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Medications for Indigestion

Other names: Dyspepsia; Uncomfortable fullness after meals

Dyspepsia means "bad digestion" and is commonly known as indigestion. Dyspepsia affects as much as 1/4 of the adult population in the U.S. and is responsible for a significant number of doctor visits. Dyspepsia has many possible causes- some easily diagnosed and others difficult to define. Dyspepsia is persistent or recurring abdominal pain that's centered in the upper abdomen and that lasts more than four weeks. People with dyspepsia also may experience bloating, nausea, burping and a feeling of fullness that occurs soon after eating. Symptoms usually develop after meals.

Drugs used to treat Indigestion

The following list of medications are in some way related to or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
omeprazole 4.0 45 reviews
Rx/OTC C N

Generic name: omeprazole systemic

Brand names:  Prilosec, Prilosec OTC

Drug class: proton pump inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Prilosec 8.5 2 reviews
Rx C N

Generic name: omeprazole systemic

Drug class: proton pump inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

famotidine 4.6 13 reviews
Rx/OTC B N

Generic name: famotidine systemic

Brand names:  Pepcid, Pepcid AC, Heartburn Relief, Acid Controller Maximum Strength, Acid Controller Original Strength, Pepcid AC Chewable Tablets, Pepcid Oral Suspension …show all

Drug class: H2 antagonists

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Prilosec OTC 7.8 5 reviews
OTC C N

Generic name: omeprazole systemic

Drug class: proton pump inhibitors

For consumers: dosage, interactions, side effects

Pepto-Bismol 8.3 12 reviews
Rx/OTC N N

Generic name: bismuth subsalicylate systemic

Drug class: antidiarrheals

For consumers: dosage, interactions, side effects

Pepcid Rate Add review
Rx B N

Generic name: famotidine systemic

Drug class: H2 antagonists

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Milk of Magnesia 7.0 5 reviews
Rx/OTC N N

Generic name: magnesium hydroxide systemic

Drug class: antacids, laxatives

For consumers: dosage, interactions, side effects

Pepcid AC Rate Add review
OTC B N

Generic name: famotidine systemic

Drug class: H2 antagonists

For consumers: dosage, interactions, side effects

Kaopectate Rate Add review
Rx/OTC N N

Generic name: bismuth subsalicylate systemic

Drug class: antidiarrheals

For consumers: dosage, interactions, side effects

Heartburn Relief Rate Add review
OTC B N

Generic name: famotidine systemic

Drug class: H2 antagonists

For consumers: dosage, interactions, side effects

Tums Regular Strength 6.3 3 reviews
OTC N N

Generic name: calcium carbonate systemic

Drug class: antacids, minerals and electrolytes

For consumers: dosage, interactions, side effects

Acid Controller Maximum Strength Rate Add review
OTC B N

Generic name: famotidine systemic

Drug class: H2 antagonists

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Acid Controller Original Strength Rate Add review
OTC B N

Generic name: famotidine systemic

Drug class: H2 antagonists

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

calcium carbonate 7.5 11 reviews
OTC N N

Generic name: calcium carbonate systemic

Brand names:  Tums Regular Strength, Cal-Mint, Calci-Chew, Titralac, Tums Smoothies …show all

Drug class: antacids, minerals and electrolytes

For consumers: dosage, interactions, side effects

Mylanta 0.0 1 review
OTC N N

Generic name: aluminum hydroxide / magnesium hydroxide / simethicone systemic

Drug class: antacids

For consumers: dosage, interactions, side effects

Pepcid AC Chewable Tablets 9.0 1 review
OTC B N

Generic name: famotidine systemic

Drug class: H2 antagonists

For consumers: dosage, interactions, side effects

Pepcid Oral Suspension Rate Add review
Rx B N

Generic name: famotidine systemic

Drug class: H2 antagonists

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

aluminum hydroxide / magnesium hydroxide / simethicone 9.5 3 reviews
OTC N N

Generic name: aluminum hydroxide / magnesium hydroxide / simethicone systemic

Brand names:  Mylanta, Gelusil, Almacone, Di-Gel, Mi-Acid, Milantex, Mintox, Mintox Plus, Mylanta Maximum Strength, Rulox …show all

Drug class: antacids

For consumers: dosage, interactions, side effects

bismuth subsalicylate 7.8 14 reviews
Rx/OTC N N

Generic name: bismuth subsalicylate systemic

Brand names:  Pepto-Bismol, Kaopectate, Bismarex, Bismatrol, Bismatrol Maximum Strength, Kola-Pectin DS, Peptic Relief, Percy Medicine, Pink Bismuth …show all

Drug class: antidiarrheals

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Amphojel Rate Add review
Rx/OTC N N

Generic name: aluminum hydroxide systemic

Drug class: antacids, phosphate binders

For consumers: dosage, interactions, side effects

cimetidine 9.0 1 review
Rx/OTC B N X

Generic name: cimetidine systemic

Brand names:  Equaline Acid Reducer, Leader Heartburn Relief, Tagamet HB

Drug class: H2 antagonists

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Gaviscon Extra Strength 10 2 reviews
OTC N N

Generic name: aluminum hydroxide / magnesium carbonate systemic

Drug class: antacids

For consumers: dosage, interactions, side effects

magnesium oxide Rate Add review
Rx/OTC C N

Generic name: magnesium oxide systemic

Brand names:  Mag-Oxide, Phillips' Cramp-free, Uro-Mag

Drug class: minerals and electrolytes

For consumers: dosage, interactions, side effects

magnesium hydroxide 7.2 11 reviews
Rx/OTC N N

Generic name: magnesium hydroxide systemic

Brand names:  Milk of Magnesia, Phillips' Milk of Magnesia, Dulcolax Milk of Magnesia, Ex-Lax Milk of Magnesia …show all

Drug class: antacids, laxatives

For consumers: dosage, interactions, side effects

Phillips' Milk of Magnesia 8.2 5 reviews
Rx/OTC N N

Generic name: magnesium hydroxide systemic

Drug class: antacids, laxatives

For consumers: dosage, interactions, side effects

Topics under Indigestion

Alternative treatments for Indigestion

The following products are considered to be alternative treatments or natural remedies for Indigestion. Their efficacy may not have been scientifically tested to the same degree as the drugs listed in the table above. However there may be historical, cultural or anecdotal evidence linking their use to the treatment of Indigestion.

Learn more about Indigestion

Care guides

Symptoms and treatments

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.