Dexlansoprazole use while Breastfeeding
Drugs containing Dexlansoprazole: Dexilant, Kapidex, Dexilant SoluTab
Medically reviewed by Drugs.com. Last updated on Sep 26, 2019.
Dexlansoprazole Levels and Effects while Breastfeeding
Summary of Use during Lactation
Dexlansoprazole is the R-enantiomer of the protein-pump inhibitor, lansoprazole. No information is available on the use of dexlansoprazole or lansoprazole during breastfeeding. However, lansoprazole has been used safely in newborn infants, so it is unlikely that the amount of dexlansoprazole in breastmilk would be harmful.
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
A retrospective claims database study in the United States found that users of proton pump inhibitors had an increased risk of gynecomastia.
One case of elevated serum prolactin and galactorrhea was reported in a 21-year-old man taking lansoprazole (the racemic form). When omeprazole was substituted for lansoprazole, the serum prolactin decreased to the normal range and galactorrhea ceased.
Alternate Drugs to Consider
1. He B, Carleton B, Etminan M. Risk of gynecomastia with users of proton pump inhibitors. Pharmacotherapy. 2019;39:614-8. PMID: 30865318
2. Izquierdo Prieto OM, Moreno Alia E, Rosillo Gonzalez A. [Galactorrhea induced by lansoprazole]. Aten Primaria. 2004;34:325-6. PMID: 15491529
CAS Registry Number
Proton Pump Inhibitors
LactMed Record Number
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More about dexlansoprazole
- Side Effects
- During Pregnancy
- Dosage Information
- Imprints, Shape & Color Data
- Drug Interactions
- En Español
- 210 Reviews
- Drug class: proton pump inhibitors
- FDA Alerts (3)