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Keflex and Tiredness: What Users Say

Tiredness: mentioned by 5 users (5.5%)

Based on user experiences from 91 Keflex reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

nausea 14.3%
diarrhea 9.9%
headaches 8.8%
upset stomach 7.7%
dizziness 6.6%
tiredness 5.5%
depression 4.4%
fatigue 4.4%
gas 4.4%
itching 4.4%

Reviews for Keflex

Commonly mentioned side effects
  • Zil...
  • February 17, 2019

For Bacterial Infection "I was prescribed 500mg (Keflex) four times a day, for ten days. This was for a boil that I've had for eight years. I thought it was a pimple, but when it got worse than ever, I saw a doctor who confirmed it as a boil. They then proceeded to try lancing and squeezing it. I almost became unconscious, this is how bad it had become. Anyways, you are here for the drug review. The only side effect that I noticed was a slight tired feeling. I have anxiety, so I didn't take the pills until around a week after being prescribed, for a fear of side effects. There is nothing to be worried about, trust that it will help you. Now, my boil is completely gone and I can relax."

9 / 10
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103 Report
  • Fat...
  • Taken for less than 1 month
  • June 6, 2020

For Bladder Infection "So I ended a Saturday at the ER. I ended up having a urinary infection, a severe one. The PA prescribed Keflex 500 mg for 7 days - it really helped after 2 days, but I noticed that it does bring out side effects on myself. I feel nauseous, tired, agitated, eyes feel hot, headaches. Even though I took 2 Advil, it was still there. I also feel super anxious, I've been having mood swings, I feel more sad, and somehow more depressed than I have been in the past. And I still have one more day to go."

8 / 10
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87 Report
  • Ama...
  • Taken for less than 1 month
  • September 14, 2018

For Bladder Infection "I have constant battles with UTIs, so I’ve taken a lot of different antibiotics. Keflex is definitely a good one, but for me, I have to take 500 mg three times a day, so I get some side effects, mostly tired, stomach cramps, and dizzy. It’s not bad, though, like some of the other ones I’ve taken. Before I had repeat infections, I had the 500 mg twice a day dose and had very minor cramping from that dose. It’s my go-to when I can take it. Drink lots of water with it too, it helps flush your system faster and get rid of the infection and its side effects quicker."

9 / 10
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47 Report

Frequently asked questions

  • cur...
  • Taken for 5 to 10 years
  • March 2, 2022

For Bladder Infection "I have been prescribed Keflex since they stopped using Cipro for that a few years ago. Works great every time and works within hours. Makes me a little tired and I have a bit of a headache, but I think that might have to do with my body trying to heal itself. I always ask for it if it will treat the bacteria that caused my UTI. They won't prescribe this for some bacteria... FYI. I like that this drug has been around for years and years. Makes me feel safer about taking it."

10 / 10
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15 Report
  • kli...
  • August 31, 2011

For Bone infection "Very hard to manage diarrhea while taking the antibiotic. Very tired and stomach was distended."

7 / 10
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53 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.