Been off it for 2 days now, and my throat is recovering and my nausea has also subsided. DO NOT TAKE THIS. It will make you feel awful, and it is hard to recover from it."

1 / 10
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67 Report
  • jbu...
  • July 19, 2010

Pantoprazole for Barrett's Esophagus "I was on Prilosec for about 9 years for acid reflux. For me, it was a miracle drug that gave me relief for acid reflux. My dosage was continually increased until I was taking 4 20mg pills a day (probably a problem with my acid reflux increasing). After having more problems, I had an endoscopy, which showed I had Barrett's Esophagus. I was prescribed Protonix (2 x 40mg pills/day). So far, Protonix has worked great. For me, it works better than the Prilosec did."

10 / 10
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126 Report
  • Bob...
  • Taken for less than 1 month
  • January 20, 2021

Pantoprazole for GERD "My stomach really started hurting on Dec 23rd. I’ve battled reflux many times over the years. I’m 57, but not like this. I started on pantoprazole on Monday, this morning my stomach is starting to feel a bit normal. I hope so, as I’ve had this gnawing nausea, although it has gotten slightly better at times since the 23rd. Even a few occasions felt like I never had it, but it didn’t last long. I have slight other symptoms, as you all know-heartburn, indigestion, slight feeling through-but it’s the stomach that worries me. Anyone have any thoughts about stomach nausea? I’d love to hear. And does it take the meds time to fully kick in? Thank you to everyone, nothing short of GOD's blessings always."

7 / 10
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51 Report
  • Jim...
  • Taken for 5 to 10 years
  • March 27, 2013

Pantoprazole for GERD "Started taking this about 8 years ago after developing an ulcer from taking Aleve. Was fine for a few years, with only flatulence and loose bowel movements. For the last 3 years, I started developing asthma symptoms (phlegm in throat and lungs, coughing). Stopping Protonix cleared it up. Took 1 pill again and the asthma started again. Too bad, I really liked this medication."

5 / 10
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109 Report

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