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User Reviews for Keflex

Keflex has an average rating of 7.2 out of 10 from a total of 81 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 21% reported a negative effect.

Condition Avg. Rating Reviews Compare
Skin or Soft Tissue Infection  
6.2
27 reviews 162 medications
Bacterial Infection  
8.0
20 reviews 171 medications
Bladder Infection  
8.0
20 reviews 82 medications
Acne  Off-label
7.5
4 reviews 526 medications
Kidney Infections  
9.0
4 reviews 94 medications
Upper Respiratory Tract Infection  
4.3
4 reviews 120 medications
Bone infection  
7.0
1 reviews 65 medications
Otitis Media  
8.0
1 reviews 137 medications
Summary of Keflex reviews 7.2 81 reviews

Reviews may be edited to correct grammar/spelling, or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published.

Reviews for Keflex

lh · Taken for less than 1 month April 12, 2020

For Bladder Infection: “I have suffered with urine infections on and off for years and was always given macrobid or trimethprim which never cleared it up for long or completely - and also gave me severe side effects. A new doctor started me on keflex and it has cleared it up properly - very minimal side effects if any”

10 / 10
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Hermajesteee · Taken for less than 1 month September 2, 2019

For Bladder Infection: “I started with a bladder infection on Sunday. I was urinating every 10-15 minutes and it was so painful and I felt a lot of pressure. I called the doctor and I was put on Bactrim on Monday night. The bactrim gave me the spins, constipation and anxiety. It was a nightmare!!! After 5 doses of Bactrim, my infection kept getting worse. I called the doctor and they switched me to Keflex. I started the Keflex at 9 pm and in less than 24 hours I felt much better. No side effects except a little bit of nausea and dizziness so remember to eat when you take it. It is a miracle drug for urinary infections and bladder infections.”

10 / 10
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Fatima · Taken for less than 1 month June 6, 2020

For Bladder Infection: “So I ended a Saturday at the ER, I ended up having a urinary infection a severe one. The PA prescribed Keflex 500 mg 7 Days - it really helped after 2 days but I noticed that it does bring out side effects on myself. I feel nauseous, tired, agitated, eyes feel hot, headaches even though I took 2 Advil it was still there. I also feel super anxious, I been having mood swings, I feel more sad and somehow more depressed than I’ve have been in the past. And I still have one more day to go”

8 / 10
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eisheth666 · Taken for less than 1 month March 27, 2020

For Bladder Infection: “I was prescribed Keflex twice a day for 7 days for UTI but I only lasted 4 days. Before I took this medication I had some anxiety, but no other mental health issues besides my ADHD. The 2nd day I took it I became psychotic. I was severely depressed, paranoid, convinced everyone was talking about me or working against me. I cried all day. My mind was racing & convincing me of all kinds of delusions about myself & those around me. I was having vivid disturbing nightmares. I couldn’t eat anything. Constantly felt like I was going to vomit & slept from the time I got home from work until the next morning when I got up for work. I have been on antibiotics before, but this was my first AND LAST time I will ever take this.”

1 / 10
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Anonymous · Taken for less than 1 month June 11, 2012

For Bacterial Infection: “I was prescribed Keflex (Cephalexin) after having surgery to prevent infection, and wanted to add to the list of side effects. They do not mention acid reflux, which I had every time I took the capsule (4 times a day, for 10 days). Also women need to take a probiotic while on this medication as it decreases natural flora and you can get yeast infection. I learned this the hard way by not eating enough yogurt while on this medication and not taking any probiotics. Just wanted to give a heads up and hopefully spare many women this highly uncomfortable experience.”

5 / 10
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All gone · Taken for less than 1 month February 25, 2014

For Skin or Soft Tissue Infection: “I had recurring boils in one area. They would show up randomly so the dr. was never able to take a culture since they would come to a head and then pop whenever. He put me on a 20 day regimen of Keflex (500) and another ointment antibiotic that he told me to dab into my nose. He said for some odd reason, boils seem to start in the nose. I followed the instructions and had a minor recurrence several months later. I went immediately to see him so he put me back on Keflex. These boils were clustered and leaving scars in the area. They haven't recurred and the scars are gone. Since I caught them starting the 2nd time, they never had a chance to come to a head because I stayed on top of it. I highly recommend it for a skin bacterial infection.”

9 / 10
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Anonymous May 9, 2011

For Bladder Infection: “It helped in getting rid of my bladder infection but I was out in the sun for half the day doing some work outside, and I got horribly burnt and a bad sun rash. So just try to avoid the sun while on this medication.”

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Frequently asked questions

Shedoc · Taken for 10 years or more April 26, 2017

For Bladder Infection: “I have a double whammy: I have interstitial cystitis (which feels like a constant bladder infection), and on top of that I'm prone to actual bladder infections. I've learned to be able to tell the difference between a bladder infection and a cystitis flare up. I have a lot of drug allergies and can not take sulfa drugs or Cipro, which are commonly prescribed for bladder infections. Keflex has been the only antibiotic that I can take that doesn't give me any side effects and gets rid of the infection. It's saved my bacon on numerous occasions. I also prophylactically take Acidophilus orally to avoid yeast infections. It all works like a charm. I have NEVER had a bad side effect from Keflex.”

10 / 10
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LuvNature October 15, 2019

For Bacterial Infection: “My Endodontist put me on Keflex (Cephalexin) 500 mg per day 4 X per day for a bacterial infection for a root canal that had to be retreated. I was skeptical as I often cannot finish antibiotics due to the awful side effects. I am very sensitive to medicine. This one has had no side effects for me. With that being said, I do take a probiotic (florajen) several hours before taking Keflex. The probiotic is taken 1 x per day while on antibiotics and is found in the pharmacy as it has to be refrigerated. No prescription is required for probiotic.”

10 / 10
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M&M · Taken for less than 1 month March 15, 2021

For Bladder Infection: “Had a really bad UTI and was prescribed Keflex. I have a lot of anxiety when it comes to taking medications. I take Keflex with Zofran just as a precaution and also with food before I take it. No side effects besides some gas here and there. After taking the first dose my UTI symptoms started to go away within the first five or so hours. Keflex is always my go to when I have a UTI, it works so well!! Also after taking a pill I drink about 32oz of water with it”

10 / 10
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Vegasgirl22 July 2, 2014

For Skin or Soft Tissue Infection: “Got multiple venomous spider bites on left buttocks... Turned into a staph infection. Before taking the medicine I was in so much pain I could barely sit or lay down. Been on the medicine for two days now at 500mg twice a day (along with Epsom salt baths) and it has already GREATLY improved my infection, the sores, and my ability to sit!”

8 / 10
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Zillakami February 17, 2019

For Bacterial Infection: “I was prescribed 500mg (Keflex) four times a day, for ten days. This was for a boil that I've had for eight years, I thought it was a pimple but when it got worse then ever I saw a doctor who confirmed it as a boil which then proceeded to try lancing and squeezing it I almost become unconscious this is how bad it has become. Anyways you are here for the drug review, the only side effect that I noticed was a slight tired feeling. I have anxiety so I didn't take the pills until around a week after being prescribed for a fear of side effects, there is nothing to be worried about trust that it will help you. Now my boil is completely gone and I can relax.”

9 / 10
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rindarita February 17, 2009

For Bladder Infection: “I usually never have side effects from antibiotics, but I had moderate dizziness and nausea. The nausea is not bad enough to send me to bed all day, but it does interfere with my daily schedule and leaves me extremely worn out and fatigued. It is frustrating. I have to take it four times a day for ten days.”

3 / 10
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ms. ng · Taken for 10 years or more March 21, 2015

For Bladder Infection: “Cystitis for what seems forever. Take Keflex 500mg, when an attack occurs. Told later by chemist who knew how often I get cystitis, could go on preventative 250mg daily so saw Dr. who said OK. After being months free, Dr said no, go off it for a while. Three weeks later, worst dose of Cystitis ever. Luckily have Keflex on hand so along with Ural, will be seeing Dr. very soon. What's the risk of being on a preventative dose every day?”

10 / 10
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hi5 · Taken for less than 1 month October 30, 2012

For Bacterial Infection: “I had an abscess on my upper gum resulting from terrible dentist work. I had also been prescribed amoxicillin 500mg, however after a week of taking amoxicillin the pain/swelling did not go away it got noticeably worse. However after taking my first full dose of Keflex swelling reduced and gradually faded out by the time my dosage was complete. Would highly recommend Keflex.”

10 / 10
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SB · Taken for less than 1 month November 1, 2018

For Bacterial Infection: “Took it for 7 days for a tooth infection, took the pain away on the 3rd day, no adverse reactions. Had a reaction to Bactrim so I was hesitant to take antibiotics, however I'm confident in Keflex now. Stop stressing and take it.”

10 / 10
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all fixed up! · Taken for less than 1 month March 23, 2014

For Skin or Soft Tissue Infection: “I had to take a double dosage of Keflex. I weigh about 115lbs and had to take Keflex 500mg 4 times a day for 10 days. I didn't have any issues with side effects or drinking alcohol while on it. It was prescribed as a precaution after I accidentally got a cut on my leg that required 13 stitches. The only dissatisfactory attribute was the horrid sulfur smell of the capsules.”

9 / 10
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More FAQ

Jean · Taken for less than 1 month May 28, 2019

For Bladder Infection: “Took 500mg dose of Keflex twice a day for one week - I had a UTI. Side effects were diarrhea, headaches, felt depressed, upset stomach & nausea. Now I’m having stomach cramping. Just hope the urinary tract infection I had is gone after taking this strong antibiotic.”

10 / 10
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Bookie1976 · Taken for less than 1 month March 9, 2019

For Bacterial Infection: “I went to the emergency room for a tooth abscess and they prescribed me keflex 500mg four times a day for 10 days. I have had zero side effects. It worked fast and took the infection right away. I had a little sore throat the whole 7 days but I was sneezing before I took the keflex so it probably a virus or allergies. My throat looks fine. But highly recommend Keflex cause there are barely any side effects.”

10 / 10
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AndieReviewer July 5, 2017

For Bacterial Infection: “I had a really bad cold and viral bronchitis and I ended up with nasal cellulitis of all things (infection in my nose and on my face). I took this medication and on day three, it was clearing up nicely and by day 5 the infection is gone. I had virtually no side-effects other than sleepiness, but I think that's normal when you're fighting an infection. I took 500 mg x 4 times a day and I had no stomach or intestinal issues at all. It was great.”

10 / 10
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LeeLee123 December 1, 2014

For Bladder Infection: “I have suffered with reoccurring bladder infections or symptoms of bladder infections for the past 7 years without any relief up until this past April 2014 when I was referred to a specialist by my urologist who himself could not help me. I was prescribed Keflex by this specialist and it has seemed to be the miracle I have been needing up until a month ago when my symptoms reappeared. Not sure if my body has become immune to the Keflex but I am back suffering with on again off again symptoms making my life miserable.”

9 / 10
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Myford · Taken for 10 years or more May 8, 2020

For Bacterial Infection: “Suffered from osteomyelitis in femur from age 16 ( now aged 80 ) the osteomyelitis became chronic 10 years ago and now take 2 keflex 500 a day full time. Not conscious of any side effects and infection kept under control.”

10 / 10
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Some1one · Taken for less than 1 month December 28, 2012

For Bacterial Infection: “Very effective antibiotic on two (2) separate events for oral abscess! Usually a straight Penicillin customer, I am & Doc prefers Amoxicillin (not efficacious for me). Compromise medicine: Keflex is the most foul-smelling thing I ever wanted to swallow because it works... so hold your breath!”

9 / 10
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dav185 · Taken for less than 1 month March 16, 2016

For Skin or Soft Tissue Infection: “Had an ingrown toenail infection. Was given 500mg keflex taken 4 times a day for 7 days. It is working and I have no pain in my toe. However... so far I've had diarrhea, stomach pain, tiredness and weakness, dizzy spells, yellow skin, loss of appetite, nauseous, red scratchy eyes. So most of the usual stuff. The long and short of it is my toe will be healed as long as I can deal with the side effects for a few more days.”

6 / 10
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Amangi · Taken for less than 1 month September 14, 2018

For Bladder Infection: “I have constant battles with UTI’s so I’ve taken a lot of different antibiotics. Keflex is definitely a good one but for me I have to take 500 mg three times a day so I get some side effects, mostly tired, stomach cramps and dizzy. It’s not bad though like some of the other ones I’ve taken. Before I had repeat infections I had the 500 mg twice a day dose and had very minor cramping from that dose. It’s my go to when I can take it. Drink lots of water with it too, it helps flush your system faster and get rid of the infection and it’s side effects quicker.”

9 / 10
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This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare professionals.