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Dipentum Side Effects

Generic Name: olsalazine

Note: This document contains side effect information about olsalazine. Some of the dosage forms listed on this page may not apply to the brand name Dipentum.

For the Consumer

Applies to olsalazine: oral capsule

Along with its needed effects, olsalazine (the active ingredient contained in Dipentum) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur while taking olsalazine:

Rare

Some side effects of olsalazine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More Common

  • Abdominal or stomach pain or upset
  • diarrhea
  • loss of appetite

Less Common

For Healthcare Professionals

Applies to olsalazine: oral capsule

General

The most common adverse events were diarrhea and abdominal pain or cramps.

Gastrointestinal

Very common (10% or more): Diarrhea (11.1%), abdominal pain/cramps (10.1%)

Common (1% to 10%): Nausea, dyspepsia, bloating, vomiting, stomatitis

Uncommon (0.1% to 1%): Rectal bleeding, heartburn

Postmarketing reports: Abdominal pain upper, diarrhea with dehydration, dry mouth, epigastric discomfort, flare in symptoms, flatulence, increased blood in stool, pancreatitis, rectal bleeding, rectal discomfort[Ref]

Nervous system

Common (1% to 10%): Headache, vertigo/dizziness

Uncommon (0.1% to 1%): Lightheadedness

Postmarketing reports: Insomnia, paresthesia, peripheral neuropathy[Ref]

Cardiovascular

Postmarketing reports: Chest pains, heart block second degree, myocarditis, palpitations, pericarditis, hot flashes, hypertension, orthostatic hypotension

Musculoskeletal

Common (1% to 10%): Arthralgia/joint pain

Postmarketing reports: Chills, muscle cramps, myalgia[Ref]

Dermatologic

Common (1% to 10%): Rash, itching

Postmarketing reports: Erythema nodosum, alopecia, erythema, photosensitivity reaction, angioneurotic edema[Ref]

Other

Common (1% to 10%): Fatigue/drowsiness/lethargy

Postmarketing reports: Peripheral edema, tinnitus, fever, tremors

Respiratory

Postmarketing reports: Interstitial pulmonary disease, bronchospasm, dyspnea

Hepatic

Postmarketing reports: Granulomatous hepatitis, nonspecific reactive hepatitis, mild cholestatic hepatitis, ALT or AST elevated beyond the normal range, hepatic enzyme increased, hepatitis, increased bilirubin

Hematologic

Postmarketing reports: Anemia, eosinophilia, hemolytic anemia, leukopenia, lymphopenia, neutropenia, reticulocytosis, thrombocytopenia, aplastic anemia, pancytopenia[Ref]

Renal

Postmarketing reports: Interstitial nephritis, nephrotic syndrome

Immunologic

Common (1% to 10%): Upper respiratory infection

Genitourinary

Postmarketing reports: Dysuria, hematuria, proteinuria, urinary frequency

Psychiatric

Common (1% to 10%): Depression

Uncommon (0.1% to 1%): Insomnia

Postmarketing reports: Irritability, mood swings

Metabolic

Common (1% to 10%): Anorexia

Ocular

Postmarketing reports: Dry eyes, vision blurred, watery eyes

References

1. "Product Information. Dipentum (olsalazine)." Meda Pharmaceuticals, Somerset, NJ.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

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