Ofloxacin Otic Dosage
Medically reviewed by Drugs.com. Last updated on Aug 14, 2023.
Applies to the following strengths: 0.3%
Usual Adult Dose for:
Usual Pediatric Dose for:
Additional dosage information:
Usual Adult Dose for Acute Otitis Externa
Usual dose: Instill 10 drops into the affected ear(s) once a day
Duration of therapy: 7 days
Comments:
- Patients should lie with the affected ear upward before administration. Once instilled, the patient should remain in this position for at least 5 minutes.
- If both ears are affected, this procedure should be repeated for the opposite ear.
Use: Treatment of otitis externa due to Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus
Usual Adult Dose for Otitis Media
Usual dose: Instill 10 drops into the affected ear(s) 2 times a day
Duration of therapy: 14 days
Comments:
- Patients should lie with the affected ear upward before administration. Once instilled, the tragus should be pumped inward 4 times, and the patient should remain in this position for at least 5 minutes.
- If both ears are affected, this procedure should be repeated for the opposite ear.
Use: Treatment of chronic suppurative otitis media in patients with perforated tympanic membranes due to Proteus mirabilis, Pseudomonas aeruginosa, or Staphylococcus aureus
Usual Pediatric Dose for Acute Otitis Externa
6 months to 13 years:
- Usual dose: Instill 5 drops into the affected ear(s) once a day
- Duration of therapy: 7 days
13 years and older:
- Usual dose: Instill 10 drops into the affected ear(s) once a day
- Duration of therapy: 7 days
Comments:
- Patients should lie with the affected ear upward before administration. Once instilled, the patient should remain in this position for at least 5 minutes.
- If both ears are affected, this procedure should be repeated for the opposite ear.
Use: Treatment of otitis externa due to Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus
Usual Pediatric Dose for Otitis Media
1 to 12 years old:
- Usual dose: Instill 5 drops into the affected ear(s) 2 times a day
- Duration of therapy: 10 days
12 years and older:
- Usual dose: Instill 10 drops into the affected ear(s) 2 times a day
- Duration of therapy: 14 days
Comments:
- Patients should lie with the affected ear upward before administration. Once instilled, the tragus should be pumped inward 4 times, and the patient should remain in this position for at least 5 minutes.
- If both ears are affected, this procedure should be repeated for the opposite ear.
Uses:
- Treatment of acute otitis media in patients 1 to 12 years old with tympanostomy tubes due to Haemophilus influenzae, Moraxella catarrhalis, Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus pneumoniae
- Treatment of chronic suppurative otitis media in patients 12 years and older with perforated tympanic membranes due to Proteus mirabilis, P aeruginosa, and S aureus
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Precautions
Safety and efficacy have not been established in patients younger than 6 months (otitis externa), 1 year (tympanostomy tubes and acute otitis media), and 12 years (chronic suppurative otitis media and perforated tympanic membranes).
Consult WARNINGS section for additional precautions.
Dialysis
Data not available
Other Comments
Administration advice:
- Patients should shake the bottle well before use.
- The vial should be warmed in their hands for 1 to 2 minutes prior to administration to avoid dizziness associated with instillation of a cold solution into the ear canal.
Storage requirements:
- This drug should be protected from light when not in use
General:
- Each drop of solution delivers 0.05 mL, which is equivalent to 0.15 mg of this drug.
- Limitations of use: This drug is indicated for otic use only. It is not indicated for ophthalmic use or injection.
Patient advice:
- Tell patients that this drug is for otic use only.
- Patients should be instructed to wash their hands before and after applying this drug.
- Caution patients to warm the vial in the hands for 1 to 2 minutes to prevent dizziness during administration.
- Patients should be encouraged to avoid missing doses and complete the entire course of therapy.
- Patients should be advised to immediately report any signs/symptoms of hypersensitivity reactions.
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