Ciprofloxacin / Fluocinolone Otic Side Effects
Medically reviewed by Drugs.com. Last updated on Dec 27, 2023.
Applies to ciprofloxacin/fluocinolone otic: otic solution.
Important warnings
This medicine can cause some serious health issues
Follow all directions on your medicine label and package.
Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
Get emergency medical help if you have signs of an allergic reaction: hives, rash, itching; dizziness; fast or pounding heartbeat; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
-
the first sign of any skin rash, no matter how mild;
-
new or worsening symptoms of infection; or
-
ear drainage that continues for up to 6 months after you have finished all doses of this medicine.
Common side effects may include:
-
ear pain, swelling, or itching;
-
problems with balance; or
-
scar tissue on part of the ear.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
For healthcare professionals
Applies to ciprofloxacin/fluocinolone otic: otic solution.
General adverse events
The most commonly reported side effects are otorrhea and the development of excessive granulation tissue.[Ref]
Other
- Common (1% to 10%): Ear discomfort, ear pain, ear pruritus, otorrhea
- Uncommon (0.1% to 1%): Auricular swelling, contralateral otitis media, crying, device occlusion (tympanostomy tube obstruction), ear congestion, ear infection/fungal ear infection, fatigue, hypoacusis, tinnitus, tympanic membrane disorder
Ciprofloxacin:
- Common (1% to 10%): Otorrhea, ear infection
- Uncommon (0.1% to 1%): Ear pruritus, auricular swelling
Fluocinolone:
- Common (1% to 10%): Otorrhea
- Uncommon (0.1% to 1%): Ear infection[Ref]
Nervous system
- Common (1% to 10%): Dysgeusia
- Uncommon (0.1% to 1%): Balance disorder, paresthesia/tingling in ears, dizziness, headache
Ciprofloxacin:
- Frequency not reported: Loss of consciousness[Ref]
Dermatologic
- Common (1% to 10%): Excessive granulation tissue
- Uncommon (0.1% to 1%): Exanthematous rash, rash, skin exfoliation
Ciprofloxacin:
Fluocinolone:
- Uncommon (0.1% to 1%): Excessive granulation tissue[Ref]
Cardiovascular
- Uncommon (0.1% to 1%): Flushing
Ciprofloxacin:
- Frequency not reported: Cardiovascular collapse[Ref]
Local
- Uncommon (0.1% to 1%): Medication residue[Ref]
Gastrointestinal
Psychiatric
- Uncommon (0.1% to 1%): Irritability[Ref]
Immunologic
- Uncommon (0.1% to 1%): Candidiasis[Ref]
Musculoskeletal
Ciprofloxacin:
- Frequency not reported: Achilles, hand, other tendon, or shoulder rupture[Ref]
Patients given systemic fluoroquinolones have reported tendon rupture requiring surgery and/or resulting in prolonged disability. Risk of tendon rupture may be higher in those receiving corticosteroids concomitantly, especially in older patients and in high-stress tendons. It is unknown whether otic formulations are associated with an increased risk of tendon rupture.[Ref]
Hypersensitivity
- Postmarketing reports: Allergic reaction
Ciprofloxacin:
- Frequency not reported: Angioedema, fatal anaphylactic/hypersensitivity reactions[Ref]
Ocular
- Frequency not reported: Blurred vision[Ref]
Respiratory
Ciprofloxacin:
See also:
Augmentin
Augmentin is a prescription antibiotic combining amoxicillin and clavulanate to treat bacterial ...
Bactrim
Bactrim (sulfamethoxazole and trimethoprim) is an antibiotic used to treat ear infections, urinary ...
Botox
Botox is used for cosmetic purposes and to treat overactive bladder symptoms, urinary incontinence ...
Keflex
Keflex (cephalexin) is used to treat infections caused by bacteria, including respiratory ...
Erythromycin
Erythromycin is a macrolide antibiotic used to treat bacterial infections. Includes erythromycin ...
Sulfamethoxazole/trimethoprim
Sulfamethoxazole/trimethoprim systemic is used for acne, bacterial infection, bacterial skin ...
Amoxicillin/clavulanate
Amoxicillin and clavulanate potassium is a combination antibiotic used to treat bacterial ...
Cefdinir
Cefdinir systemic is used for bacterial infection, bronchitis, middle ear infections, pneumonia ...
Ceftriaxone
Ceftriaxone systemic is used for bacteremia, bacterial endocarditis prevention, bacterial ...
Cephalexin
Cephalexin is a cephalosporin antibiotic used to treat bacterial infections like respiratory, skin ...
References
1. Cerner Multum, Inc. "UK Summary of Product Characteristics."
2. (2016) "Product Information. Otovel (ciprofloxacin-fluocinolone otic)." Arbor Pharmaceuticals
More about ciprofloxacin / fluocinolone otic
- Compare alternatives
- Pricing & coupons
- Reviews (1)
- Dosage information
- During pregnancy
- Drug class: otic steroids with anti-infectives
- En español
Patient resources
Other brands
Professional resources
Other brands
Related treatment guides
Further information
Ciprofloxacin/fluocinolone otic side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.