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Ofloxacin otic Side Effects

For the Consumer

Applies to ofloxacin otic: otic solution

Along with its needed effects, ofloxacin otic may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking ofloxacin otic:

Less Common

  • Burning, itching, redness, skin rash, swelling, or other sign of irritation not present before use of this medicine

Check with your doctor as soon as possible if any of the following side effects occur while taking ofloxacin otic:

Less Common


Some side effects of ofloxacin otic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less Common

  • Change in taste
  • earache
  • numbness or tingling

For Healthcare Professionals

Applies to ofloxacin otic: otic solution


Very common (10% or more): Application site reaction (up to 16.8%)[Ref]


Common (1% to 10%): Pruritus, rash

Frequency not reported: Seborrhea, dermatitis, eczema, erythematous rash, follicular rash, flushing, urticaria[Ref]

Nervous system

Common (1% to 10%): Paresthesia, dizziness

Uncommon (0.1% to 1%): Headache, vertigo

Frequency not reported: Tremor, hypoesthesia, dysesthesia, hyperkinesia[Ref]


Common (1% to 10%): Taste perversion

Uncommon (0.1% to 1%): Diarrhea, nausea, vomiting, dry mouth

Frequency not reported: Dyspepsia, abdominal pain, halitosis[Ref]


Uncommon (0.1% to 1%): Earache, otorrhagia, tinnitus, fever

Frequency not reported: Transient loss of hearing, otitis externa, otitis media, inflammation, pain, fungal infection[Ref]


Frequency not reported: Coughing, pharyngitis, rhinitis, sinusitis[Ref]


Frequency not reported: Hypertension, hot flush, tachycardia[Ref]


Frequency not reported: Insomnia

Postmarketing reports: Transient neuropsychiatric disturbances[Ref]


1. "Product Information. Floxin otic (ofloxacin otic)." Daiichi Pharmaceuticals, Fort Lee, NJ.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.