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Antibiotics for Middle Ear Infections

The medications listed below are related to or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
amoxicillin 6.0 29 reviews for amoxicillin to treat Middle Ear Infections Rx B N
Generic name:
amoxicillin systemic
Brand name:
Amoxil
Drug class:
aminopenicillins
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
amoxicillin / clavulanate 4.7 54 reviews for amoxicillin / clavulanate to treat Middle Ear Infections Rx B N
Generic name:
amoxicillin / clavulanate systemic
Brand names:
Augmentin, Augmentin XR, Amoclan
Drug class:
penicillins/beta-lactamase inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
cefdinir 4.3 80 reviews for cefdinir to treat Middle Ear Infections Rx B N
Generic name:
cefdinir systemic
Drug class:
third generation cephalosporins
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Ciprodex 5.4 41 reviews for Ciprodex to treat Middle Ear Infections Rx C N
Generic name:
ciprofloxacin / dexamethasone otic
Drug class:
otic steroids with anti-infectives
For consumers:
dosage, side effects
For professionals:
Prescribing Information
Augmentin 4.8 32 reviews for Augmentin to treat Middle Ear Infections Rx B N
Generic name:
amoxicillin / clavulanate systemic
Drug class:
penicillins/beta-lactamase inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
azithromycin 5.9 16 reviews for azithromycin to treat Middle Ear Infections Rx B N
Generic name:
azithromycin systemic
Brand names:
Azithromycin Dose Pack, Zithromax
Drug class:
macrolides
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
cephalexin 9.3 4 reviews for cephalexin to treat Middle Ear Infections Rx B N
Generic name:
cephalexin systemic
Brand name:
Keflex
Drug class:
first generation cephalosporins
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
ofloxacin 1.0 1 review for ofloxacin to treat Middle Ear Infections Rx C N
Generic name:
ofloxacin otic
Drug class:
otic anti-infectives
For consumers:
dosage, side effects
For professionals:
Prescribing Information
Azithromycin Dose Pack 1.0 2 reviews for Azithromycin Dose Pack to treat Middle Ear Infections Rx B N
Generic name:
azithromycin systemic
Drug class:
macrolides
For consumers:
dosage, interactions, side effects
Amoxil Rate Add review Rx B N
Generic name:
amoxicillin systemic
Drug class:
aminopenicillins
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Cortisporin Otic 1.0 1 review for Cortisporin Otic to treat Middle Ear Infections Rx C N
Generic name:
hydrocortisone / neomycin / polymyxin b otic
Drug class:
otic steroids with anti-infectives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Zithromax 6.0 4 reviews for Zithromax to treat Middle Ear Infections Rx B N
Generic name:
azithromycin systemic
Drug class:
macrolides
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
clarithromycin 5.5 47 reviews for clarithromycin to treat Middle Ear Infections Rx C N
Generic name:
clarithromycin systemic
Brand name:
Biaxin XL
Drug class:
macrolides
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Keflex 9.0 2 reviews for Keflex to treat Middle Ear Infections Rx B N
Generic name:
cephalexin systemic
Drug class:
first generation cephalosporins
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
levofloxacin Off-label 5.3 22 reviews for levofloxacin to treat Middle Ear Infections Rx C N
Generic name:
levofloxacin systemic
Drug class:
quinolones and fluoroquinolones
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
Bactrim 6.7 6 reviews for Bactrim to treat Middle Ear Infections Rx D N X
Generic name:
sulfamethoxazole / trimethoprim systemic
Drug class:
sulfonamides
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
ciprofloxacin / dexamethasone 5.6 46 reviews for ciprofloxacin / dexamethasone to treat Middle Ear Infections Rx C N
Generic name:
ciprofloxacin / dexamethasone otic
Brand name:
Ciprodex
Drug class:
otic steroids with anti-infectives
For consumers:
dosage, side effects
For professionals:
Prescribing Information
sulfamethoxazole / trimethoprim 5.9 11 reviews for sulfamethoxazole / trimethoprim to treat Middle Ear Infections Rx D N X
Generic name:
sulfamethoxazole / trimethoprim systemic
Brand names:
Bactrim, Septra, SMZ-TMP DS, Co-trimoxazole, Septra DS, Sulfatrim Pediatric
Drug class:
sulfonamides
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
hydrocortisone / neomycin / polymyxin b 2.2 24 reviews for hydrocortisone / neomycin / polymyxin b to treat Middle Ear Infections Rx C N
Generic name:
hydrocortisone / neomycin / polymyxin b otic
Brand names:
Cortisporin Otic, Casporyn HC, Cortomycin, Cort-Biotic
Drug class:
otic steroids with anti-infectives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
cefuroxime 6.0 4 reviews for cefuroxime to treat Middle Ear Infections Rx B N
Generic name:
cefuroxime systemic
Brand names:
Ceftin, Zinacef
Drug class:
second generation cephalosporins
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
erythromycin 4.0 2 reviews for erythromycin to treat Middle Ear Infections Rx B N X
Generic name:
erythromycin systemic
Brand names:
Erythrocin, E.E.S. Granules, Ery-Tab, Eryc, EryPed, Erythrocin Lactobionate, PCE Dispertab
Drug class:
macrolides
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
ceftriaxone 8.9 8 reviews for ceftriaxone to treat Middle Ear Infections Rx B N
Generic name:
ceftriaxone systemic
Drug class:
third generation cephalosporins
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Ceftin 2.0 1 review for Ceftin to treat Middle Ear Infections Rx B N
Generic name:
cefuroxime systemic
Drug class:
second generation cephalosporins
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Suprax 10 1 review for Suprax to treat Middle Ear Infections Rx B N
Generic name:
cefixime systemic
Drug class:
third generation cephalosporins
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Augmentin XR Rate Add review Rx B N
Generic name:
amoxicillin / clavulanate systemic
Drug class:
penicillins/beta-lactamase inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
cefixime 10 1 review for cefixime to treat Middle Ear Infections Rx B N
Generic name:
cefixime systemic
Brand name:
Suprax
Drug class:
third generation cephalosporins
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Penicillin VK Rate Add review Rx B N
Generic name:
penicillin v potassium systemic
Drug class:
natural penicillins
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
trimethoprim Rate Add review Rx C N
Generic name:
trimethoprim systemic
Brand name:
Primsol
Drug class:
urinary anti-infectives
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Amoclan Rate Add review Rx B N
Generic name:
amoxicillin / clavulanate systemic
Drug class:
penicillins/beta-lactamase inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
ampicillin 5.0 1 review for ampicillin to treat Middle Ear Infections Rx B N
Generic name:
ampicillin systemic
Drug class:
aminopenicillins
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
cefaclor Rate Add review Rx B N
Generic name:
cefaclor systemic
Drug class:
second generation cephalosporins
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Septra Rate Add review Rx D N X
Generic name:
sulfamethoxazole / trimethoprim systemic
Drug class:
sulfonamides
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
SMZ-TMP DS Rate Add review Rx D N X
Generic name:
sulfamethoxazole / trimethoprim systemic
Drug class:
sulfonamides
For consumers:
dosage, interactions, side effects
cefprozil 4.3 4 reviews for cefprozil to treat Middle Ear Infections Rx B N
Generic name:
cefprozil systemic
Brand name:
Cefzil
Drug class:
second generation cephalosporins
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Co-trimoxazole Rate Add review Rx D N X
Generic name:
sulfamethoxazole / trimethoprim systemic
Drug class:
sulfonamides
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Cortisporin-TC Rate Add review Rx N N
Generic name:
colistin sulfate / hydrocortisone / neomycin / thonzonium bromide otic
Drug class:
otic steroids with anti-infectives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Erythrocin Rate Add review Rx B N X
Generic name:
erythromycin systemic
Drug class:
macrolides
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Septra DS 8.0 1 review for Septra DS to treat Middle Ear Infections Rx D N X
Generic name:
sulfamethoxazole / trimethoprim systemic
Drug class:
sulfonamides
For consumers:
dosage, interactions, side effects
Sulfatrim Pediatric Rate Add review Rx D N X
Generic name:
sulfamethoxazole / trimethoprim systemic
Drug class:
sulfonamides
For consumers:
dosage, interactions, side effects
Biaxin XL Rate Add review Rx C N
Generic name:
clarithromycin systemic
Drug class:
macrolides
For consumers:
dosage, interactions, side effects
Casporyn HC Rate Add review Rx C N
Generic name:
hydrocortisone / neomycin / polymyxin b otic
Drug class:
otic steroids with anti-infectives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
cefpodoxime Rate Add review Rx B N
Generic name:
cefpodoxime systemic
Drug class:
third generation cephalosporins
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Cortomycin Rate Add review Rx C N
Generic name:
hydrocortisone / neomycin / polymyxin b otic
Drug class:
otic steroids with anti-infectives
For consumers:
dosage, interactions, side effects
E.E.S. Granules Rate Add review Rx B N X
Generic name:
erythromycin systemic
Drug class:
macrolides
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Ery-Tab Rate Add review Rx B N X
Generic name:
erythromycin systemic
Drug class:
macrolides
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Eryc Rate Add review Rx B N X
Generic name:
erythromycin systemic
Drug class:
macrolides
For consumers:
dosage, interactions, side effects
EryPed Rate Add review Rx B N X
Generic name:
erythromycin systemic
Drug class:
macrolides
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Erythrocin Lactobionate Rate Add review Rx B N X
Generic name:
erythromycin systemic
Drug class:
macrolides
For consumers:
dosage, interactions, side effects
Otovel Rate Add review Rx N N
Generic name:
ciprofloxacin / fluocinolone otic
Drug class:
otic steroids with anti-infectives
For consumers:
dosage, side effects
For professionals:
Prescribing Information
PCE Dispertab Rate Add review Rx B N X
Generic name:
erythromycin systemic
Drug class:
macrolides
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
penicillin v potassium Rate Add review Rx B N
Generic name:
penicillin v potassium systemic
Brand name:
Penicillin VK
Drug class:
natural penicillins
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Primsol Rate Add review Rx C N
Generic name:
trimethoprim systemic
Drug class:
urinary anti-infectives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Tazicef Rate Add review Rx B N
Generic name:
ceftazidime systemic
Drug class:
third generation cephalosporins
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Zinacef Rate Add review Rx B N
Generic name:
cefuroxime systemic
Drug class:
second generation cephalosporins
For consumers:
dosage, interactions, side effects
Bicillin C-R Rate Add review Rx B N
Generic name:
penicillin g benzathine / procaine penicillin systemic
Drug class:
natural penicillins
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Bicillin C-R 900/300 Rate Add review Rx B N
Generic name:
penicillin g benzathine / procaine penicillin systemic
Drug class:
natural penicillins
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
ceftazidime Rate Add review Rx B N
Generic name:
ceftazidime systemic
Brand names:
Tazicef, Fortaz
Drug class:
third generation cephalosporins
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Cefzil Rate Add review Rx B N
Generic name:
cefprozil systemic
Drug class:
second generation cephalosporins
For consumers:
dosage, interactions, side effects
ciprofloxacin / fluocinolone 1.0 1 review for ciprofloxacin / fluocinolone to treat Middle Ear Infections Rx N N
Generic name:
ciprofloxacin / fluocinolone otic
Brand name:
Otovel
Drug class:
otic steroids with anti-infectives
For consumers:
dosage, side effects
For professionals:
Prescribing Information
colistin sulfate / hydrocortisone / neomycin / thonzonium bromide Rate Add review Rx N N
Generic name:
colistin sulfate / hydrocortisone / neomycin / thonzonium bromide otic
Brand names:
Cortisporin-TC, Coly-Mycin S
Drug class:
otic steroids with anti-infectives
For consumers:
interactions, side effects
Coly-Mycin S Rate Add review Rx N N
Generic name:
colistin sulfate / hydrocortisone / neomycin / thonzonium bromide otic
Drug class:
otic steroids with anti-infectives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Cort-Biotic Rate Add review Rx C N
Generic name:
hydrocortisone / neomycin / polymyxin b otic
Drug class:
otic steroids with anti-infectives
For consumers:
dosage, interactions, side effects
Fortaz Rate Add review Rx B N
Generic name:
ceftazidime systemic
Drug class:
third generation cephalosporins
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
penicillin g benzathine / procaine penicillin Rate Add review Rx B N
Generic name:
penicillin g benzathine / procaine penicillin systemic
Brand names:
Bicillin C-R, Bicillin C-R 900/300
Drug class:
natural penicillins
For consumers:
dosage, interactions, side effects

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Frequently asked questions

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Topics under Middle Ear Infections

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Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

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