Skip to main content

User Reviews for Omeprazole to treat Indigestion

Also known as: Prilosec, Prilosec OTC, Omesec

Omeprazole has an average rating of 4.3 out of 10 from a total of 39 ratings for the treatment of Indigestion. 26% of reviewers reported a positive effect, while 62% reported a negative effect.

Omeprazole Rating Summary

4.3/10 average rating

39 ratings from 41 user reviews.

Compare all 250 medications used in the treatment of Indigestion.

10
23%
9
3%
8
0%
7
8%
6
3%
5
3%
4
0%
3
13%
2
8%
1
41%

Reviews for Omeprazole

Smudgetootsie · Taken for 2 to 5 years March 10, 2021

“Omg I have just read these omeprazole reviews I just thank each and everyone of you for sharing your experiences as you have solved my health issues that I have been suffering for a year and a half probably longer. I even went to see my cardiologist and went through an angiogram as I felt so bad. Pains in my chest going through to my back and down my arms. My cardiologist said my arteries were all clear and these feelings must have been down to your sotalol beta blockers giving you side effects. I have just spent 4 nights in hospital trying to get to the bottom of these horrendous feelings. And by reading your reviews on Omeprazole I'm sure that's whats wrong with me. As you say it is one awful drug as its ruined my life for the past 2 years I would say. THANK YOU FOR SHARING”

1 / 10
Was this helpful?YesNo
Royalrider · Taken for 1 to 6 months August 13, 2020

“I have had heartburn for years. I was put on this omeprazole medication and it worked well for my heartburn. However after about 2 months or so I began to feel symptoms that I couldn't pin to one thing or another. Back aches, light headedness, fatigue, anxiety, shoulder pain and my rib cage felt like I got beat up. Also if felt like a basket ball was in my stomach. So I started chasing down side effects with the meds I take and started to see ALL these side effects tied to this drug. I am now on day 2 of not taking them. I just hope it is not too long before the side effects start to subside.”

3 / 10
Was this helpful?YesNo
dlb1954 · Taken for less than 1 month October 21, 2021

“After having a colonoscopy & EDG test done in October 2020. My doctor put me on Omeprazole. I took it for a week, until I read the side affects & chose to go off of it. Two months later I had a telephone doctor visit. I told him the side affects that I read. (Which he tried to brush them off). I took his word & tried the medication again. Only to realize it weakened my immune system & I ended up with shingles twice. I decided to do my own research & rely on natural supplements. Probiotic has been the best for me, along with my vitamins & herbal supplements. I would never take this medicine long term. Please do your research before taking any medication.”

2 / 10
Was this helpful?YesNo
Trish · Taken for less than 1 month May 9, 2020

“I've been talking Omeprazole for over a week now... I had a bad indigestion that lasted 4 days and the doctor told me to take the medication for 2 weeks. Right now I cant stop belching.. anything I eat gives so much gas (bloating too). I'm starting to thinking after reading this reviews that all my symptoms are because of omeprazole. I also feel nauseous before sleep .. and gives me this empty stomach feeling even after I ate.. (I think is all the gas). I wanna stop taking it but I don't want to get worse like some people are saying.”

3 / 10
Was this helpful?YesNo
Swiftdesire · Taken for less than 1 month December 1, 2020

“omeprazole caused extreme anxiety, feeling like I am life is a struggle, panic attacks, weight loss(10kgs in 5 weeks), palpitations, chest and arm pain on left side, brain fog, weakness and chills in legs and arms, dizziness, nausea, general fatigue, numbness, flatulence, joint pain (hip) after gentle walks, forgetfulness, fear of eating. I have stopped cold turkey after having come across reviews of Omeprazole and Protonix which I took as well. Took Omeprazole for 2 weeks, got these symptoms, told the doctor who changed the med to be pantoprazole(protonix). The last 2.5 months or so have been the worst of my life so far, it has taken a toll on my family and work life too. Doctor thought I might need anti depressants given all the anxiety but after around a week or so of stopping these, I am starting to feel a bit better. So, I am not going to take anti anxiety related meds. It is a vicious cycle, PPIs cause depression and then you take depression meds that are difficult to stop!”

1 / 10
Was this helpful?YesNo
Sunlight · Taken for 1 to 6 months September 30, 2021

“I was prescribed this for Indigestion and a mild concentric ring on esophagus. Was advised it was safe. I don't take any other medications and am healthy. Took for less than 4 months and the side effects started into the 4th month - Tinnitus, depression, anxiety, panic. Never knew what these were until I took this. Stopped it straight away after researching this. The withdrawals were horrendous. Depression, anxiety, kidney problems - 2 antibiotics to treat. Lost over 2 stone in weight the first few weeks as couldn't eat. Appetite returned after about 6 weeks. Went to see a functional medicine practitioner and am taking natural remedies which are helping hugely. I was glad to find this site and some other to know that this is what was causing all this. I am over 3 months of now and things are lifting. I read most people's recovery takes 3 to 6 months. I will never take this again and I will research anything I am ever advised to take with a degree of intense analysis.”

1 / 10
Was this helpful?YesNo
Lucy · Taken for less than 1 month July 9, 2021

“I just came back from the ER because I was about to pass out while driving in the hiway. I started feeling my arms getting numbed and shaking. I had a blood test and showed oxogen wasn't getting to my brain!.. I stopped that day taking this medication. I just had a second blood work and all my numbers are perfect. Stay away from this stuff!!”

1 / 10
Was this helpful?YesNo

Frequently asked questions

Crystal · Taken for less than 1 month April 18, 2021

“Was prescribed 20mg a day for indigestion and suspected stomach ulcer as having sharp pains upper stomach as well as heartburn and indigestion. Took capsule in the morning 30 mins before breakfast. Helped the indigestion but I have severe dizziness where I feel drunk or doped up, chest and stomach pain and my anxiety is through the roof. After 7 tablets I ended up going to hospital as I thought I was having a heart attack. I was examined and told my anxiety was driving my stomach and chest pain. That maybe the case, however the omeprazole was definitely driving the anxiety. I'm quitting this medication from tomorrow and pray I feel and get better.”

3 / 10
Was this helpful?YesNo
Dee · Taken for less than 1 month March 16, 2021

“Took this medicine for 8 days. On the third day started to feel awful. Brain fog, high anxiety and depression. Blurry vision and tingly feeling in hands and feet. I have now been off of it for 5 days and feeling like I’m losing my mind. I can’t work. I’m going to check my b12 levels tomorrow to determine if I am deficient. I hope this passes or eases up soon because I can barely even sleep. I thought it was a reaction to my first vaccine (Pfizer) until a friend told me omeprozole did this to him as well. What an awful drug. I’d recommend an all natural remedy over this any day.”

1 / 10
Was this helpful?YesNo
LWM December 26, 2019

“I was advised by my GP to take omeprazole 20mg daily. September 2019 my anxiety heightened to the point where I was unable to live on my own and I developed severe abdominal pain, muscle spasms, and extreme fatigue. I recently worked out that my acid levels had decreased drastically and I dropped from 8 Stone 7 to 7 stone 5. I ended up hospitalised on several occasions and only recently I decided to stop taking omeprazole. I’ve reintroduced more acidic foods back into my diet, I’m able to drink milk again and my stomach and mental health have improved immensely. My advice is that if you can control your stomach acid related problems thorough your diet then please use this as your first line of defence. Omeprazole just masks the symptoms and does not address the underlining issue. It’s still very early days for me but I hope and pray that I’m finally on the road to my recovery and I can start rebuilding my life once again.”

1 / 10
Was this helpful?YesNo
Unicorn blue August 7, 2020

“I would like to share my experience with omeprazole. Works great in reduce my stomach pain and hernia as I have IBS, but I forget important thinking from the every day life. I don't need to take it often, but when I do, as soon as I start taking it my short time memory goes weird. Not only me, my brother in law take this medication every single day, as he got heartburn. This is about 10 years ago. He lost his job, family and have personal problems with everybody because his funny memory that I 100% attribute to this medicine. Nobody believed me, yesterday I left a sandwich maker on...thanks goodness nothing happened. Never Ever in my life happened this to me, as I have good memory and I am extremely careful in everything I do.. 4 years using this medicine now an then... But I will try another alternative. Isn't fun at all...”

3 / 10
Was this helpful?YesNo
Jetty · Taken for 1 to 2 years May 8, 2020

“Was put on this horrific pill omeprazole 2018. What a nightmare I am going through. I lost 3 stone. Can't eat hardly any thing without it coming up. I have stopped taking it a week ago so hopefully I will feel better in the near future. Please be careful taking it. Does anybody know when I might start feeling better please”

1 / 10
Was this helpful?YesNo
fayfaith · Taken for 10 years or more September 21, 2017

Prilosec (omeprazole): “I have taken this medication for over two decades and it works well. Without it I wouldn't be able to hardly eat anything. If I run out and have to wait to get my refills .. It usually takes several days before any horrible symptoms come back. I try to get my meds before that happens. It really does help in making life so much better. You can eat in a normal fashion but sensible. I try to drink plenty of water, so my meds won't be to much of a strain on my bladder & kidneys and all my organs. I know without this medicine I couldn't even drink water without suffering the consequences.. it was that bad.”

10 / 10
Was this helpful?YesNo
Albert · Taken for less than 1 month June 24, 2018

Prilosec OTC (omeprazole): “I had terrible indigestion for about 3 years. It got progressively worse so that I had to take baking soda every night. On my recent trip to the USA, it was noticed that I would not eat late nor lots of food. A nurse at a BBQ gave me a packet of PRILOSEC 20mg. Back home I tried the medication. I was cured by taking only 1 tablet. I am finishing the packet, but had absolute no more problems nor symptoms after only 1 tablet. I have to say, that besides taking the medication, people also prayed for me.”

Was this helpful?YesNo
Anonymous August 4, 2019

“I have been taking omeprazole for 2 weeks and it was horrible, it cause my stomach to have more gas and bloat which is the opposite of what I feel it should do. It also cause constipation and loss of appetite I would never take this again after 1 day the abdominal pain got better! ”

Was this helpful?YesNo
Angry · Taken for 1 to 6 months January 4, 2021

“Took omeprazole for 5 months and am still reeling from the side effects that apparently don't exist! Random muscle spasms, complete pelvic/urinary failure including retention and inflammation which I previously didn't have! I haven't had reflux in a while and been off the meds for at least 5 months now, know what fixed my stomach? Diet filled with veg and cutting back on sugar and the western diet rubbish! Now I just need to fix my bladder and inflammation but I will never use a western medicine ever again!”

2 / 10
Was this helpful?YesNo
Yasmeen · Taken for 1 to 6 months June 27, 2020

“I started to have an irritation at the back of my throat which then became a bit sore. The doctor thought it could be acid reflux (Which I doubt it was) so gave me omeprazole. It worked for the first two days but then made my throat worse and my anxiety went through the roof. After three weeks went back to the doctors and was given nexium and not only did that work but my anxiety went right down. When my nexium finished my doctor put me back omeprazole and again my anxiety has increased. I have stopped taking it for the last 3 days now and I can now feel my anxiety coming down. Never going back to that. Will try through natural remedies instead. Would not recommend it at all”

1 / 10
Was this helpful?YesNo

More FAQ

Ands · Taken for 1 to 2 years November 30, 2019

“I have been experiencing extreme anxiety, depression, confusion, nausea and muscle spasms for a while now. I have been visiting my gp and haven't been able to find a cause. I have just found this page and now realize that omeprazole may be the cause, never thought it could be the cause because it seemed to help so much at first. Just hope stopping I can finally get back to normal.”

1 / 10
Was this helpful?YesNo
Randy October 11, 2019

“I've been taking Omeprazole for about five months for indigestion and GERD. The Omeprazole has flat put a stop to those problems but may be contributing to some other issues. During the time I've been taking Omeprazole, I've also been diagnosed as being anemic. In doing some reading on anemia I learned that one possible cause is a B12 deficiency. I also read that a contributing factor to B12 deficiency is using a Proton Pump Inhibitor (PPI). Omeprazole is a PPI. I'm not suggesting that Omeprazole is the sole cause of my anemia but I suspect it is a contributing factor. I quit taking Omeprazole about a week ago and there have definitely been some withdrawal symptoms. The indigestion has rebounded with a vengeance. It is worse than it was before I started on the Omeprazole. I've also been somewhat weak and light headed. These are known withdrawal symptoms that apparently can last from two weeks to three months. Omeprazole will surely stop indigestion but I'm not sure it's worth it.”

6 / 10
Was this helpful?YesNo
SJOR January 23, 2015

Prilosec OTC (omeprazole): “I took Prilosec for about 3 years. I began to experience a rapid heartbeat at night. I would wake up at night and have very rapid heartbeat for about 5 minutes. It finally dawned on me to try leaving off the Prilosec. I have been off now for 2 months and am having no more problems with my heart. I found that Pepcid is also good for indigestion and causes me no problem.”

10 / 10
Was this helpful?YesNo
minter davidson September 1, 2013

“I believe this is the best medication that I take. Since starting, over 2 years ago, I have had no heartburn, become very regular also. I take a 20mg cap every morning, and I don't eat breakfast. Just have coffee. (I am 66).”

10 / 10
Was this helpful?YesNo
Micca · Taken for less than 1 month June 22, 2016

“I cannot swallow well and my doctor advised me to take 2 capsules per day. I have been taking it for a week now and every day since that I am burping and bloating non stop. It is terrible feeling, feels like any moment I will throw up but I cannot. Feels like if I throw up I will feel better but I just cannot. Food or whatever "comes up" and just stops there. After few hours gets a bit better but I bloat all day :( help?”

5 / 10
Was this helpful?YesNo
JCsLight April 26, 2012

Prilosec (omeprazole): “In 2005 I had many tests. No clear diagnosis but Prilosec seemed to bring the burning under control for nearly 6 1/2 yrs. There was breakthrough pain, helped by diet. Though there were mood swings and muscle spasms. Never associated until reading these reviews.”

7 / 10
Was this helpful?YesNo
She · Taken for 1 to 6 months November 29, 2019

“Worst medication ever after doing some research, I do believe I got esophagus candida from it. Got sick with probably the stomach bug so doctor put me on Prilosec, took it for 3 months couldn't get better, didn't realize all the side effects nauseous, stomach pain, belching, gas, can't sleep because of the nausea and even my very first major panic attack. Ending up in the hospital a month ago, my stomach was perfect but not my esophagus so I took my last 20mg pill yesterday so I hope this all goes away soon.”

1 / 10
Was this helpful?YesNo
Bloaty · Taken for less than 1 month May 13, 2021

“I suddenly developed severe gas and bloating which persisted for about two months. My doctor prescribed omeprezole. It helped from the first day I took it. I don’t know why but this pill has completely cured my painful bloating.”

10 / 10
Was this helpful?YesNo

This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare professionals.

Learn more about Indigestion

IBM Watson Micromedex

Mayo Clinic Reference