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Dexilant Dosage

Generic name: dexlansoprazole 30mg
Dosage form: capsule, delayed release; tablet, orally disintegrating, delayed release

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Recommended Dosage in Patients 12 Years of Age and Older

Table 1. Recommended DEXILANT Capsules Dosage Regimen by Indication in Patients 12 Years of Age and Older
Indication Dosage of DEXILANT Capsules Duration
Healing of EE One 60 mg capsule once daily. Up to 8 weeks.
Maintenance of Healed EE and Relief of Heartburn One 30 mg capsule once daily. Controlled studies did not extend beyond 6 months in adults and 16 weeks in patients 12 to 17 years of age.
Symptomatic Non-Erosive GERD One 30 mg capsule once daily. 4 weeks.

Dosage Adjustment in Patients with Hepatic Impairment for the Healing of Erosive Esophagitis

For patients with moderate hepatic impairment (Child-Pugh Class B), the recommended dosage is a 30 mg DEXILANT capsule once daily for up to eight weeks. The use of a DEXILANT capsule is not recommended in patients with severe hepatic impairment (Child-Pugh Class C) [see Use in Specific Populations (8.6)].

Important Administration Information

  • Missed doses: If a dose is missed, administer as soon as possible. However, if the next scheduled dose is due, do not take the missed dose, and take the next dose on time. Do not take two doses at one time to make up for a missed dose.

DEXILANT capsules

  • Take without regard to food.
  • Swallow whole; do not chew.
  • For patients who have trouble swallowing capsules, DEXILANT capsules can be opened and administered with applesauce as follows:
    1. Place one tablespoonful of applesauce into a clean container.
    2. Open capsule.
    3. Sprinkle intact granules on applesauce.
    4. Swallow applesauce and granules immediately. Do not chew granules. Do not save the applesauce and granules for later use.
  • Alternatively, the capsule can be administered with water via oral syringe or nasogastric (NG) tube.

    Administration with Water in an Oral Syringe

    1. Open the capsule and empty the granules into a clean container with 20 mL of water.
    2. Withdraw the entire mixture into a syringe.
    3. Gently swirl the syringe in order to keep granules from settling.
    4. Administer the mixture immediately into the mouth. Do not save the water and granule mixture for later use.
    5. Refill the syringe with 10 mL of water, swirl gently, and administer.
    6. Refill the syringe again with 10 mL of water, swirl gently, and administer.

    Administration with Water via a NG Tube (≥16 French)

    1. Open the capsule and empty the granules into a clean container with 20 mL of water.
    2. Withdraw the entire mixture into a catheter-tip syringe.
    3. Swirl the catheter-tip syringe gently in order to keep the granules from settling, and immediately inject the mixture through the NG tube into the stomach. Do not save the water and granule mixture for later use.
    4. Refill the catheter-tip syringe with 10 mL of water, swirl gently, and flush the tube.
    5. Refill the catheter-tip syringe again with 10 mL of water, swirl gently, and administer.
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