Uceris Foam Dosage

Dosage

The recommended dosage regimen is 1 metered dose administered rectally twice daily for 2 weeks followed by 1 metered dose administered rectally once daily for 4 weeks.

Administration Instructions

Advise patients:

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UCERIS rectal foam is only to be applied rectally. It is not for oral use.

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Before using UCERIS rectal foam, use the bathroom to empty your bowels.

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Each applicator is coated with a lubricant. If additional lubrication is needed, petrolatum or petroleum jelly can also be used.

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Warm the canister in the hands while shaking it vigorously for 10 to 15 seconds prior to use.

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UCERIS rectal foam can be used in a standing, lying or sitting position (e.g., while using the toilet).

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Apply UCERIS rectal foam in the morning and the evening for the first 2 weeks of treatment; then once daily in the evening for the next 4 weeks. When applied in the evening, use immediately prior to bedtime. Try not to empty your bowels again until the next morning.

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Avoid concomitant use of CYP3A4 inhibitors (e.g., ketoconazole, grapefruit juice) during treatment with UCERIS rectal foam.