Cortef Interactions
There are 642 drugs known to interact with Cortef (hydrocortisone), along with 23 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 88 are major, 517 are moderate, and 37 are minor.
- View all 642 medications that may interact with Cortef
- View Cortef alcohol/food interactions (2)
- View Cortef disease interactions (23)
Most frequently checked interactions
View interaction reports for Cortef (hydrocortisone) and the medicines listed below.
- albuterol
- Ativan (lorazepam)
- Benadryl (diphenhydramine)
- clonazepam
- Crestor (rosuvastatin)
- Cymbalta (duloxetine)
- DHEA (dehydroepiandrosterone)
- Florinef (fludrocortisone)
- fludrocortisone
- gabapentin
- Klonopin (clonazepam)
- levothyroxine
- lisinopril
- Lyrica (pregabalin)
- magnesium oxide
- melatonin
- metformin
- omeprazole
- pantoprazole
- prednisone
- Singulair (montelukast)
- Synthroid (levothyroxine)
- tramadol
- trazodone
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Zofran (ondansetron)
- Zoloft (sertraline)
- Zyrtec (cetirizine)
Cortef alcohol/food interactions
There are 2 alcohol/food interactions with Cortef (hydrocortisone).
Cortef disease interactions
There are 23 disease interactions with Cortef (hydrocortisone) which include:
- infections
- prematurity
- (+) tuberculin test
- cirrhosis
- depression/psychoses
- diabetes
- electrolyte imbalance
- fluid retention
- GI perforation
- hyperadrenocorticalism
- hyperlipidemia
- hypothyroidism
- liver disease
- MI
- myasthenia gravis
- myopathy
- ocular herpes simplex
- ocular toxicities
- osteoporosis
- PUD
- scleroderma
- strongyloidiasis
- thromboembolism
Report options
More about Cortef (hydrocortisone)
- Cortef consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (5)
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Generic availability
- Drug class: glucocorticoids
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
