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Medications for Indigestion

Other names: Dyspepsia; Uncomfortable fullness after meals

About Indigestion:  Dyspepsia means "bad digestion" and is commonly known as indigestion. Dyspepsia affects as much as 1/4 of the adult population in the U.S. and is responsible for a significant number of doctor visits. Dyspepsia has many possible causes- some easily diagnosed and others difficult to define. Dyspepsia is persistent or recurring abdominal pain that's centered in the upper abdomen and that lasts more than four weeks. People with dyspepsia also may experience bloating, nausea, burping and a feeling of fullness that occurs soon after eating. Symptoms usually develop after meals.

Drugs Used to Treat Indigestion

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
omeprazole C N 12 reviews
7.0

Generic name: omeprazole systemic

Brand names:  Prilosec, Prilosec OTC

Drug class: proton pump inhibitors

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

ranitidine B N 14 reviews
7.0

Generic name: ranitidine systemic

Brand names:  Zantac, Zantac 150, Deprizine, Acid Relief, Berkley and Jensen Acid Reducer Maximum Strength, Careone Acid Reducer, Equaline Heartburn Relief, Sunmark Acid Reducer Maximum Strength …show all

Drug class: H2 antagonists

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Prilosec C N 2 reviews
9.0

Generic name: omeprazole systemic

Drug class: proton pump inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Zantac B N 2 reviews
9.0

Generic name: ranitidine systemic

Drug class: H2 antagonists

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Pepto-Bismol N N 6 reviews
8.0

Generic name: bismuth subsalicylate systemic

Drug class: antidiarrheals

For consumers: dosage, interactions, side effects

Milk of Magnesia N N 3 reviews
9.0

Generic name: magnesium hydroxide systemic

Drug class: antacids, laxatives

For consumers: dosage, interactions, side effects

Prilosec OTC C N 4 reviews
7.0

Generic name: omeprazole systemic

Drug class: proton pump inhibitors

For consumers: dosage, interactions, side effects

Kaopectate N N Add review
10

Generic name: bismuth subsalicylate systemic

Drug class: antidiarrheals

For consumers: dosage, interactions, side effects

Pepcid B N Add review
2.0

Generic name: famotidine systemic

Drug class: H2 antagonists

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

famotidine B N 2 reviews
4.0

Generic name: famotidine systemic

Brand names:  Pepcid, Pepcid AC, Acid Controller Maximum Strength, Heartburn Relief, Acid Controller Original Strength, Pepcid AC Chewable Tablets, Pepcid AC Maximum Strength, Pepcid Oral Suspension …show all

Drug class: H2 antagonists

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Zantac 150 B N 4 reviews
6.0

Generic name: ranitidine systemic

Drug class: H2 antagonists

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Tums Regular Strength N N 2 reviews
7.0

Generic name: calcium carbonate systemic

Drug class: antacids, minerals and electrolytes

For consumers: dosage, interactions, side effects

Pepcid AC B N Add review Rate

Generic name: famotidine systemic

Drug class: H2 antagonists

For consumers: dosage, interactions, side effects

Mylanta N N Add review Rate

Generic name: aluminum hydroxide / magnesium hydroxide / simethicone systemic

Drug class: antacids

For consumers: dosage, interactions, side effects

bismuth subsalicylate N N 6 reviews
9.0

Generic name: bismuth subsalicylate systemic

Brand names:  Pepto-Bismol, Kaopectate, Bismarex, Bismatrol, Bismatrol Maximum Strength, Kapectolin (New Formula), Kola-Pectin DS, Maalox Total Relief, Peptic Relief, Pink Bismuth …show all

Drug class: antidiarrheals

For consumers: dosage, interactions,

For professionals: Prescribing Information

Tagamet B N X Add review Rate

Generic name: cimetidine systemic

Drug class: H2 antagonists

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph

Amphojel N N Add review Rate

Generic name: aluminum hydroxide systemic

Drug class: antacids, phosphate binders

For consumers: dosage, interactions, side effects

aluminum hydroxide / magnesium hydroxide / simethicone N N Add review Rate

Generic name: aluminum hydroxide / magnesium hydroxide / simethicone systemic

Brand names:  Mylanta, Gelusil, Alamag Plus, Almacone, Di-Gel, Maalox Advanced Regular Strength, Mi-Acid, Milantex, Mintox, Mintox Plus, Mylanta Maximum Strength, Rulox …show all

Drug class: antacids

For consumers: dosage, interactions,

calcium carbonate N N 8 reviews
7.0

Generic name: calcium carbonate systemic

Brand names:  Tums Regular Strength, Titralac, Cal-Mint, Calci-Chew, Tums Smoothies …show all

Drug class: antacids, minerals and electrolytes

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts

magnesium hydroxide N N 8 reviews
8.0

Generic name: magnesium hydroxide systemic

Brand names:  Milk of Magnesia, Phillips' Milk of Magnesia, Dulcolax Milk of Magnesia, Ex-Lax Milk of Magnesia …show all

Drug class: antacids, laxatives

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts

Deprizine B N Add review Rate

Generic name: ranitidine systemic

Drug class: H2 antagonists

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Phillips' Milk of Magnesia N N 5 reviews
8.0

Generic name: magnesium hydroxide systemic

Drug class: antacids, laxatives

For consumers: dosage, interactions, side effects

Acid Controller Maximum Strength B N Add review Rate

Generic name: famotidine systemic

Drug class: H2 antagonists

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Acid Relief B N Add review Rate

Generic name: ranitidine systemic

Drug class: H2 antagonists

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Berkley and Jensen Acid Reducer Maximum Strength B N Add review Rate

Generic name: ranitidine systemic

Drug class: H2 antagonists

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

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Topics under Indigestion

  • GERD (129 drugs in 3 topics)

Alternative treatments for Indigestion

The following products are considered to be alternative treatments or natural remedies for Indigestion. Their efficacy may not have been scientifically tested to the same degree as the drugs listed in the table above. However there may be historical, cultural or anecdotal evidence linking their use to the treatment of Indigestion.

Learn more about Indigestion

Micromedex® Care Notes

Mayo Clinic Reference

Legend

Off Label This medication may not be approved by the FDA for the treatment of this condition.
Prescription Only / Over the Counter
Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Pregnancy
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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