Generic Name: dexlansoprazole (DEX lan SOE pra zol)
Brand Name: Dexilant
What is Dexilant (dexlansoprazole)?
Dexlansoprazole is a proton pump inhibitor that decreases the amount of acid produced in the stomach.
Dexlansoprazole is used to treat heartburn caused by gastroesophageal reflux disease (GERD), and to heal erosive esophagitis (damage to the esophagus from stomach acid).
Dexlansoprazole may also be used for purposes not listed in this medication guide.
What is the most important information I should know about Dexilant (dexlansoprazole)?
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
What should I discuss with my healthcare provider before taking Dexilant (dexlansoprazole)?
Heartburn is often confused with the first symptoms of a heart attack. Seek emergency medical attention if you have chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating, and a general ill feeling.
You should not take dexlansoprazole if you are allergic to it, or if you also take a medicine that contains rilpivirine (Complera, Edurant, Odefsey).
To make sure dexlansoprazole is safe for you, tell your doctor if you have:
severe liver disease;
low bone mineral density (osteopenia); or
low levels of magnesium in your blood.
Taking a proton pump inhibitor such as dexlansoprazole may increase your risk of bone fracture in the hip, wrist, or spine. This effect has occurred mostly in people who have taken the medicine long term or at high doses, and in those who are age 50 and older. It is not clear whether dexlansoprazole is the actual cause of an increased risk of fracture.
This medicine is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
It is not known whether dexlansoprazole passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
Dexlansoprazole is not approved for use by anyone younger than 12 years old.
How should I take Dexilant (dexlansoprazole)?
Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Take this medicine with a full glass of water.
Dexlansoprazole may be taken with or without food.
Do not crush, chew, break, or open a delayed-release capsule. Swallow it whole.
If you are unable to swallow a delayed-release capsule whole: Open the capsule and sprinkle the medicine into a spoonful of applesauce. Swallow this mixture right away without chewing. Do not save the mixture for later use. Discard the empty capsule.
To heal erosive esophagitis and relieve heartburn, dexlansoprazole is usually given for up to 6 months in adults, and for 4 to 16 weeks in children ages 12 through 17. Follow your doctor's dosing instructions very carefully.
Take this medicine for the full prescribed length of time. Your symptoms may improve before the condition is fully treated.
This medicine can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using dexlansoprazole.
Dexlansoprazole can also cause you to have a false positive drug screening test. If you provide a urine sample for drug screening, tell the laboratory staff that you are taking dexlansoprazole.
Call your doctor if your symptoms do not improve, or if they get worse while using dexlansoprazole.
If you use dexlansoprazole for longer than 3 years, you could develop a vitamin B-12 deficiency. Talk to your doctor about how to manage this condition if you develop it.
Store at room temperature away from moisture and heat.
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking Dexilant (dexlansoprazole)?
This medicine can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.
Dexilant (dexlansoprazole) side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
severe stomach pain, diarrhea that is watery or bloody;
a seizure (convulsions);
sudden pain or trouble moving your hip, wrist, or back;
kidney problems--urinating more or less than usual, blood in your urine, swelling, rapid weight gain;
symptoms of low vitamin B-12 levels--pale skin, tingling or numbness, muscle weakness, feeling light-headed or short of breath, tiredness, mood changes; or
symptoms of low magnesium--dizziness, confusion; fast or uneven heart rate; tremors (shaking) or jerking muscle movements; feeling jittery;muscle cramps, muscle spasms in your hands and feet; cough or choking feeling.
Common side effects may include:
nausea, vomiting, stomach pain, gas;
mouth pain, sore throat; or
stuffy nose, sinus pain, or other cold symptoms.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect Dexilant (dexlansoprazole)?
Tell your doctor about all your current medicines and any you start or stop using, especially:
a diuretic or "water pill";
St. John's wort;
warfarin (Coumadin, Jantoven); or
HIV or AIDS medicine--atazanavir, nelfinavir, ritonavir, saquinavir.
This list is not complete. Other drugs may interact with dexlansoprazole, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
See also: Side effects (in more detail)
More about Dexilant (dexlansoprazole)
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Images
- Drug Interactions
- Compare Alternatives
- Support Group
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- En Español
- 119 Reviews – Add your own review/rating
- Generic Availability
- Drug class: proton pump inhibitors
Related treatment guides
Where can I get more information?
- Your pharmacist can provide more information about dexlansoprazole.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
- Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2012 Cerner Multum, Inc. Version: 13.01.
Date modified: September 05, 2017
Last reviewed: November 23, 2016