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Medications for Ulcerative Colitis

The medications listed below are related to or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
mesalamine 7.1 105 reviews for mesalamine to treat Ulcerative Colitis Rx B N
Generic name:
mesalamine systemic
Brand names:
Lialda, Apriso, Asacol, Pentasa, Delzicol, Asacol HD, Rowasa, Zaldyon
Drug class:
5-aminosalicylates
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Lialda 6.9 28 reviews for Lialda to treat Ulcerative Colitis Rx B N
Generic name:
mesalamine systemic
Drug class:
5-aminosalicylates
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Humira 5.7 54 reviews for Humira to treat Ulcerative Colitis Rx B N
Generic name:
adalimumab systemic
Drug class:
antirheumatics, TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
budesonide 6.2 33 reviews for budesonide to treat Ulcerative Colitis Rx C N
Generic name:
budesonide systemic
Brand name:
Uceris
Drug class:
inhaled corticosteroids, glucocorticoids
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Entyvio 6.1 92 reviews for Entyvio to treat Ulcerative Colitis Rx B N
Generic name:
vedolizumab systemic
Drug class:
selective immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
sulfasalazine 5.4 22 reviews for sulfasalazine to treat Ulcerative Colitis Rx B N
Generic name:
sulfasalazine systemic
Brand names:
Azulfidine, Azulfidine EN-tabs
Drug class:
antirheumatics, 5-aminosalicylates
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
azathioprine 6.8 24 reviews for azathioprine to treat Ulcerative Colitis Rx D N
Generic name:
azathioprine systemic
Brand names:
Imuran, Azasan
Drug class:
antirheumatics, other immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Stelara 7.3 8 reviews for Stelara to treat Ulcerative Colitis Rx B N
Generic name:
ustekinumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Rinvoq 8.0 22 reviews for Rinvoq to treat Ulcerative Colitis Rx N
Generic name:
upadacitinib systemic
Drug class:
antirheumatics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Xeljanz 7.5 22 reviews for Xeljanz to treat Ulcerative Colitis Rx C N
Generic name:
tofacitinib systemic
Drug class:
antirheumatics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
vedolizumab 6.3 102 reviews for vedolizumab to treat Ulcerative Colitis Rx B N
Generic name:
vedolizumab systemic
Brand name:
Entyvio
Drug class:
selective immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
adalimumab 5.6 55 reviews for adalimumab to treat Ulcerative Colitis Rx B N
Generic name:
adalimumab systemic
Brand names:
Humira, Hyrimoz, Abrilada, Amjevita, Cyltezo, Hadlima, Hulio, Idacio, Simlandi, Yuflyma, Yusimry
Drug class:
antirheumatics, TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Apriso 6.9 20 reviews for Apriso to treat Ulcerative Colitis Rx B N
Generic name:
mesalamine systemic
Drug class:
5-aminosalicylates
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Remicade 6.8 47 reviews for Remicade to treat Ulcerative Colitis Rx B N
Generic name:
infliximab systemic
Drug class:
antirheumatics, TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
tofacitinib 7.3 24 reviews for tofacitinib to treat Ulcerative Colitis Rx C N
Generic name:
tofacitinib systemic
Brand name:
Xeljanz
Drug class:
antirheumatics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
ustekinumab 7.0 12 reviews for ustekinumab to treat Ulcerative Colitis Rx B N
Generic name:
ustekinumab systemic
Brand names:
Stelara, Imuldosa, Otulfi, Pyzchiva, Selarsdi, Steqeyma, Wezlana, Yesintek
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
balsalazide 7.3 18 reviews for balsalazide to treat Ulcerative Colitis Rx B N
Generic name:
balsalazide systemic
Brand name:
Colazal
Drug class:
5-aminosalicylates
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
upadacitinib 8.0 23 reviews for upadacitinib to treat Ulcerative Colitis Rx N
Generic name:
upadacitinib systemic
Brand name:
Rinvoq
Drug class:
antirheumatics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
mirikizumab 7.0 1 review for mirikizumab to treat Ulcerative Colitis Rx N
Generic name:
mirikizumab systemic
Brand name:
Omvoh
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Omvoh 7.0 1 review for Omvoh to treat Ulcerative Colitis Rx N
Generic name:
mirikizumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
risankizumab Rate Add review Rx N
Generic name:
risankizumab systemic
Brand name:
Skyrizi
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Skyrizi Rate Add review Rx N
Generic name:
risankizumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Tremfya Rate Add review Rx N
Generic name:
guselkumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Velsipity Rate Add review Rx N
Generic name:
etrasimod systemic
Drug class:
selective immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Asacol 5.4 11 reviews for Asacol to treat Ulcerative Colitis Rx B N
Generic name:
mesalamine systemic
Drug class:
5-aminosalicylates
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Pentasa 8.0 16 reviews for Pentasa to treat Ulcerative Colitis Rx B N
Generic name:
mesalamine systemic
Drug class:
5-aminosalicylates
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Imuran 7.2 13 reviews for Imuran to treat Ulcerative Colitis Rx D N
Generic name:
azathioprine systemic
Drug class:
antirheumatics, other immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Delzicol 9.0 2 reviews for Delzicol to treat Ulcerative Colitis Rx B N
Generic name:
mesalamine systemic
Drug class:
5-aminosalicylates
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Uceris 6.1 18 reviews for Uceris to treat Ulcerative Colitis Rx C N
Generic name:
budesonide systemic
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Asacol HD 6.5 2 reviews for Asacol HD to treat Ulcerative Colitis Rx B N
Generic name:
mesalamine systemic
Drug class:
5-aminosalicylates
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
hydrocortisone 2.5 2 reviews for hydrocortisone to treat Ulcerative Colitis Rx C N
Generic name:
hydrocortisone systemic
Brand names:
Cortenema, Cortef, Solu-Cortef
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
clonidine Off-label Rate Add review Rx C N X
Generic name:
clonidine systemic
Drug class:
antiadrenergic agents, centrally acting
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
Colazal 6.3 7 reviews for Colazal to treat Ulcerative Colitis Rx B N
Generic name:
balsalazide systemic
Drug class:
5-aminosalicylates
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
infliximab 6.3 57 reviews for infliximab to treat Ulcerative Colitis Rx B N
Generic name:
infliximab systemic
Brand names:
Remicade, Inflectra, Renflexis, Avsola, Ixifi, Zymfentra
Drug class:
antirheumatics, TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
dexamethasone 5.0 1 review for dexamethasone to treat Ulcerative Colitis Rx C N
Generic name:
dexamethasone systemic
Brand names:
De-Sone LA, Dexamethasone Intensol, Dxevo, ZoDex
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Rowasa 9.0 1 review for Rowasa to treat Ulcerative Colitis Rx B N
Generic name:
mesalamine systemic
Drug class:
5-aminosalicylates
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Simponi 5.6 9 reviews for Simponi to treat Ulcerative Colitis Rx B N
Generic name:
golimumab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Azulfidine 1.0 1 review for Azulfidine to treat Ulcerative Colitis Rx B N
Generic name:
sulfasalazine systemic
Drug class:
antirheumatics, 5-aminosalicylates
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Cortenema 1.0 1 review for Cortenema to treat Ulcerative Colitis Rx C N
Generic name:
hydrocortisone systemic
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
De-Sone LA Rate Add review Rx C N
Generic name:
dexamethasone systemic
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
Dexamethasone Intensol Rate Add review Rx C N
Generic name:
dexamethasone systemic
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
Dxevo Rate Add review Rx C N
Generic name:
dexamethasone systemic
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
ZoDex Rate Add review Rx C N
Generic name:
dexamethasone systemic
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
hydrocortisone Rate Add review Rx/OTC C N
Generic name:
hydrocortisone topical
Drug class:
topical steroids
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Inflectra 3.2 6 reviews for Inflectra to treat Ulcerative Colitis Rx B N
Generic name:
infliximab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Cortef Rate Add review Rx C N
Generic name:
hydrocortisone systemic
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Dipentum 7.0 3 reviews for Dipentum to treat Ulcerative Colitis Rx C N
Generic name:
olsalazine systemic
Drug class:
5-aminosalicylates
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Solu-Cortef Rate Add review Rx C N
Generic name:
hydrocortisone systemic
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Zeposia 8.0 3 reviews for Zeposia to treat Ulcerative Colitis Rx N
Generic name:
ozanimod systemic
Drug class:
selective immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Azulfidine EN-tabs Rate Add review Rx B N
Generic name:
sulfasalazine systemic
Drug class:
antirheumatics, 5-aminosalicylates
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
cyclosporine Off-label Rate Add review Rx C N
Generic name:
cyclosporine systemic
Drug class:
calcineurin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
Hyrimoz Rate Add review Rx B N
Generic name:
adalimumab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
mycophenolate mofetil Off-label Rate Add review Rx D N
Generic name:
mycophenolate mofetil systemic
Drug class:
selective immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
olsalazine 7.0 3 reviews for olsalazine to treat Ulcerative Colitis Rx C N
Generic name:
olsalazine systemic
Brand name:
Dipentum
Drug class:
5-aminosalicylates
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Renflexis Rate Add review Rx B N
Generic name:
infliximab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Zaldyon Rate Add review Rx B N
Generic name:
mesalamine systemic
Drug class:
5-aminosalicylates
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Abrilada Rate Add review Rx B N
Generic name:
adalimumab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Amjevita Rate Add review Rx B N
Generic name:
adalimumab systemic
Drug class:
antirheumatics, TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Avsola Rate Add review Rx B N
Generic name:
infliximab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Azasan Rate Add review Rx D N
Generic name:
azathioprine systemic
Drug class:
antirheumatics, other immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
corticotropin Off-label Rate Add review Rx C N
Generic name:
corticotropin systemic
Drug class:
corticotropin
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Off-label:
Yes
Cyltezo Rate Add review Rx B N
Generic name:
adalimumab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
golimumab 6.0 10 reviews for golimumab to treat Ulcerative Colitis Rx B N
Generic name:
golimumab systemic
Brand name:
Simponi
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Hadlima Rate Add review Rx B N
Generic name:
adalimumab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Hulio Rate Add review Rx B N
Generic name:
adalimumab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Idacio Rate Add review Rx B N
Generic name:
adalimumab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Ixifi Rate Add review Rx B N
Generic name:
infliximab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
Simlandi Rate Add review Rx B N
Generic name:
adalimumab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Yuflyma Rate Add review Rx B N
Generic name:
adalimumab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Yusimry Rate Add review Rx B N
Generic name:
adalimumab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Zymfentra Rate Add review Rx B N
Generic name:
infliximab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
etrasimod Rate Add review Rx N
Generic name:
etrasimod systemic
Brand name:
Velsipity
Drug class:
selective immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
guselkumab 8.0 1 review for guselkumab to treat Ulcerative Colitis Rx N
Generic name:
guselkumab systemic
Brand name:
Tremfya
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Imuldosa Rate Add review Rx B N
Generic name:
ustekinumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
Otulfi Rate Add review Rx B N
Generic name:
ustekinumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
ozanimod 8.0 3 reviews for ozanimod to treat Ulcerative Colitis Rx N
Generic name:
ozanimod systemic
Brand name:
Zeposia
Drug class:
selective immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Pyzchiva Rate Add review Rx B N
Generic name:
ustekinumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Selarsdi Rate Add review Rx B N
Generic name:
ustekinumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Steqeyma Rate Add review Rx B N
Generic name:
ustekinumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Wezlana Rate Add review Rx B N
Generic name:
ustekinumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Yesintek Rate Add review Rx B N
Generic name:
ustekinumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information

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Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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