Ciprofloxacin / Fluocinolone Otic Dosage

Medically reviewed by Drugs.com. Last updated on Aug 13, 2024.

Applies to the following strengths: 0.3%-0.025%

Usual Adult Dose for Otitis Media

Ciprofloxacin 0.75 mg-fluocinolone 0.0625 mg (1 single-dose vial) instilled into the affected ear canal 2 times a day (every 12 hours)

Duration of therapy: 7 days

Comments:

The vial should be warmed in the hands for 1 to 2 minutes prior to administration to avoid dizziness associated with instillation of a cold solution into the ear canal.
Once instilled, the tragus should be pumped inward 4 times, then the patient should remain in the position for at least 1 minute.

Use: Treatment of acute otitis media with tympanostomy tubes (AOMT) due to Haemophilus influenzae, Moraxella catarrhalis, Pseudomonas aeruginosa, Staphylococcus aureus, and/or Streptococcus pneumoniae

Usual Pediatric Dose for Otitis Media

6 months and older: Ciprofloxacin 0.75 mg-fluocinolone 0.0625 mg (1 single-dose vial) instilled into the affected ear canal 2 times a day (every 12 hours)

Duration of therapy: 7 days

Comments:

The vial should be warmed in the hands for 1 to 2 minutes prior to administration to avoid dizziness associated with instillation of a cold solution into the ear canal.
Once instilled, the tragus should be pumped inward 4 times, then the patient should remain in the position for at least 1 minute.

Use: Treatment of AOMT due to H influenzae, M catarrhalis, P aeruginosa, S aureus, and/or S pneumoniae

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS:

Hypersensitivity to either active component, other corticosteroids, other quinolones, or any of the ingredients
Viral infections of the ear canal, including fungal otic, herpes simplex, and varicella infections

Safety and efficacy have not been established in patients younger than 6 months.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

Patients should lie with the affected ear upward before administration.
If both ears are affected, the administration procedure should be repeated for the opposite ear.
Use of additional otic agents should be given

Storage requirements:

This drug should be protected from light by being kept inside the foil pouch until ready to use.
Unused vials should be discarded 7 days after opening the pouch.

General:

Each vial delivers 0.25 mL, which is equivalent to 0.75 mg of ciprofloxacin and 0.0625 mg fluocinolone. Vials are intended for single-use only and should be discarded after use.
Limitations of use: This drug is indicated for otic use only. It is not indicated for injection, inhalation, ophthalmic, or oral use.

Patient advice:

Patients should be told that this drug is for otic use only.
Patients should be instructed to wash their hands before and after applying this drug.
Caution patients to warm the vial in the hands for 1 to 2 minutes to prevent dizziness during administration.
Patients should be encouraged to avoid missing doses and complete the entire course of therapy.
Patients should be advised to immediately report any signs/symptoms of hypersensitivity reactions.