Skip to main content

Keflex and Diarrhea: What Users Say

Diarrhea: mentioned by 9 users (9.9%)

Based on user experiences from 91 Keflex reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

nausea 14.3%
diarrhea 9.9%
headaches 8.8%
upset stomach 7.7%
dizziness 6.6%
tiredness 5.5%
depression 4.4%
fatigue 4.4%
gas 4.4%
itching 4.4%

Reviews for Keflex

Commonly mentioned side effects
  • dav...
  • Taken for less than 1 month
  • March 16, 2016

For Skin or Soft Tissue Infection "Had an ingrown toenail infection. Was given 500mg Keflex taken 4 times a day for 7 days. It is working and I have no pain in my toe. However, so far I've had diarrhea, stomach pain, tiredness and weakness, dizzy spells, yellow skin, loss of appetite, nausea, red scratchy eyes. So most of the usual stuff. The long and short of it is my toe will be healed as long as I can deal with the side effects for a few more days."

6 / 10
Was this helpful?YesNo
90 Report
  • Jea...
  • Taken for less than 1 month
  • May 28, 2019

For Bladder Infection "Took a 500 mg dose of Keflex twice a day for one week - I had a UTI. Side effects were diarrhea, headaches, felt depressed, upset stomach, and nausea. Now I’m having stomach cramping. Just hope the urinary tract infection I had is gone after taking this strong antibiotic."

10 / 10
Was this helpful?YesNo
52 Report
  • Tes...
  • Taken for less than 1 month
  • July 8, 2019

For Acne "I started taking this medication initially for an infection from a bug bite. After three days of being on the medication, I noticed all of my skin is clear and appears to be glowing, and my pores have shrunk so much. I’m in my early 30s and still suffer from acne occasionally, mostly hormonal acne, and this is amazing. I don’t want to get off of it now. I was on doxycycline for months in my early 20s, which also had a similar effect. The only side effects from this medication initially were a headache and diarrhea, but that went away after one day, and I’m staying on probiotics to help regulate."

10 / 10
Was this helpful?YesNo
22 Report

Frequently asked questions

  • jes...
  • November 23, 2020

For Upper Respiratory Tract Infection "I went to the ER, they said I had a UTI, so they gave me Keflex 500 mg 4 times a day for a week. I despise ANY medication because of the side effects, but I didn’t want a kidney infection as that’s way worse, so I took it. I had nausea and some mild diarrhea about an hour in, normal, right? So, a few days in, I felt like I was hit by a truck. I woke up fatigued, my anxiety was so bad, and I developed an achy back that lasted a week even after I was done taking it! I still have some mild diarrhea every day, and it’s been a week since I’ve finished the medicine. I have no clue how I pulled through and took all of it. It did indeed clear up my infection, but I still feel sick. I know it’s a turn-off reading this, and it makes you not want to take the medicine, but you HAVE TO unless you want a kidney infection, which is way worse, and you’ll be put on even more antibiotics if that happens. Just pull on through, but if you genuinely don’t feel good when taking it, talk to your doctor."

5 / 10
Was this helpful?YesNo
13 Report
  • Ros...
  • Taken for less than 1 month
  • August 7, 2020

For Bladder Infection "I had cystitis and was put on Macrobid for 5 days, only to find out it didn’t do a thing for the infection. My Dr. gave me an injection of Rocephin in the office and suggested Keflex for 7 days, three times a day (500 mg). The Rocephin gave me a stomach ache and diarrhea, then I took Keflex, and it made me queasy the rest of the day. The second pill I was fine and have remained side effect-free since then. I finish my course tomorrow but still feel the cramping and mild pain from a UTI, so I’m not sure this antibiotic worked either. We’ll see!"

9 / 10
Was this helpful?YesNo
7 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
  • RZM...
  • Taken for less than 1 month
  • January 17, 2015

For Bladder Infection "Prescribed by ER doc for bladder infection. It's giving me dry mouth, diarrhea, and bad gas but it's tolerable. Drink lots of water right after you take it."

8 / 10
Was this helpful?YesNo
80 Report
  • kli...
  • August 31, 2011

For Bone infection "Very hard to manage diarrhea while taking the antibiotic. Very tired and stomach was distended."

7 / 10
Was this helpful?YesNo
53 Report

More FAQ

  • Bri...
  • Taken for less than 1 month
  • August 8, 2016

For Bacterial Infection "I was required to take 4 Keflex before a dental procedure. I got diarrhea really bad and ended up in the emergency room getting fluids from being dehydrated."

2 / 10
Was this helpful?YesNo
23 Report
  • Sta...
  • Taken for less than 1 month
  • September 24, 2021

For Skin or Soft Tissue Infection "Very bad reaction to this medication. Multiple bouts of diarrhea and stomach cramps."

1 / 10
Was this helpful?YesNo
5 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.