Colistin Sulfate / Hydrocortisone / Neomycin / Thonzonium Bromide Otic Side Effects
Medically reviewed by Drugs.com. Last updated on Feb 28, 2025.
Applies to colistin sulfate / hydrocortisone / neomycin / thonzonium bromide otic: otic suspension.
It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly and to check for unwanted effects.
If your symptoms do not improve within 1 week or if they become worse, check with your doctor right away.
This medicine may cause permanent hearing loss (with long-term use). Do not use it for more than 10 days.
This medicine may cause serious allergic reactions. Check with your doctor right away if you have difficulty in breathing or swallowing, fast heartbeat, skin itching, rash, or redness, swelling of the face, throat, or tongue, or trouble breathing.
Serious side effects
Along with its needed effects, colistin sulfate / hydrocortisone / neomycin / thonzonium bromide otic may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking colistin sulfate / hydrocortisone / neomycin / thonzonium bromide otic:
Incidence not known
- blistering, burning, itching, peeling, rash, redness, swelling, or other signs of skin irritation
- bloody urine
- burning and itching of the skin with pinhead-sized red blisters
- change in the frequency of urination or amount of urine
- crusting, dryness, flaking, or scaling of the skin
- difficulty in breathing
- dizziness
- drowsiness
- feeling of fullness in the ears
- increased thirst
- loss of appetite
- loss of balance
- loss of hearing
- nausea
- ringing or buzzing in the ears
- swelling of the feet or lower legs
- thinning of the skin with easy bruising
- trouble in hearing
- vomiting
- weakness
Other side effects
Some side effects of colistin sulfate / hydrocortisone / neomycin / thonzonium bromide otic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Incidence not known
- acne, pimples
- burning, itching, and pain in hairy areas
- increased hair growth on the forehead, back, arms, and legs
- lightening of normal skin color
- lightening of the treated areas of dark skin
- pus at the root of the hair
- reddish purple lines on the arms, face, legs, trunk, or groin
- redness and scaling around the mouth
- softening of the skin
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More about colistin sulfate / hydrocortisone / neomycin / thonzonium bromide otic
Patient resources
- Colistin, hydrocortisone, neomycin, and thonzonium otic drug information
- Colistin, neomycin, thonzonium, and hydrocortisone (Advanced Reading)
- Neomycin, Colistin, Hydrocortisone, and Thonzonium
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Further information
Colistin sulfate/hydrocortisone/neomycin/thonzonium bromide otic side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.