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Ciprofloxacin / fluocinolone otic Side Effects

For the Consumer

Applies to ciprofloxacin / fluocinolone otic: otic solution

Get emergency medical help if you have signs of an allergic reaction: hives, rash, itching; dizziness; fast or pounding heartbeat; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • the first sign of any skin rash, no matter how mild;

  • new or worsening symptoms of infection; or

  • ear drainage that continues for up to 6 months after you have finished all doses of this medicine.

Common side effects may include:

  • ear pain, swelling, or itching;

  • problems with balance; or

  • scar tissue on part of the ear.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to ciprofloxacin / fluocinolone otic: otic solution


The most commonly reported side effects are otorrhea and the development of excessive granulation tissue.[Ref]


Common (1% to 10%): Otorrhea
Uncommon (0.1% to 1%): Ear infection, ear pruritus, tympanic membrane disorder, auricular swelling
Postmarketing reports: Candidiasis, ear discomfort, hypoacusis, ear congestion, device occlusion (tympanostomy tube obstruction), tinnitus

Common (1% to 10%): Otorrhea, ear infection
Uncommon (0.1% to 1%): Ear pruritus, auricular swelling

Common (1% to 10%): Otorrhea
Uncommon (0.1% to 1%): Ear infection[Ref]


Common (1% to 10%): Excessive granulation tissue
Postmarketing reports: Skin exfoliation, flushing

Uncommon (0.1% to 1%): Excessive granulation tissue[Ref]

Nervous system

Uncommon (0.1% to 1%): Balance disorder
Postmarketing reports: Dysgeusia, paresthesia/tingling in ears, dizziness, headache[Ref]


Postmarketing reports: Allergic reaction[Ref]


1. "Product Information. Otovel (ciprofloxacin-fluocinolone otic)." Arbor Pharmaceuticals, Atlanta, GA.

Not all side effects for ciprofloxacin / fluocinolone otic may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.