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Ciprofloxacin / Dexamethasone Otic Dosage

Applies to the following strength(s): 0.3%-0.1%

The information at is not a substitute for medical advice. Always consult your doctor or pharmacist.

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Otitis Externa

4 drops in the affected ear{s} twice daily for 7 days

Usual Pediatric Dose for Otitis Media

>=6 months: 4 drops in the affected ear{s} twice daily for 7 days

Usual Pediatric Dose for Otitis Externa

>=6 months: 4 drops in the affected ear{s} twice daily for 7 days

Renal Dose Adjustments

No adjustment recommended

Liver Dose Adjustments

No adjustment recommended


Ciprofloxacin-dexamethasone otic is contraindicated in patients with viral infections, including herpes simplex, of the external ear canal.

This drug is not approved for ophthalmic use.

Superinfection with nonsusceptible organisms (i.e., yeasts, fungi) may occur with antimicrobial therapy. Cultures should be obtained and used to guide therapy if there is no improvement after 1 week of treatment. Further evaluation to exclude other causes is necessary if otorrhea is still present after a course of therapy or occurs two or more times within 6 months.

The drug should be discontinued immediately at the first appearance of a skin rash or other signs of hypersensitivity.

Systemically administered fluoroquinolones (at doses larges than those given or absorbed otically) have been associated with an increased incidence of osteochondrosis and arthropathy in juvenile animals.


No adjustment recommended

Other Comments

Before administration, the suspension should be warmed by rolling the container in the hand for 1 to 2 minutes, then shaken well. The patient should lie down with the affected ear upward while the drops are instilled and remain in this position for 60 seconds to allow the suspension to penetrate the ear. The outer ear lobe should be gently pulled upward and backward to allow the drops to flow into the ear canal.

This procedure should be repeated for the other ear, if necessary.

Patients should be advised to avoid getting the infected ear(s) wet while bathing and to avoid swimming (unless otherwise instructed by their physician).

To avoid contamination, the tip of the container should not be allowed to touch the ear, fingers, or other surfaces.

The container should be protected from light.

The unused portion should be discarded after completion of therapy.