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Keflex and Itching: What Users Say

Itching: mentioned by 4 users (4.4%)

Based on user experiences from 91 Keflex reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

nausea 14.3%
diarrhea 9.9%
headaches 8.8%
upset stomach 7.7%
dizziness 6.6%
tiredness 5.5%
depression 4.4%
fatigue 4.4%
gas 4.4%
itching 4.4%

Reviews for Keflex

Commonly mentioned side effects
  • Din...
  • Taken for less than 1 month
  • April 19, 2020

For Kidney Infections "Had a bad kidney infection, given MacroBID for 3 days. After 2 days, it wasn't working, given another 4 days' worth. After another 2 days, it still wasn't working. Called an online private doctor, prescribed Keflex 500 mg, 3 times a day for 7 days. Kidney infection calmed down after 2 days, wasn't sure if it was doing anything for bladder infection, still had pain and discomfort throughout the 7-day course. Side effects: severe itchiness, particularly on the torso. When finished with the course, still had bladder discomfort, but worse was the itch! 2 days later, the itch on the body was gone, but hands and fingers were still really bad, constant itching, scratching the skin raw. Read that Keflex stays in the system for 72 hours. Have had muscle pain throughout the course, which I am confused about whether the kidney infection is getting better as my back muscles hurt. No stomach problems. Can say Keflex sorted the kidney infection, not sure about the bladder infection."

8 / 10
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18 Report
  • owi...
  • Taken for less than 1 month
  • January 5, 2021

For Skin or Soft Tissue Infection "I was taking Bactrim for 2 days with no improvement before being prescribed Keflex QID for 7 days to take with Bactrim for an infected cut on my wrist from punching glass. As soon as I began Keflex, I started noticing improvement. It's hard to say whether the improvement or my side effects were from Keflex or Bactrim, so take this with a grain of salt. I had tachycardia, chills, nausea, indigestion, gas pain that felt like chest pain, itching on arms/legs, petechiae on my upper arms, frequent urination, and eventual yeast infection for which I had to take Diflucan. I had some symptoms together, and some separate. Most of my side effects came at night, though, so it could've been some kind of reaction between the two? The side effects definitely hit me harder in the beginning, but by my 5th day of Keflex, almost all side effects had subsided. I suggest taking with probiotics that can survive stomach acid and easily digestible food and drinking a lot of water."

6 / 10
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5 Report
  • UNC...
  • Taken for less than 1 month
  • August 21, 2022

For Skin or Soft Tissue Infection "20 yo son took Keflex generic at 7 am Friday for a gross shin wound. After 3 doses, by Saturday afternoon, he had a fever of 102.6. The hospital deemed him COVID positive via a rapid test, though son only had a fever as symptoms of anything. The staff seemed excited to tell each of me, hubby, and my parents without son’s permission. Hubby and I each tested negative on non-rapid tests this morning. We will continue Keflex until the dosage is complete, but I would not take this med or allow my son to take it again. My mother is allergic to Keflex. It makes her itch and choke. I’m very certain the Keflex is causing my son’s fever, but COVID is a payday, so we just have to deal with it. He is allergic to amoxicillin."

4 / 10
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7 Report

Frequently asked questions

  • Bra...
  • June 20, 2011

For Skin or Soft Tissue Infection "Quickly cleared up cellulitis that was painful and itchy on the crease of my leg. 7 days, twice daily, 500 mg."

10 / 10
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58 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.