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User Reviews for Tofacitinib to treat Ulcerative Colitis

Also known as: Xeljanz, Xeljanz XR

Tofacitinib has an average rating of 7.1 out of 10 from a total of 18 ratings for the treatment of Ulcerative Colitis. 61% of reviewers reported a positive effect, while 22% reported a negative effect.

Tofacitinib Rating Summary

7.1/10 average rating

18 ratings from 18 user reviews.

Compare all 116 medications used in the treatment of Ulcerative Colitis.

10
44%
9
6%
8
11%
7
0%
6
6%
5
11%
4
0%
3
6%
2
0%
1
17%

Reviews for Tofacitinib

Jarvygirl · Taken for 1 to 6 months February 4, 2019

Xeljanz (tofacitinib): “Xeljanz has been a miracle drug for me. Finally, after almost two years of horrible pain, severe diarrhea, etc.. I have a life again. I have tried so many pills, enemas, suppositories, biologics and everything failed me. The reason I rated it a 9 instead of 10 is because I still have an occasional day that I’m not doing well but I was in pain and had diarrhea EVERYDAY 20 plus times a day before Xeljanz. I never thought I would be so excited to say I finally have solid stool. Xeljanz started to work for me within two weeks, and is still working to this day. I have been on it four months. I highly recommend this medicine.”

9 / 10
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tray88 · Taken for less than 1 month February 22, 2019

Xeljanz (tofacitinib): “Have only been taking the 10mg twice a day for the last 5 days, yesterday my bathroom frequency went down from around 12-15 times a day down to just 2 trips yesterday!!!! Most amazing response I could have hoped for! Only bad part is the morning nausea I'm experiencing.”

10 / 10
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Ruby · Taken for 1 to 6 months April 5, 2020

Xeljanz (tofacitinib): “I’ve been on Xeljanz now for almost four months now. I was diagnosed with UC about 3 years ago and I’ve been in an almost constant flare since then with no medication or steroids able to keep it in check. After 3 weeks on Xeljanz I genuinely feel like a new person, my symptoms are almost entirely gone, and my energy levels improved substantially. I hadn’t been able to exercise outside without fear of being ‘caught’ for years and that has all totally changed now. I’ve been on 10mg twice a day and I’m about to drop that down to 5mg twice a day”

10 / 10
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Aiofe · Taken for 6 months to 1 year September 11, 2019

Xeljanz (tofacitinib): “After initial success with my first biologic, remicade, I had a year of remission. My UC came back full force but since I had stopped the remicade, my blood tests showed I antibodied to remicade. Then Humira-fail, Entyvio-fail, injecting 3 vials of sandostatin a day- fail. Then I got my entire colon/rectum removed and a Jpouch in late 2014. Since the surgery I’ve suffered severely with Pouchitis and Cuffitis. Ugh! So as soon as Xeljanz was available and reviewed by my doc he asked if I’d try it. I started in January. Now it’s 9 months later and I can finally say I have some real quality of life back!!! I never thought I’d get here. It took about 4-6 months of 5mg twice a day. Xeljanz giving me some life quality back! I’ve had some weird viruses so I’m staying on 5mg. Hoping for more positive post-release data!”

10 / 10
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review from UCpatient · Taken for 1 to 6 months August 11, 2020

Xeljanz (tofacitinib): “I've had a huge flare of Ulcerative Colitis for 2 years now. Used very different types of medicines. After using infliximab for half a year (which didn't help at all) I ended up in the hospital for a dexamethasone infusion for a few days. After taking prednisone for several months, I started on xeljanz 2 x 10 mg. I have to say, my UC is improving every day! No more blood in my stool within a month, but my stool is still a bit restless with gas, sometimes diarrhea and mucus. It takes a while for it to work properly the experts say (because the colon was so damaged). But it has already improved from going to the toilet 30 times a day to sleeping 5 times and nights! After 3 months on 2x10mg, I will soon be on 5mg twice daily. The only side effect is that you gain (a little) weight and also get tired (but that is a side effect of all these types of medicines). Bottom Line: The best-acting drug for my UC so far.”

8 / 10
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patcwin · Taken for 1 to 2 years March 4, 2021

Xeljanz (tofacitinib): “life saver for me since I started using it 2 years ago, it took a few weeks to a month to finally get me under control but once that happened It has been really good. I was very sick and now in remission. I only hope it stays this way. Just remember that it took a year and a half on prednisone and other drugs to keep me somewhat healthy and that it only took this a month and a half to get me back to where I could leave the house and not be scared.”

10 / 10
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Rosie · Taken for 6 months to 1 year February 6, 2020

Xeljanz (tofacitinib): “I was diagnosed with ulcerative colitis (UC) in 2012 after losing 20 lbs and going to the restroom a lot. I was extremely dehydrated. After I got out of hospital I was put this is on Asacol and predisone. I finally got into remission. After that time I started smoking cigarettes. I was in remission for 5 years without any medication. I decided to stop smoking and it thru me into a HUGE flare up with multiple BMs and blood. I tried Humira and that made things worse, Imuran gave me pancreatitis, Entyvio worked for a month, then stopped working. I started Xeljanz last year with 10 mgs twice daily. It was working well and then my doctor lowered my dose to 10 mg a day. I have been in a flare up since. However he put me on prednisone and it helped but it's tapering off and so my flare up is coming back. Other than Remnicade, I'm not sure what my other options are now?”

5 / 10
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Frequently asked questions

Concerned · Taken for 1 to 6 months March 15, 2021

Xeljanz (tofacitinib): “Was diagnosed with UC 2012, that was after 2 years of trying to self diagnose myself. Been on so many different meds. I've been on this medication for about 3 months 10mg 2 times a daily and I have to say it's been a ride. I was going to the bathroom a lot. Now I'm not going at all. Every week I have to take laxatives because I'm not going to the bathroom at all. It's causing weight gain. I'm extremely tired now as well. I can't keep my eyes open. I was driving my husband and I home and was almost in an accident as it hit me all of a sudden. Pulled over so he could drive but imagine what is would be like if I was alone. I'm so uncomfortable and the nausea and headache are unbearable. I work from home so it helps to step away from the computer but I'll say my symptoms on the meds aren't getting me anywhere I need to be.”

1 / 10
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Dee · Taken for less than 1 month December 30, 2019

Xeljanz (tofacitinib): “I had a flare of ulcerative colitis due to life stress. Was bleeding again. Xeljanz @ a dose of 10mg x day, it took 3 days to start getting no blood in stool. Quite amazing. I do have an ear infection though that I got from my small daughter so I'm taking precaution. Will follow up in a few months.”

10 / 10
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Annie · Taken for 1 to 6 months July 19, 2019

Xeljanz (tofacitinib): “I have Ulcerative Colitis and started Xeljanz last February for the bad joint pain that often accompanies Colitis. It worked almost instantly and my joints felt great. Unfortunately I developed 6 severe infections in under 4 months so I had to stop the Xeljanz. My joint pain is back so today my Rheumatologist started me back on Xeljanz at a half dosage. I was off it for 6 weeks and did not get one new infection.”

5 / 10
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Drew · Taken for 6 months to 1 year August 20, 2021

Xeljanz (tofacitinib): “Xeljanz was a miracle drug for me. 31 years old and I had UC for about 2 years and had tried numerous biologics with no success. The only thing that would put me into remission was high dosage steroids which I had been on for 2 years and had caused adrenal insufficiency for me. I was in the process of consulting with a gastro surgeon to have a J-pouch placed when my GI had me try Xeljanz and after about 6 weeks I went into complete remission. I take 10mg twice daily and have had 0 side effects after 8 months. This drug gave me my life back .”

10 / 10
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Tom · Taken for 6 months to 1 year October 19, 2020

“I was given tofacitinib in Aug 2019 after no response from infliximab, golimumab and ustekinumab. At first it work very well, my trips to the bathroom were reduced from about 10 times a day to 2-3, no blood. Lots of energy and normal appetite. I gained 6kg and felt normal again. All was going well until July this year when I took antibiotics. Ever since then blood has returned and slowly gotten worse. I am now being taken off this medication - it was great while it lasted!”

8 / 10
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Flewog · Taken for less than 1 month September 3, 2020

“Started tofacitinib for ulcerative colitis after I lost my long term remission to azathioprine and failed Humira. On tofacitinib I started to notice a difference to both my colitis symptoms and the joint pain I experience within 2 weeks. By the third week I developed the most severe headaches I have ever experienced and my blood pressure shot up. I had to stop the drug immediately due to the risks of clots and stroke that can be associated with it.”

3 / 10
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Pat · Taken for 2 to 5 years November 21, 2021

Xeljanz (tofacitinib): “I have been taking Xeljanz for UC for around 2 years now, nothing was working except for the prednisone, and that was killing me. This is the only drug I have taken that has worked. I do have some side effects but this is a miracle for me. 10 mg a day.”

10 / 10
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Ray · Taken for less than 1 month March 7, 2021

Xeljanz (tofacitinib): “I have had Colitis for over 5 years. I have tried quite a few other drugs and then I tried Xeljanz Worst drug I have have taken. Put me in the hospital for 6 days. Be careful”

1 / 10
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S kaur · Taken for 2 to 5 years September 17, 2020

Xeljanz (tofacitinib): “I have a very bad time before with my UC, I used all medicines , but when I start Xeljanz 5mg twice a day, my whole life changed, I feel very well, and thanks to xeljanz.”

10 / 10
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m · Taken for 1 to 6 months July 3, 2019

Xeljanz (tofacitinib): “I have been taking Xeljanz for my ulcerative colitis for 2 month now, it stops the blood but still having diarrhea around 6 to 8 times a day.”

6 / 10
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Abdu · Taken for 1 to 6 months March 25, 2020

Xeljanz (tofacitinib): “the medication Xeljanz did not help my UC at all. My colon inflammation remained the same and actually increased recently.”

1 / 10
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This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare professionals.

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